Anadol P 37.5mg/325mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Slow, shallow breathing or difficulty breathing
- Seizures or convulsions
- Severe allergic reaction (swelling of face, lips, tongue, or throat)
- Yellowing of skin or eyes, dark urine, or severe abdominal pain
- Extreme drowsiness or difficulty staying awake
- Confusion, agitation, hallucinations, or rapid heart rate
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is altranova tablet used for?
This medicine is a combination of tramadol and paracetamol used for short-term relief of moderate to severe acute pain. It works by reducing pain signals in the brain and spinal cord. It should be taken exactly as prescribed, usually every 4-6 hours, and should not be used for more than a few days without medical advice.
- Generic Name: Tramadol + Paracetamol
- Manufacturer: Astranova Biotech
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 altranova tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ट्रामाडोल और पैरासिटामोल का संयोजन है, जिसका उपयोग मध्यम से गंभीर तीव्र दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह सर्जरी, दांत निकालने, या मस्कुलोस्केलेटल चोट के बाद होने वाले दर्द में प्रभावी है। यह दवा दर्द को कम करने के लिए मस्तिष्क और रीढ़ की हड्डी में दर्द संकेतों को अवरुद्ध करती है। इसका उपयोग केवल डॉक्टर के निर्देशानुसार ही करें और निर्धारित अवधि से अधिक न लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, चक्कर आना, नींद आना, कब्ज, सिरदर्द और मुंह सूखना शामिल हैं। गंभीर दुष्प्रभावों में सांस लेने में कठिनाई, दौरे, गंभीर एलर्जी प्रतिक्रिया, और लीवर की क्षति के लक्षण जैसे त्वचा या आंखों का पीला पड़ना शामिल हैं। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसके साथ शराब का सेवन बिल्कुल न करें। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, तब तक वाहन न चलाएं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको लीवर या किडनी की बीमारी है, तो डॉक्टर को बताएं। इस दवा को बच्चों की पहुंच से दूर रखें।
💊 altranova tablet Uses & Benefits
[{"condition":"Acute moderate to severe pain","description":"This medicine is indicated for the short-term management of moderate to moderately severe acute pain, such as postoperative pain, dental pain, or musculoskeletal injury pain, when non-opioid analgesics are insufficient.","evidence":"Well-established"},{"condition":"Postoperative pain","description":"Used for relief of pain following surgical procedures, often as part of multimodal analgesia.","evidence":"Well-established"},{"condition":"Dental pain","description":"Effective for managing moderate to severe dental pain, including after tooth extraction or other oral surgical procedures.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"May be used for short-term relief of moderate to severe musculoskeletal pain, such as back pain or sprains, when other treatments are inadequate.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Neuropathic pain","description":"Sometimes prescribed off-label for neuropathic pain conditions, though evidence is limited and other agents are preferred.","evidence":"Limited"},{"condition":"Chronic pain","description":"Rarely used off-label for chronic pain management, but not recommended due to risks of dependence and lack of long-term efficacy data.","evidence":"Limited"}]
Primary treatment for: Acute moderate to severe pain
Also treats: Postoperative pain, Dental pain, Musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Tramadol + Paracetamol |
| Brand Name | Anadol P |
| Manufacturer | Astranova Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Opioid analgesic + Non-opioid analgesic |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture, heat, and direct sunlight. Store in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two analgesics with complementary mechanisms. Tramadol is a centrally acting opioid analgesic that binds to mu-opioid receptors and also inhibits the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. Paracetamol acts primarily in the central nervous system to reduce pain and fever, likely by inhibiting prostaglandin synthesis and modulating pain perception. Together, they provide synergistic pain relief.
