alles d tablet - Levocetirizine (5mg) + Phenylephrine (25mg) medicine

Alles D Tablet: Complete Medicine Guide

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🏭 Destin Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for allergic rhinitis; limited for common cold.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat
  • Chest pain or irregular heartbeat
  • Severe headache with blurred vision
  • Difficulty breathing
  • Unusual bleeding or bruising
  • Seizures

If experiencing severe symptoms, call emergency services immediately.

What is alles d tablet used for?

This medicine is a combination of levocetirizine (an antihistamine) and phenylephrine (a decongestant) used for short-term relief of allergy symptoms and nasal congestion. It is taken orally, usually once or twice daily, and should not be used for more than 7 days without medical advice.

  • Generic Name: Levocetirizine + Phenylephrine
  • Manufacturer: Destin Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alles d tablet के बारे में (Hindi Summary)

उपयोग: यह दवा लेवोसेटिरिज़िन और फेनिलएफ्रिन का संयोजन है, जिसका उपयोग एलर्जी राइनाइटिस, सर्दी-जुकाम और नाक बंद होने के लक्षणों से राहत के लिए किया जाता है। यह छींक, बहती नाक, खुजली और आंखों में पानी आने को कम करती है। यह दवा अल्पकालिक उपयोग के लिए है और इसे डॉक्टर की सलाह के बिना 7 दिनों से अधिक नहीं लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, सिरदर्द, थकान और जी मिचलाना शामिल हैं। कुछ लोगों को दिल की धड़कन तेज होना या बेचैनी महसूस हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, या सीने में दर्द हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। निर्धारित मात्रा से अधिक न लें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या मशीनरी चलाने से बचें। इस दवा के साथ शराब न पिएं। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड की समस्या या प्रोस्टेट बढ़ा हुआ है, तो अपने डॉक्टर को बताएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 alles d tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal itching associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold with nasal congestion","description":"Provides temporary relief of nasal stuffiness and allergy symptoms when both are present.","evidence":"Established for short-term use"},{"condition":"Vasomotor rhinitis","description":"May help reduce nasal congestion and sneezing in non-allergic rhinitis.","evidence":"Limited"}]

Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used to relieve congestion and allergic symptoms in acute or chronic sinusitis, but not a primary treatment.","evidence":"Limited"},{"condition":"Otitis media with effusion","description":"Occasionally used for symptomatic relief of nasal congestion in children, but evidence is weak.","evidence":"Insufficient"}]

Primary treatment for: Allergic rhinitis

Also treats: Common cold, Vasomotor rhinitis, Sinusitis

📋 Drug Information

Generic Name(s)Levocetirizine + Phenylephrine
Brand NameAllercet Cold Tablet
ManufacturerDestin Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Decongestant
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food if it causes stomach upset.
2
Avoid driving or operating machinery until you know how it affects you.
3
Do not take this medicine for more than 7 days without consulting your doctor.
4
Monitor your blood pressure if you have hypertension.
5
Stay well hydrated throughout the day.
6
Do not combine with other antihistamines or decongestants without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing and runny nose
This medicine is commonly prescribed for these symptoms.
Likely Use
✅
Nasal congestion
Phenylephrine helps relieve nasal stuffiness.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Body ache
This medicine is not indicated for body pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevocetirizine is rapidly and extensively absorbed after oral administration. Phenylephrine is absorbed from the gastrointestinal tract but undergoes significant first-pass metabolism, resulting in low oral bioavailability.
DistributionLevocetirizine is widely distributed throughout the body. Phenylephrine distribution is not well characterized but is expected to distribute into tissues.
Protein BindingLevocetirizine is approximately 90% bound to plasma proteins. Protein binding of phenylephrine is not established from the available information.
MetabolismLevocetirizine undergoes minimal metabolism in the liver. Phenylephrine is extensively metabolized in the liver and gut wall by monoamine oxidase and sulfotransferases.
Half-LifeThe elimination half-life of levocetirizine is approximately 6 to 8 hours in adults with normal kidney function. The half-life of phenylephrine is not established from the available information.
ExcretionLevocetirizine is primarily excreted unchanged in the urine. Phenylephrine and its metabolites are excreted mainly in the urine.
BioavailabilityLevocetirizine oral bioavailability is high, approximately 90% or more. Phenylephrine oral bioavailability is low and variable due to first-pass metabolism.
Onset of ActionLevocetirizine begins to relieve allergy symptoms within 1 hour. Phenylephrine nasal decongestion may start within 15 to 30 minutes.
Peak Plasma TimeLevocetirizine reaches peak plasma concentration in about 0.5 to 1 hour. Peak plasma time for phenylephrine is not established from the available information.
Duration of ActionLevocetirizine provides relief for about 24 hours. Phenylephrine decongestant effect lasts about 4 to 6 hours.

