alviroz asp 75mg/10mg capsule - Uses, Price, Side Effects & Substitutes
What is alviroz asp 75mg/10mg capsule used for?
Arvast-A 75 Capsule (Rosuvastatin + Aspirin) is used to treat CARDIAC. It contains Rosuvastatin (75mg) + Aspirin (10mg), which Rosuvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Aspirin. Always consult your doctor before use. Take as prescribed.
- Generic Name: Rosuvastatin + Aspirin
- Manufacturer: Alvio Pharma
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ alviroz asp 75mg/10mg capsule Uses & Benefits
Primary and secondary prevention of cardiovascular events in patients with hyperlipidemia and risk of thrombosis.
Off-label uses: None well-established.
๐ Drug Information
| Generic Name(s) | Rosuvastatin + Aspirin |
| Brand Name | Arvast-A 75 Capsule |
| Manufacturer | Alvio Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG-CoA Reductase Inhibitor + Antiplatelet Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Rosuvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Aspirin irreversibly inhibits cyclooxygenase (COX-1), reducing thromboxane A2 and platelet aggregation.
Mechanism Steps
๐ก How to Take alviroz asp 75mg/10mg capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of alviroz asp 75mg/10mg capsule
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Dyspepsia
- Myalgia
- Constipation
๐จ Serious Side Effects
- Rhabdomyolysis
- Hepatotoxicity
- Gastrointestinal bleeding
- Hemorrhagic stroke
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Interstitial lung disease
- Pancreatitis
- Thrombocytopenia
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Cyclosporine | Major | Increased rosuvastatin levels |
| Gemfibrozil | Major | Increased risk of myopathy |
| Clopidogrel | Major | Increased bleeding risk |
| Antacids | Moderate | Reduced rosuvastatin absorption |
| Fibrates | Moderate | Increased risk of myopathy |
| Niacin | Moderate | Increased risk of myopathy |
| Digoxin | Moderate | Possible increased digoxin levels |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Vitamin K antagonists | Minor | Minor INR changes |
| Colchicine | Minor | Increased risk of myopathy |
| Fenofibrate | Minor | Minor interaction |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Cyclosporine
- Gemfibrozil
- Clopidogrel
โก Moderate Interactions
- Antacids
- Fibrates
- Niacin
- Digoxin
- ACE inhibitors
โน๏ธ Minor Interactions
- Vitamin K antagonists
- Colchicine
- Fenofibrate
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase rosuvastatin levels; food delays aspirin absorption.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding with aspirin.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active peptic ulcer, bleeding disorders, hypersensitivity, pregnancy, severe hepatic impairment, concomitant cyclosporine.
๐ Monitoring Parameters
Lipid profile, liver function tests, renal function, INR if on warfarin, signs of bleeding.
๐คฑ Lactation Safety
Not recommended; aspirin excreted in milk, rosuvastatin unknown.
๐ Overdose Management
Supportive care; for aspirin overdose, gastric lavage, activated charcoal, and alkalinization; for rosuvastatin, no specific antidote.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.