amipace 200 tablet - Amiodarone (200mg) medicine

amipace 200 tablet

4.6 (16 reviews)
๐Ÿญ Lupin Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is amipace 200 tablet used for?

Amiodar 200 Tablet (Amiodarone) is used to treat CARDIAC. It contains Amiodarone (200mg), which Class III antiarrhythmic; blocks potassium channels, prolongs repolarization; al. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Amiodarone
  • Manufacturer: Lupin Ltd
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š amipace 200 tablet Uses & Benefits

Ventricular arrhythmias, atrial fibrillation, atrial flutter, supraventricular tachycardias

Off-label uses: Hypertrophic cardiomyopathy, prevention of atrial fibrillation post-cardiac surgery

๐Ÿ“‹ Drug Information

Generic Name(s)Amiodarone
Brand NameAmiodar 200 Tablet
ManufacturerLupin Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassClass III Agents- anti arrhythmic
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSlow and variable oral absorption; bioavailability 20-80%
DistributionExtensive distribution; accumulates in adipose tissue, liver, lungs, and skin
Protein Binding96%
MetabolismHepatic metabolism via CYP3A4 and CYP2C8; active metabolite desethylamiodarone
Half-Life26-107 days (mean 58 days)
ExcretionPrimarily biliary and fecal; minimal renal excretion
Bioavailability20-80%
Onset of Action2 days to 3 weeks (oral)
Peak Plasma Time3-7 hours
Duration of ActionWeeks to months

How It Works

Class III antiarrhythmic; blocks potassium channels, prolongs repolarization; also has class I, II, and IV effects

Mechanism Steps

1Blocks potassium channels (IKr) prolonging repolarization
2Blocks sodium channels (class I effect)
3Blocks calcium channels (class IV effect)

๐Ÿ’ก How to Take amipace 200 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of amipace 200 tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Constipation
  • Fatigue
  • Tremor
  • Photosensitivity
  • Corneal microdeposits

๐Ÿšจ Serious Side Effects

  • Pulmonary fibrosis
  • Hepatotoxicity
  • Thyroid dysfunction (hyper/hypo)
  • Proarrhythmia
  • Optic neuropathy
  • Peripheral neuropathy

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Pancreatitis
  • Interstitial pneumonitis
  • Cirrhosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Digoxin Major Increased digoxin toxicity
Flecainide Major Increased risk of arrhythmias
Simvastatin Major Increased risk of myopathy/rhabdomyolysis
Phenytoin Major Increased phenytoin levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Digoxin
  • Flecainide
  • Procainamide
  • Quinidine
  • Phenytoin
  • Cyclosporine
  • Statins (simvastatin, lovastatin)
  • Macrolide antibiotics
  • Fluoroquinolones

โšก Moderate Interactions

  • Beta-blockers
  • Calcium channel blockers
  • Anticoagulants (other)
  • Antiplatelet agents
  • Fentanyl
  • Methotrexate
  • Theophylline

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Cholestyramine
  • Grapefruit juice

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase absorption; high-fat meals may increase bioavailability

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Sinus node dysfunction, AV block (unless paced), bradycardia, iodine hypersensitivity, thyroid disease, pulmonary fibrosis, pregnancy

๐Ÿ“Š Monitoring Parameters

ECG (QT interval), liver function tests, thyroid function tests, pulmonary function tests, serum electrolytes, ophthalmic exams

๐Ÿคฑ Lactation Safety

Contraindicated; excreted in breast milk

๐Ÿ’Š Overdose Management

Supportive care; monitor ECG, liver function, thyroid; consider activated charcoal; no specific antidote

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for amipace 200 tablet

View All

Alternative brands with exact same active ingredient (Amiodarone (200mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

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