Mechanism Steps
💡 How to Take altranova tablet
Strength: Tablet containing Tramadol 37.5 mg and Paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally every 4 to 6 hours as needed for pain relief, not to exceed the maximum daily dose. The maximum daily dose is typically 8 tablets in 24 hours, but this may vary based on individual patient factors. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is not recommended for children under 12 years of age. Consult a pediatrician for appropriate pain management in children. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of tramadol, especially respiratory depression, sedation, and confusion. The dose should be reduced and titrated carefully. It is recommended to start with a lower dose and monitor closely. Consult a doctor for individualized dosing. |
| Renal Impairment | In patients with renal impairment, dose reduction and prolongation of dosing interval are recommended. For creatinine clearance less than 30 mL/min, the dosing interval should be increased to every 12 hours, and the maximum daily dose should not exceed 2 tablets. Consult a doctor for specific dose adjustments. |
| Hepatic Impairment | In patients with hepatic impairment, dose reduction is recommended. For severe hepatic impairment, this medicine is contraindicated. For mild to moderate impairment, the dosing interval should be increased, and the maximum daily dose should not exceed 2 tablets. Consult a doctor for specific dose adjustments. |
| Maximum Daily Dose | The maximum daily dose is 8 tablets (300 mg tramadol and 2600 mg paracetamol) in 24 hours. However, the actual maximum dose may be lower based on individual patient factors and should be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of altranova tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Warfarin | Major | |
| SSRIs/SNRIs | Major | |
| Other opioids | Major | |
| Carbamazepine | Moderate | |
| Quinidine | Moderate | |
| Ritonavir | Moderate | |
| Diuretics | Moderate | |
| Anticholinergics | Minor | |
| Metoclopramide | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Other opioids or central nervous system depressants
- Warfarin
- Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs)
⚡ Moderate Interactions
- Carbamazepine
- Quinidine
- Ritonavir
- Diuretics
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Combining alcohol with tramadol and paracetamol increases the risk of severe respiratory depression, excessive sedation, liver damage, and potentially fatal overdose. Even small amounts of alcohol can enhance the central nervous system depressant effects and increase the risk of seizures.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to tramadol, paracetamol, or any component of the formulation","Severe respiratory depression or acute or severe bronchial asthma","Concurrent use or within 14 days of monoamine oxidase inhibitors","Children under 12 years of age","Post-operative management in children under 18 years following tonsillectomy and/or adenoidectomy","Severe hepatic impairment","Known or suspected gastrointestinal obstruction, including paralytic ileus"]
⚠️ Warnings & Precautions
["Risk of respiratory depression, especially in elderly, debilitated, or those with respiratory conditions.","Risk of seizures, particularly in patients with a history of seizures, head trauma, or metabolic disorders.","Risk of serotonin syndrome when used with other serotonergic drugs.","Risk of physical and psychological dependence and withdrawal syndrome with prolonged use.","Risk of hepatotoxicity with paracetamol, especially with alcohol use or exceeding recommended dose.","May impair mental and physical abilities required for driving or operating machinery.","Use with caution in patients with renal or hepatic impairment; dose adjustment may be needed.","Not recommended for use in pregnancy or breastfeeding unless clearly needed."]
🤱 Lactation Safety
Tramadol and paracetamol are excreted in breast milk. Tramadol is not recommended during breastfeeding due to the risk of serious adverse reactions in the infant, including excessive sleepiness, breathing difficulties, and withdrawal symptoms. Paracetamol is considered compatible with breastfeeding. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe respiratory depression, seizures, liver toxicity, and potentially death. If overdose is suspected, seek emergency medical attention immediately. Treatment includes supportive care, maintenance of airway and breathing, and administration of naloxone for opioid toxicity. For paracetamol toxicity, N-acetylcysteine is the antidote and should be given as soon as possible. Activated charcoal may be considered if within 1-2 hours of ingestion. Monitor liver and renal function closely.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid alcohol completely while taking this medicine, as it can increase the risk of serious side effects including respiratory depression and liver damage. Do not drive or operate heavy machinery until you know how this medicine affects you, as it may cause drowsiness or dizziness. Inform your doctor if you have a history of liver or kidney disease, seizures, breathing problems, or substance abuse. Do not take this medicine with other products containing paracetamol to avoid exceeding the maximum daily dose and risking liver injury. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children and store it in its original container at room temperature, away from moisture and heat. Do not share this medicine with anyone else, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of tramadol, including respiratory depression, sedation, and confusion. The dose should be reduced and titrated carefully. It is recommended to start with a lower dose and monitor closely for side effects. Consult a doctor for individualized dosing.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Tramadol is not recommended during pregnancy due to potential risks to the fetus. Discuss alternative pain management options with your healthcare provider.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery for pain management. It should be used for the shortest duration possible. Monitor for side effects such as respiratory depression and sedation. Follow your surgeon's instructions for pain control and gradually reduce the dose as you recover.
