amic t 500mg/250mg tablet - Tranexamic Acid (500mg) + Mefenamic Acid (250mg) medicine

Amic T 500mg/250mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Stenhill Labs ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is amic t 500mg/250mg tablet used for?

Amic T 500mg/250mg Tablet is a combination of Tranexamic Acid and Mefenamic Acid used to treat heavy menstrual bleeding (menorrhagia). Tranexamic Acid helps blood clots to form and reduces bleeding, while Mefenamic Acid relieves pain and inflammation. It is taken twice daily as prescribed.

  • Generic Name: Tranexamic Acid + Mefenamic Acid
  • Manufacturer: Stenhill Labs
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š amic t 500mg/250mg tablet Uses & Benefits

Menorrhagia, dysmenorrhea, heavy menstrual bleeding

Off-label uses: Epistaxis, dental bleeding, trauma-related bleeding

๐Ÿ“‹ Drug Information

Generic Name(s)Tranexamic Acid + Mefenamic Acid
Brand NameAbdotic Plus Tablet
ManufacturerStenhill Labs
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassAntifibrinolytic + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely; crosses placenta
Protein BindingTranexamic acid: ~3%; Mefenamic acid: >90%
MetabolismTranexamic acid: minimal hepatic; Mefenamic acid: hepatic via CYP2C9
Half-LifeTranexamic acid: 2-11 hours; Mefenamic acid: 2-4 hours
ExcretionTranexamic acid: renal (90% unchanged); Mefenamic acid: renal and biliary
BioavailabilityTranexamic acid: ~34%; Mefenamic acid: ~90%
Onset of ActionTranexamic acid: 2-3 hours; Mefenamic acid: 1-2 hours
Peak Plasma TimeTranexamic acid: 3 hours; Mefenamic acid: 2-4 hours
Duration of ActionTranexamic acid: 6-8 hours; Mefenamic acid: 4-6 hours

How It Works

Tranexamic acid: inhibits plasminogen activation; Mefenamic acid: inhibits COX-1/COX-2

Mechanism Steps

1Tranexamic acid reversibly binds to plasminogen, blocking its conversion to plasmin
2Inhibition of fibrinolysis stabilizes blood clots
3Mefenamic acid inhibits cyclooxygenase (COX-1 and COX-2) enzymes

๐Ÿ’ก How to Take amic t 500mg/250mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of amic t 500mg/250mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache

๐Ÿšจ Serious Side Effects

  • Thrombosis
  • Anaphylaxis
  • GI bleeding
  • Renal failure

โš ๏ธ Rare Side Effects

  • Color vision disturbance
  • Hypotension
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal bleeding
ACE Inhibitors Moderate Reduced antihypertensive effect

๐Ÿšจ Major Interactions

  • Warfarin
  • Aspirin
  • Clopidogrel
  • Heparin
  • NSAIDs

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Lithium
  • Methotrexate

โ„น๏ธ Minor Interactions

  • Antacids
  • Corticosteroids

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Active peptic ulcer, severe renal impairment, history of hypersensitivity, thromboembolic disease

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, CBC, signs of bleeding

๐Ÿคฑ Lactation Safety

Use with caution; excreted in milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal

โฐ Missed Dose

Take as soon as remembered; skip if near next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

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