How It Works

This medicine combines two active ingredients with complementary actions. Levocetirizine is the active enantiomer of cetirizine and works as a selective peripheral H1-receptor antagonist. It prevents histamine from binding to H1 receptors on blood vessels and nerve endings, reducing allergy symptoms such as sneezing, itching, and runny nose. Phenylephrine is a direct-acting sympathomimetic amine that selectively stimulates alpha-1 adrenergic receptors on nasal blood vessels, causing vasoconstriction and reducing swelling of the nasal mucosa. The combination provides both antihistaminic and decongestant effects.

Mechanism Steps

1
Histamine H1 receptor blockade: Levocetirizine binds to H1 receptors on cells in the respiratory tract and blood vessels, preventing histamine from triggering allergic symptoms.
2
Reduction of allergic inflammation: By blocking H1 receptors, levocetirizine decreases vasodilation, capillary permeability, and sensory nerve activation, which reduces sneezing, itching, and runny nose.
3
Alpha-1 adrenergic receptor stimulation: Phenylephrine stimulates alpha-1 receptors on nasal mucosal blood vessels, causing them to constrict.
4
Nasal decongestion: Vasoconstriction reduces blood flow and swelling in the nasal passages, temporarily relieving congestion and improving breathing.

💡 How to Take alles d tablet

Strength: Levocetirizine 5 mg + Phenylephrine 25 mg immediate-release tablet.

1Take this medicine orally with a glass of water.
2Swallow the tablet whole. Do not crush or chew.
3Take with or without food, but if stomach upset occurs, take with a meal.
4Take at the same time each day to maintain consistent levels.
5Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once or twice daily as directed by your doctor. The exact dose and frequency depend on your condition, age, and kidney function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially drowsiness and cardiovascular effects. Dose adjustment may be needed based on renal function. Consult a doctor.
Renal ImpairmentIn patients with renal impairment, dose reduction of levocetirizine is recommended. Consult a doctor for appropriate dose adjustment.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is one tablet twice daily, but this must be confirmed by a doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals if stomach upset occurs
Reduces gastrointestinal discomfort.
Grapefruit
Avoid excessive intake
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alles d tablet

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you. Consult doctor if persistent.
Dry mouth (Common (5-10%))
Sip water frequently. Usually resolves on its own.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe or persistent.
Fatigue (Common (5-10%))
Get adequate rest. Consult doctor if it interferes with daily activities.
Nausea (Uncommon (1-5%))
Take with food. Consult doctor if it continues.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or rash.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Seek immediate medical attention if you feel palpitations, chest pain, or shortness of breath.
Severe hypertension (Rare (<0.1%))
Seek immediate medical attention if you experience severe headache, blurred vision, or chest pain.