🦷 Dental Procedures
This medicine can be used for dental pain after procedures like tooth extraction. Inform your dentist about all medications you are taking. Do not take additional paracetamol-containing products to avoid exceeding the maximum daily dose.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid activities that require mental alertness or physical coordination, such as driving or operating machinery, until you know how it affects you. Exercise may be beneficial for pain management, but start slowly and avoid overexertion. Consult your doctor or physical therapist for guidance on safe exercises.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, dizziness, and impaired coordination, which can affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. Avoid these activities until you know how the medicine affects you. Inform your employer if your job requires such activities. Take breaks and rest as needed.
🛑 When to Stop This Medicine
Stop taking this medicine when your pain is adequately controlled or as advised by your doctor. Do not stop abruptly after prolonged use; consult your doctor for a tapering schedule to avoid withdrawal symptoms. If you experience any serious side effects, stop the medicine and seek medical attention immediately.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to tolerance, physical dependence, and withdrawal symptoms upon discontinuation. It may also increase the risk of liver damage due to paracetamol and worsen kidney function. Prolonged use should be avoided, and regular monitoring of liver and kidney function is recommended if extended use is necessary. Consult your doctor regularly to assess the need for continued therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve function.
Evidence: Well-establishedMay help with certain types of pain, but evidence is mixed.
Evidence: LimitedHelps manage chronic pain by changing thought patterns and behaviors.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. This medicine is a controlled substance in many countries, so check local regulations before traveling internationally. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing intervals as advised by your doctor. Do not pack it in checked luggage; keep it in your carry-on bag.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30-60 minutes after taking it orally.
A: Pain relief typically lasts for about 4-6 hours, so dosing is usually every 4-6 hours as needed.
A: Yes, you can take it with or without food, but taking it with food may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus. Consult your doctor if you are pregnant or planning to become pregnant.
A: No, alcohol should be completely avoided as it increases the risk of serious side effects including respiratory depression and liver damage.
🤔 Common Patient Concerns
🔄 Substitutes for altranova tablet
View AllAlternative brands with exact same active ingredient:
-
dolram plus 37.5mg/325mg tabletZeelab Pharmacy Pvt Ltd ₹22.50 56.4% CHEAPER
-
Tramgesic 37.5mg/325mg TabletChiron Pharmaceuticals Pvt Ltd ₹27.88 45.9% CHEAPER
-
stayhappi tramadol+paracetamol 37.5mg/325mg tabletSarvagunaushdhi Pvt Ltd ₹28.13 45.4% CHEAPER
-
novadol p 37.5mg/325mg tabletRadicura Pharma pvt ltd ₹32.81 36.4% CHEAPER
-
Trombodol P 37.5mg/325mg TabletCogniwell Pharmaceuticals Private Limited ₹32.81 36.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe to take for long periods.
Fact: This medicine is intended for short-term use only. Prolonged use can lead to dependence, tolerance, and other serious side effects. - Myth: It is okay to drink alcohol while taking this medicine.
Fact: Alcohol should be completely avoided as it increases the risk of respiratory depression, liver damage, and sedation. - Myth: This medicine can be taken by children.
Fact: This medicine is not recommended for children under 12 years of age due to safety concerns. - Myth: You can stop this medicine abruptly after long-term use.
Fact: Abrupt discontinuation after prolonged use can cause withdrawal symptoms. Always consult your doctor for a tapering schedule.
🔄 Alternative Options
Generic Alternatives
- Tramadol 37.5 mg + Paracetamol 325 mg tablet
Brand Alternatives
- Ultracet
- Tramacet
- Zydol
- Contramal