alvikoff dx syrup - Phenylephrine (5mg) + Chlorpheniramine Maleate (2mg) medicine

alvikoff dx syrup - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Alvio Pharma ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is alvikoff dx syrup used for?

Ascoril D Plus Syrup Sugar Free (Phenylephrine + Chlorpheniramine Maleate) is used to treat RESPIRATORY. It contains Phenylephrine (5mg) + Chlorpheniramine Maleate (2mg), which Phenylephrine: alpha-1 adrenergic agonist causing vasoconstriction; Chlorphenira. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Phenylephrine + Chlorpheniramine Maleate
  • Manufacturer: Alvio Pharma
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š alvikoff dx syrup Uses & Benefits

Allergic rhinitis, Common cold, Sinusitis

๐Ÿ“‹ Drug Information

Generic Name(s)Phenylephrine + Chlorpheniramine Maleate
Brand NameAscoril D Plus Syrup Sugar Free
ManufacturerAlvio Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassDecongestant + Antihistamine
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract
DistributionDistributes widely; crosses blood-brain barrier
Protein BindingPhenylephrine: low; Chlorpheniramine: 70%
MetabolismPhenylephrine: hepatic (MAO); Chlorpheniramine: hepatic (CYP450)
Half-LifePhenylephrine: 2-3 hours; Chlorpheniramine: 12-15 hours
ExcretionRenal (urine)
BioavailabilityPhenylephrine: ~38%; Chlorpheniramine: ~25-50%
Onset of ActionPhenylephrine: 15-30 min; Chlorpheniramine: 30-60 min
Peak Plasma TimePhenylephrine: 1-2 hours; Chlorpheniramine: 2-6 hours
Duration of ActionPhenylephrine: 4-6 hours; Chlorpheniramine: 4-6 hours

How It Works

Phenylephrine: alpha-1 adrenergic agonist causing vasoconstriction; Chlorpheniramine: H1 receptor antagonist blocking histamine effects

Mechanism Steps

1Phenylephrine binds to alpha-1 adrenergic receptors on vascular smooth muscle
2Causes vasoconstriction in nasal mucosa, reducing congestion
3Chlorpheniramine blocks H1 receptors on blood vessels and respiratory epithelium

๐Ÿ’ก How to Take alvikoff dx syrup

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of alvikoff dx syrup

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Nausea
  • Dizziness
  • Headache

๐Ÿšจ Serious Side Effects

  • Hypertension
  • Arrhythmias
  • Seizures
  • Urinary retention

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Thrombocytopenia
  • Hallucinations

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

๐Ÿšจ Major Interactions

  • MAOIs
  • Beta-blockers
  • Tricyclic antidepressants

โšก Moderate Interactions

  • Antihypertensives
  • Sympathomimetics
  • CNS depressants

โ„น๏ธ Minor Interactions

  • Antacids
  • Caffeine

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase chlorpheniramine levels

๐Ÿท Alcohol Interaction

Increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypertension, Hyperthyroidism, Diabetes, Glaucoma, MAOI use, Severe coronary artery disease

๐Ÿ“Š Monitoring Parameters

Blood pressure, Heart rate, CNS effects

๐Ÿคฑ Lactation Safety

Caution; may be excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; may include activated charcoal, benzodiazepines for seizures

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

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