alvotin f 10mg/160mg tablet - Atorvastatin (10mg) + Fenofibrate (160mg) medicine

alvotin f 10mg/160mg tablet - Uses, Price, Side Effects & Substitutes

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🏭 Alvio Pharma πŸ“¦ Varies by brand πŸ’Š Allopathy πŸ“… Updated: Jun 28, 2026
⚠️ Hepatotoxicity Risk πŸ“‹ Prescription Required πŸ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is alvotin f 10mg/160mg tablet used for?

Atorlip-F Tablet (Atorvastatin + Fenofibrate) is used to treat CARDIAC. It contains Atorvastatin (10mg) + Fenofibrate (160mg), which Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Fenofib. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Atorvastatin + Fenofibrate
  • Manufacturer: Alvio Pharma
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
πŸ’‘ Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

πŸ’Š alvotin f 10mg/160mg tablet Uses & Benefits

Primary hypercholesterolemia, mixed dyslipidemia, hypertriglyceridemia.

Off-label uses: Secondary prevention of cardiovascular events, non-alcoholic fatty liver disease.

πŸ“‹ Drug Information

Generic Name(s)Atorvastatin + Fenofibrate
Brand NameAtorlip-F Tablet
ManufacturerAlvio Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassLipid-lowering agents (Statin + Fibrate)
Route of AdministrationOral
StorageStore at 20-25Β°C, protect from light and moisture.
Shelf LifeAs per manufacturer

πŸ”¬ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAtorvastatin: Rapidly absorbed after oral administration; Fenofibrate: Well absorbed, absorption enhanced with food.
DistributionAtorvastatin: Extensively distributed to tissues; Fenofibrate: Highly bound to albumin.
Protein BindingAtorvastatin: β‰₯98%; Fenofibrate: ~99%
MetabolismAtorvastatin: Hepatic via CYP3A4; Fenofibrate: Hydrolysis to fenofibric acid, then glucuronidation.
Half-LifeAtorvastatin: ~14 hours; Fenofibrate: ~20 hours (fenofibric acid)
ExcretionAtorvastatin: Biliary (feces); Fenofibrate: Renal (urine) as metabolites.
BioavailabilityAtorvastatin: ~14%; Fenofibrate: ~30% (increased with food)
Onset of ActionAtorvastatin: 1-2 weeks for lipid changes; Fenofibrate: Several days to weeks.
Peak Plasma TimeAtorvastatin: 1-2 hours; Fenofibrate: 6-8 hours (fenofibric acid)
Duration of ActionAtorvastatin: Up to 24 hours; Fenofibrate: Up to 24 hours.

How It Works

Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Fenofibrate activates PPARΞ±, increasing lipolysis and VLDL clearance.

Mechanism Steps

1Atorvastatin competitively inhibits HMG-CoA reductase, reducing mevalonate and cholesterol synthesis.
2Fenofibrate activates PPARΞ±, increasing lipoprotein lipase activity and fatty acid oxidation.
3Combined effect: Decreased hepatic VLDL secretion, increased clearance of triglycerides, and upregulation of LDL receptors.

πŸ’‘ How to Take alvotin f 10mg/160mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of alvotin f 10mg/160mg tablet

βœ… Common Side Effects

  • Myalgia
  • Diarrhea
  • Nasopharyngitis
  • Headache
  • Abdominal pain

🚨 Serious Side Effects

  • Rhabdomyolysis
  • Hepatotoxicity
  • Pancreatitis
  • Renal failure
  • Angioedema

⚠️ Rare Side Effects

  • Peripheral neuropathy
  • Interstitial lung disease
  • Tendon rupture
  • Gynecomastia

Consult your doctor if you experience any unusual symptoms.

πŸ”¬ Drug Interactions

⚠️ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk
Cyclosporine Major Increased risk of myopathy/rhabdomyolysis
Gemfibrozil Major Increased risk of myopathy
Macrolide antibiotics Major Increased atorvastatin levels
Azole antifungals Major Increased atorvastatin levels
HIV protease inhibitors Major Increased atorvastatin levels
Digoxin Moderate Increased digoxin levels
Oral contraceptives Moderate Increased contraceptive levels
Colchicine Moderate Increased risk of myopathy
Niacin Moderate Increased risk of myopathy
Antacids Minor Reduced atorvastatin absorption
Rifampin Minor Reduced atorvastatin levels
St. John's Wort Minor Reduced atorvastatin levels

🚨 Major Interactions

  • Warfarin
  • Cyclosporine
  • Gemfibrozil
  • Macrolide antibiotics
  • Azole antifungals
  • HIV protease inhibitors

⚑ Moderate Interactions

  • Digoxin
  • Oral contraceptives
  • Colchicine
  • Fibrates (other)
  • Niacin

ℹ️ Minor Interactions

  • Antacids
  • Rifampin
  • St. John's Wort

🍽️ Food Interactions

Grapefruit juice increases atorvastatin levels; high-fat meal increases fenofibrate absorption.

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid excessive alcohol.

πŸ›‘οΈ Safety & Warnings

🚫 Contraindications

Active liver disease, unexplained LFT elevations, pregnancy, lactation, hypersensitivity, severe renal impairment.

πŸ“Š Monitoring Parameters

Lipid profile, LFTs, CPK, renal function, INR if on warfarin.

🀱 Lactation Safety

Contraindicated; excreted in milk.

πŸ’Š Overdose Management

Supportive care; monitor liver and renal function; no specific antidote.

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip if close.

πŸ‘¨β€βš•οΈ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

πŸ”— View Profile

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