⚠️ Rare Side Effects

Seizures
Seek emergency medical help immediately.
Blood disorders (e.g., thrombocytopenia)
Consult doctor if you notice unusual bleeding or bruising.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Beta-blockers Major
Tricyclic antidepressants Major
Alcohol Moderate
Antihypertensives Moderate
Digoxin Moderate
Antacids Minor
Cimetidine Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Beta-blockers
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines)
  • Antihypertensives
  • Digoxin

🍷 Alcohol Interaction

Alcohol can increase drowsiness and impair motor skills when taken with this medicine. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to levocetirizine, phenylephrine, or any component of the formulation","Severe hypertension or uncontrolled high blood pressure","Severe coronary artery disease","Uncontrolled hyperthyroidism","Use within 14 days of stopping MAO inhibitors","Severe renal impairment (for levocetirizine component)"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not exceed the recommended dose.","Use with caution in patients with cardiovascular disease, diabetes, or prostate enlargement.","Do not use for more than 7 days without consulting a doctor.","Avoid alcohol while taking this medicine.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Levocetirizine may pass into breast milk and could cause drowsiness in the infant. Phenylephrine may reduce breast milk production. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, agitation, hypertension, or irregular heartbeat. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not drink alcohol while taking this medicine because it can increase drowsiness. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, or prostate enlargement. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. Store at room temperature away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to drowsiness and cardiovascular effects. Dose adjustment may be needed based on renal function. Monitor blood pressure regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy if you are taking this medicine. It is not recommended during pregnancy unless clearly needed.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, especially if you are taking other medications or have cardiovascular concerns.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Avoid known allergens such as dust, pollen, and pet dander.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Wash bedding regularly in hot water.
💧
Stay hydrated to thin nasal secretions.
🧘
Get adequate rest to support immune function.

🏋️ Exercise Considerations

This medicine may cause drowsiness or increase heart rate. Avoid strenuous exercise until you know how it affects you.

🥗 Diet Recommendations

Include vitamin C-rich foods like oranges and bell peppers.
Reduce intake of processed foods and added sugars.
Stay well hydrated with water and warm fluids.
Avoid alcohol while taking this medicine.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also cause dry mouth, so keep water handy.

🛑 When to Stop This Medicine

Stop this medicine if you experience severe side effects such as allergic reactions, irregular heartbeat, or severe headache. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of decongestants like phenylephrine can lead to rebound congestion. Regular monitoring of blood pressure and renal function may be needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps clear nasal passages and reduce congestion without medication.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can decrease the need for medication.

Evidence: Well-established
Intranasal corticosteroid sprays

Effective for allergic rhinitis but require prescription.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Consult your doctor if you are due for vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergic rhinitis
She started this medicine as prescribed for sneezing and nasal congestion. Within 2 days, her symptoms improved significantly. She experienced mild drowsiness initially but it subsided. She was advised to avoid driving until she knew the effects.
💡 Lesson: This medicine provides effective short-term relief but may cause drowsiness. Avoid driving until you know how it affects you.
👤 A 50-year-old man with hypertension and cold symptoms
He was prescribed this medicine for nasal congestion. His blood pressure was monitored closely because phenylephrine can raise blood pressure. He was advised to use it for only 3 days and to report any headache or palpitations.
💡 Lesson: Patients with high blood pressure should use this medicine with caution and under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Levocetirizine starts working within 1 hour, and phenylephrine may relieve congestion within 15-30 minutes.

Q: Can I take it at night?

A: Yes, but it may cause drowsiness. If it makes you sleepy, taking it at night may be helpful.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my blood pressure?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure allergies permanently.
    Fact: This medicine only provides symptomatic relief. It does not cure allergies.
  • Myth: It is safe to take every day for months.
    Fact: It should be used short-term unless advised by a doctor. Long-term use requires medical supervision.
  • Myth: It is safe for everyone.
    Fact: It is not safe for people with certain heart conditions, severe hypertension, or those taking MAOIs.

🔄 Alternative Options

Generic Alternatives

  • Levocetirizine + Phenylephrine generic tablets

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Levocetirizine 5 mg + Phenylephrine 25 mg","onset":"1 hour","duration":"24 hours for antihistamine; 4-6 hours for decongestant","sedation":"Mild"},{"medicine":"Cetirizine + Pseudoephedrine","composition":"Cetirizine 5 mg + Pseudoephedrine 120 mg","onset":"1 hour","duration":"24 hours","sedation":"Mild"}]

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