art-x tablet

4.6 (17 reviews)

Amiodarone (200mg)

🏭 Gruentzig Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is art-x tablet used for?

Amiodar 200 Tablet (Amiodarone) is used to treat CARDIAC. It contains Amiodarone (200mg), which Class III antiarrhythmic; blocks potassium channels, prolongs repolarization; al. Always consult your doctor before use. Take as prescribed.

Generic Name: Amiodarone
Manufacturer: Gruentzig Pharmaceuticals
Form: Allopathy
Pregnancy Category: D
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 art-x tablet Uses & Benefits

Ventricular arrhythmias, atrial fibrillation, atrial flutter, supraventricular tachycardias

Off-label uses: Hypertrophic cardiomyopathy, prevention of atrial fibrillation post-cardiac surgery

📋 Drug Information

Generic Name(s)	Amiodarone
Brand Name	Amiodar 200 Tablet
Manufacturer	Gruentzig Pharmaceuticals
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	Class III Agents- anti arrhythmic
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSlow and variable oral absorption; bioavailability 20-80%

DistributionExtensive distribution; accumulates in adipose tissue, liver, lungs, and skin

Protein Binding96%

MetabolismHepatic metabolism via CYP3A4 and CYP2C8; active metabolite desethylamiodarone

Half-Life26-107 days (mean 58 days)

ExcretionPrimarily biliary and fecal; minimal renal excretion

Bioavailability20-80%

Onset of Action2 days to 3 weeks (oral)

Peak Plasma Time3-7 hours

Duration of ActionWeeks to months

How It Works

Class III antiarrhythmic; blocks potassium channels, prolongs repolarization; also has class I, II, and IV effects

Mechanism Steps

1Blocks potassium channels (IKr) prolonging repolarization

2Blocks sodium channels (class I effect)

3Blocks calcium channels (class IV effect)

💡 How to Take art-x tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of art-x tablet

✅ Common Side Effects

Nausea
Vomiting
Constipation
Fatigue
Tremor
Photosensitivity
Corneal microdeposits

🚨 Serious Side Effects

Pulmonary fibrosis
Hepatotoxicity
Thyroid dysfunction (hyper/hypo)
Proarrhythmia
Optic neuropathy
Peripheral neuropathy

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Toxic epidermal necrolysis
Pancreatitis
Interstitial pneumonitis
Cirrhosis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Digoxin	Major	Increased digoxin toxicity
Flecainide	Major	Increased risk of arrhythmias
Simvastatin	Major	Increased risk of myopathy/rhabdomyolysis
Phenytoin	Major	Increased phenytoin levels

🚨 Major Interactions

Warfarin
Digoxin
Flecainide
Procainamide
Quinidine
Phenytoin
Cyclosporine
Statins (simvastatin, lovastatin)
Macrolide antibiotics
Fluoroquinolones

⚡ Moderate Interactions

Beta-blockers
Calcium channel blockers
Anticoagulants (other)
Antiplatelet agents
Fentanyl
Methotrexate
Theophylline

ℹ️ Minor Interactions

Cimetidine
Cholestyramine
Grapefruit juice

🍽️ Food Interactions

Grapefruit juice may increase absorption; high-fat meals may increase bioavailability

🍷 Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk

🛡️ Safety & Warnings

🚫 Contraindications

Sinus node dysfunction, AV block (unless paced), bradycardia, iodine hypersensitivity, thyroid disease, pulmonary fibrosis, pregnancy

📊 Monitoring Parameters

ECG (QT interval), liver function tests, thyroid function tests, pulmonary function tests, serum electrolytes, ophthalmic exams

🤱 Lactation Safety

Contraindicated; excreted in breast milk

💊 Overdose Management

Supportive care; monitor ECG, liver function, thyroid; consider activated charcoal; no specific antidote

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for art-x tablet

View All

Alternative brands with exact same active ingredient (Amiodarone (200mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.