ambrohist s syrup - Terbutaline (NA) + Ambroxol (NA) medicine

Ambrohist S Syrup - Uses, Price, Side Effects

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๐Ÿญ Biochem Pharmaceutical Industries ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is ambrohist s syrup used for?

Ambrohist S Syrup is a combination of Terbutaline (a bronchodilator) and Ambroxol (a mucolytic) used to relieve cough and chest congestion in respiratory conditions like asthma and bronchitis. It works by relaxing airway muscles and thinning mucus for easier breathing.

  • Generic Name: Terbutaline + Ambroxol
  • Manufacturer: Biochem Pharmaceutical Industries
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š ambrohist s syrup Uses & Benefits

Bronchial asthma, chronic bronchitis, COPD with excessive mucus.

Off-label uses: None commonly reported.

๐Ÿ“‹ Drug Information

Generic Name(s)Terbutaline + Ambroxol
Brand NameAstharid Plus Tablet
ManufacturerBiochem Pharmaceutical Industries
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassBronchodilator + Mucolytic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTerbutaline: Well absorbed orally; Ambroxol: Rapidly absorbed from GI tract.
DistributionTerbutaline: Crosses placenta; Ambroxol: Widely distributed, crosses blood-brain barrier.
Protein BindingTerbutaline: ~20%; Ambroxol: ~90%.
MetabolismTerbutaline: Hepatic via conjugation; Ambroxol: Hepatic via glucuronidation.
Half-LifeTerbutaline: 3-4 hours; Ambroxol: 7-12 hours.
ExcretionTerbutaline: Renal (60% unchanged); Ambroxol: Renal (90% metabolites).
BioavailabilityTerbutaline: ~15-20% (oral); Ambroxol: ~70-80%.
Onset of ActionTerbutaline: 30 min; Ambroxol: 1 hour.
Peak Plasma TimeTerbutaline: 2-4 hours; Ambroxol: 1-3 hours.
Duration of ActionTerbutaline: 4-6 hours; Ambroxol: 6-8 hours.

How It Works

Terbutaline: Beta-2 adrenergic agonist; Ambroxol: Increases mucus clearance and surfactant production.

Mechanism Steps

1Terbutaline binds to beta-2 adrenergic receptors on bronchial smooth muscle.
2Activation of adenylate cyclase increases cAMP levels.
3cAMP causes relaxation of bronchial smooth muscle (bronchodilation).

๐Ÿ’ก How to Take ambrohist s syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of ambrohist s syrup

โœ… Common Side Effects

  • Tremor
  • Headache
  • Nausea
  • Palpitations
  • Cough

๐Ÿšจ Serious Side Effects

  • Hypokalemia
  • Arrhythmias
  • Paradoxical bronchospasm
  • Severe allergic reactions

โš ๏ธ Rare Side Effects

  • Seizures
  • Pulmonary edema
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Beta-blockers Moderate May reduce bronchodilator effect
MAOIs Major Increased risk of hypertensive crisis
Diuretics Moderate Hypokalemia risk

๐Ÿšจ Major Interactions

  • Beta-blockers
  • MAOIs
  • Tricyclic antidepressants

โšก Moderate Interactions

  • Diuretics
  • Corticosteroids
  • Xanthines

โ„น๏ธ Minor Interactions

  • Anticholinergics
  • Sympathomimetics

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS side effects.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Moderate
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, tachyarrhythmias, hypertrophic obstructive cardiomyopathy, severe hypertension.

๐Ÿ“Š Monitoring Parameters

Heart rate, blood pressure, serum potassium, pulmonary function tests.

๐Ÿคฑ Lactation Safety

Caution; Terbutaline excreted in milk, Ambroxol unknown.

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, symptomatic treatment; beta-blockers for severe tachycardia.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

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