alphadex 100mcg injection - Uses, Price, Side Effects & Substitutes
What is alphadex 100mcg injection used for?
Alphadex 100mcg Injection (Dexmedetomidine) is used to treat NEURO CNS. It contains Dexmedetomidine (100mcg), which Selective alpha-2 adrenergic receptor agonist, reducing sympathetic outflow and . Always consult your doctor before use. Take as prescribed.
- Generic Name: Dexmedetomidine
- Manufacturer: Fusion Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ alphadex 100mcg injection Uses & Benefits
Sedation of intubated and mechanically ventilated patients in ICU, procedural sedation, adjunct to anesthesia.
Off-label uses: Treatment of opioid withdrawal, prevention of delirium, pediatric sedation.
๐ Drug Information
| Generic Name(s) | Dexmedetomidine |
| Brand Name | Alphadex 100mcg Injection |
| Manufacturer | Fusion Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Alpha 2-Adrenoceptor agonists (Anaesthetic) |
| Route of Administration | Intravenous infusion; also intramuscular. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Selective alpha-2 adrenergic receptor agonist, reducing sympathetic outflow and inducing sedation, analgesia, and anxiolysis.
Mechanism Steps
๐ก How to Take alphadex 100mcg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of alphadex 100mcg injection
โ Common Side Effects
- Bradycardia
- Hypotension
- Dry mouth
- Nausea
- Vomiting
๐จ Serious Side Effects
- Severe bradycardia
- Cardiac arrest
- Hypotension requiring intervention
- Atrial fibrillation
โ ๏ธ Rare Side Effects
- Hyperthermia
- Seizures
- Prolonged QT interval
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Sevoflurane | Major | Enhanced sedation and bradycardia |
| Fentanyl | Major | Increased risk of bradycardia and hypotension |
| Propranolol | Major | Additive bradycardia and hypotension |
| Midazolam | Moderate | Additive sedation |
| Atropine | Moderate | May counteract bradycardia |
| Caffeine | Minor | May reduce sedative effect |
๐จ Major Interactions
- Anesthetics (e.g., sevoflurane, isoflurane)
- Opioids (e.g., fentanyl, morphine)
- Antihypertensives (e.g., beta-blockers, clonidine)
โก Moderate Interactions
- Sedatives (e.g., benzodiazepines, barbiturates)
- Anticholinergics (e.g., atropine)
- Vasodilators (e.g., nitroglycerin)
โน๏ธ Minor Interactions
- Caffeine
- Theophylline
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Enhanced sedative effects; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to dexmedetomidine, advanced heart block (unless paced), severe hypotension, acute cerebrovascular disease.
๐ Monitoring Parameters
Heart rate, blood pressure, respiratory rate, oxygen saturation, sedation level (e.g., Richmond Agitation-Sedation Scale).
๐คฑ Lactation Safety
Not recommended; excreted in animal milk, unknown in humans.
๐ Overdose Management
Supportive care; atropine for bradycardia, fluids and vasopressors for hypotension.
โฐ Missed Dose
Administer as soon as possible; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for alphadex 100mcg injection
View AllAlternative brands with exact same active ingredient (Dexmedetomidine (100mcg)):
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dexmedine injectionSamarth Life Sciences Pvt Ltd โน226.46 22.9% CHEAPER
-
dexit 100mcg injectionTroikaa Pharmaceuticals Ltd โน338.14 15.2% COSTLIER
-
xamdex 100mcg injectionAbbott โน356.25 21.3% COSTLIER
-
medetofix 100 injectionVarenyam Healthcare Pvt Ltd โน540.00 83.9% COSTLIER
-
dexglan 100mcg injectionGland Pharma Limited โน555.00 89% COSTLIER
-
dexem 100mcg injectionThemis Medicare Ltd โน646.80 120.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.