alvotin 10 cp capsule - Uses, Price, Side Effects & Substitutes
What is alvotin 10 cp capsule used for?
Aztolet 10 Tablet (Atorvastatin + Clopidogrel) is used to treat CARDIAC. It contains Atorvastatin (10mg) + Clopidogrel (75mg), which Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Clopido. Always consult your doctor before use. Take as prescribed.
- Generic Name: Atorvastatin + Clopidogrel
- Manufacturer: Alvio Pharma
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ alvotin 10 cp capsule Uses & Benefits
Prevention of cardiovascular events in patients with atherosclerosis, acute coronary syndrome, hyperlipidemia
Off-label uses: Stroke prevention in certain high-risk patients
๐ Drug Information
| Generic Name(s) | Atorvastatin + Clopidogrel |
| Brand Name | Aztolet 10 Tablet |
| Manufacturer | Alvio Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG-CoA Reductase Inhibitor + Platelet Aggregation Inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Clopidogrel irreversibly inhibits P2Y12 receptor on platelets, preventing aggregation
Mechanism Steps
๐ก How to Take alvotin 10 cp capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of alvotin 10 cp capsule
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Myalgia
- Nasopharyngitis
๐จ Serious Side Effects
- Rhabdomyolysis
- Hepatotoxicity
- Severe bleeding
- Thrombotic thrombocytopenic purpura
โ ๏ธ Rare Side Effects
- Peripheral neuropathy
- Interstitial lung disease
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Ketoconazole | Major | Increased atorvastatin levels, risk of myopathy |
| Omeprazole | Major | Reduced clopidogrel efficacy |
| Rivaroxaban | Major | Increased bleeding risk |
| NSAIDs | Major | Increased bleeding risk |
| Digoxin | Moderate | Increased digoxin levels |
| Oral contraceptives | Moderate | Increased contraceptive levels |
| Colchicine | Moderate | Increased risk of myopathy |
| Fibrates | Moderate | Increased risk of myopathy |
| Antacids | Minor | Reduced absorption of atorvastatin |
| Vitamin K antagonists (low dose) | Minor | Minimal interaction |
๐จ Major Interactions
- Warfarin
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP2C19 inhibitors (e.g., omeprazole)
- Anticoagulants (e.g., rivaroxaban)
- NSAIDs
โก Moderate Interactions
- Digoxin
- Oral contraceptives
- Colchicine
- Fibrates
โน๏ธ Minor Interactions
- Antacids
- Vitamin K antagonists (low dose)
๐ฝ๏ธ Food Interactions
Grapefruit juice increases atorvastatin levels; avoid high-fat meals with clopidogrel
๐ท Alcohol Interaction
May increase liver enzyme levels; moderate consumption advised
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active liver disease, pregnancy, breastfeeding, hypersensitivity, active bleeding (for clopidogrel)
๐ Monitoring Parameters
Liver function tests, lipid profile, bleeding time, renal function
๐คฑ Lactation Safety
Not recommended; may pass into breast milk
๐ Overdose Management
Symptomatic and supportive; no specific antidote
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double