aloval 300mg tablet cr - Sodium Valproate (300mg) medicine

aloval 300mg tablet cr - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Enrico Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is aloval 300mg tablet cr used for?

Arkaval 200mg Tablet (Sodium Valproate) is used to treat NEURO CNS. It contains Sodium Valproate (300mg), which Increases GABA levels in the brain by inhibiting GABA transaminase and enhancing. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Sodium Valproate
  • Manufacturer: Enrico Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š aloval 300mg tablet cr Uses & Benefits

Epilepsy (generalized and partial seizures), Bipolar disorder (mania), Migraine prophylaxis

Off-label uses: Neuropathic pain, Post-traumatic stress disorder, Aggression in dementia

๐Ÿ“‹ Drug Information

Generic Name(s)Sodium Valproate
Brand NameArkaval 200mg Tablet
ManufacturerEnrico Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSodium channel modulators (AED)
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC); protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.
DistributionDistributes widely throughout the body; crosses the blood-brain barrier and placenta.
Protein BindingApproximately 90% bound to plasma proteins, mainly albumin.
MetabolismExtensively metabolized in the liver via glucuronidation and beta-oxidation; also involves CYP450 enzymes (CYP2C9, CYP2A6).
Half-Life9-16 hours (may be longer in neonates, elderly, or liver disease).
ExcretionPrimarily renal (as metabolites); less than 3% excreted unchanged.
BioavailabilityApproximately 100% (oral).
Onset of Action1-2 hours (therapeutic effect may take days to weeks).
Peak Plasma Time1-4 hours (extended-release: 4-17 hours).
Duration of ActionVariable; typically 8-12 hours for immediate-release formulations.

How It Works

Increases GABA levels in the brain by inhibiting GABA transaminase and enhancing GABA synthesis; also blocks voltage-gated sodium channels and T-type calcium channels.

Mechanism Steps

1Inhibits GABA transaminase, reducing GABA breakdown.
2Increases glutamic acid decarboxylase activity, enhancing GABA synthesis.
3Blocks voltage-gated sodium channels, stabilizing neuronal membranes.

๐Ÿ’ก How to Take aloval 300mg tablet cr

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aloval 300mg tablet cr

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Drowsiness
  • Tremor
  • Weight gain
  • Hair loss
  • Thrombocytopenia

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Pancreatitis
  • Hyperammonemic encephalopathy
  • Stevens-Johnson syndrome
  • Bone marrow suppression
  • Teratogenicity

โš ๏ธ Rare Side Effects

  • Polycystic ovary syndrome
  • Reversible hearing loss
  • Vasculitis
  • Enuresis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Carbamazepine Major Decreased valproate levels; increased carbamazepine toxicity.
Lamotrigine Major Increased risk of Stevens-Johnson syndrome; lamotrigine levels increased.
Phenytoin Major Altered phenytoin levels; increased valproate toxicity.
Warfarin Moderate Increased bleeding risk.
Aspirin Moderate Increased valproate levels and toxicity.

๐Ÿšจ Major Interactions

  • Carbamazepine
  • Lamotrigine
  • Phenytoin
  • Phenobarbital
  • Rifampin
  • Topiramate

โšก Moderate Interactions

  • Aspirin
  • Warfarin
  • Cimetidine
  • Erythromycin
  • Felbamate
  • Fluoxetine

โ„น๏ธ Minor Interactions

  • Antacids
  • Charcoal
  • Cholestyramine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not affect extent; avoid grapefruit juice (theoretical).

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS depression and hepatotoxicity risk.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to valproate, Active liver disease, Significant hepatic dysfunction, Urea cycle disorders, Porphyria

๐Ÿ“Š Monitoring Parameters

Liver function tests, Complete blood count, Serum valproate levels (therapeutic: 50-100 mcg/mL), Ammonia levels if symptoms of hyperammonemia

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised; benefits may outweigh risks.

๐Ÿ’Š Overdose Management

Supportive care; activated charcoal if recent ingestion; hemodialysis may be considered; naloxone ineffective.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for aloval 300mg tablet cr

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Alternative brands with exact same active ingredient (Sodium Valproate (300mg)):

Medical Note: Always consult your doctor before switching medications.

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