alviroz cv 10mg/75mg capsule - Uses, Price, Side Effects & Substitutes
What is alviroz cv 10mg/75mg capsule used for?
Advastat CV 10 Capsule (Rosuvastatin + Clopidogrel) is used to treat CARDIAC. It contains Rosuvastatin (10mg) + Clopidogrel (75mg), which Rosuvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis; Clopid. Always consult your doctor before use. Take as prescribed.
- Generic Name: Rosuvastatin + Clopidogrel
- Manufacturer: Alvio Pharma
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ alviroz cv 10mg/75mg capsule Uses & Benefits
Secondary prevention of atherosclerotic cardiovascular events, acute coronary syndrome, hyperlipidemia with antiplatelet therapy.
Off-label uses: Peripheral artery disease, stroke prevention in high-risk patients.
๐ Drug Information
| Generic Name(s) | Rosuvastatin + Clopidogrel |
| Brand Name | Advastat CV 10 Capsule |
| Manufacturer | Alvio Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antiplatelet + HMG-CoA Reductase Inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Rosuvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis; Clopidogrel: Irreversibly blocks P2Y12 receptor on platelets, inhibiting ADP-induced platelet aggregation.
Mechanism Steps
๐ก How to Take alviroz cv 10mg/75mg capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of alviroz cv 10mg/75mg capsule
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Diarrhea
- Myalgia
- Rash
๐จ Serious Side Effects
- Rhabdomyolysis
- Hepatotoxicity
- Severe bleeding
- Thrombotic thrombocytopenic purpura
โ ๏ธ Rare Side Effects
- Interstitial lung disease
- Pancreatitis
- Angioedema
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Omeprazole | Major | Reduced clopidogrel efficacy |
| Ketoconazole | Major | Increased rosuvastatin levels |
| Rivaroxaban | Major | Increased bleeding risk |
| Ibuprofen | Major | Increased bleeding risk |
| Glipizide | Moderate | Possible hypoglycemia |
| Rifampin | Moderate | Reduced clopidogrel efficacy |
| Digoxin | Moderate | Increased digoxin levels |
| Antacids | Minor | Reduced rosuvastatin absorption |
| Colchicine | Minor | Increased myopathy risk |
๐จ Major Interactions
- Warfarin
- CYP2C19 inhibitors (e.g., omeprazole)
- CYP3A4 inhibitors (e.g., ketoconazole)
- Anticoagulants (e.g., rivaroxaban)
- NSAIDs (e.g., ibuprofen)
โก Moderate Interactions
- CYP2C9 substrates (e.g., glipizide)
- CYP2C19 inducers (e.g., rifampin)
- Statins (increased myopathy risk)
- Digoxin
โน๏ธ Minor Interactions
- Antacids
- Colchicine
- Fenofibrate
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase rosuvastatin levels; avoid high-fat meals with clopidogrel.
๐ท Alcohol Interaction
Avoid excessive alcohol; may increase hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active bleeding, severe liver disease, pregnancy, lactation, hypersensitivity to components.
๐ Monitoring Parameters
Lipid profile, liver function tests, renal function, bleeding signs, platelet function.
๐คฑ Lactation Safety
Not recommended; avoid breastfeeding.
๐ Overdose Management
Supportive care; no specific antidote; consider gastric lavage.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.