amatic syrup - Ambroxol (15mg) + Guaifenesin (50mg) medicine

Amatic Syrup - Uses, Price, Side Effects

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๐Ÿญ Ultra Chiron Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is amatic syrup used for?

Amatic Syrup is a combination of Ambroxol (15mg) and Guaifenesin (50mg) used to treat cough with phlegm. Ambroxol thins mucus, while Guaifenesin helps expel it, providing relief from chest congestion. It is suitable for adults and children under medical guidance.

  • Generic Name: Ambroxol + Guaifenesin
  • Manufacturer: Ultra Chiron Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š amatic syrup Uses & Benefits

Productive cough, acute/chronic bronchitis, COPD, bronchiectasis

Off-label uses: None well-established

๐Ÿ“‹ Drug Information

Generic Name(s)Ambroxol + Guaifenesin
Brand NameAmbrolite-S Expectorant
ManufacturerUltra Chiron Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic and Expectorant
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in body tissues
Protein BindingAmbroxol: ~90%; Guaifenesin: ~50%
MetabolismAmbroxol: Hepatic; Guaifenesin: Hepatic
Half-LifeAmbroxol: 7-12 hours; Guaifenesin: 1 hour
ExcretionAmbroxol: Renal; Guaifenesin: Renal
BioavailabilityAmbroxol: ~70%; Guaifenesin: ~95%
Onset of Action30-60 minutes
Peak Plasma TimeAmbroxol: 1-3 hours; Guaifenesin: 0.5-1 hour
Duration of Action6-12 hours

How It Works

Ambroxol increases secretion of respiratory tract fluid and reduces mucus viscosity; Guaifenesin increases respiratory tract fluid to thin bronchial secretions.

Mechanism Steps

1Ambroxol stimulates serous cells in bronchial glands to increase thin secretions
2Ambroxol depolymerizes mucopolysaccharides, reducing mucus viscosity
3Guaifenesin increases respiratory tract fluid volume, thinning mucus

๐Ÿ’ก How to Take amatic syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of amatic syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction
  • Stevens-Johnson syndrome
  • Bronchospasm

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Angioedema
  • Renal calculi

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Cough Suppressants Moderate Reduced effectiveness of expectorant
MAOIs Moderate Increased risk of serotonin syndrome

๐Ÿšจ Major Interactions

  • Cough suppressants (e.g., codeine)
  • Anticholinergics

โšก Moderate Interactions

  • MAOIs
  • Antihypertensives

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase sedation

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to any component, peptic ulcer, severe hepatic/renal impairment

๐Ÿ“Š Monitoring Parameters

Cough frequency, sputum characteristics, respiratory function

๐Ÿคฑ Lactation Safety

Use with caution; not recommended

๐Ÿ’Š Overdose Management

Gastric lavage, supportive care, monitor for CNS depression

โฐ Missed Dose

Take as soon as remembered; skip if near next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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