allcid d 10mg/20mg tablet - Domperidone (10mg) + Omeprazole (20mg) medicine

Aciloc RD 20 Tablet: Complete Medicine Guide

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🏭 Biocore Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain or palpitations
  • Difficulty breathing or swelling of face, lips, or throat
  • Blood in vomit or black, tarry stools
  • Severe abdominal pain or persistent vomiting
  • Yellowing of skin or eyes
  • Unusual muscle cramps or tremors
  • Signs of allergic reaction like rash or itching

If experiencing severe symptoms, call emergency services immediately.

What is allcid d 10mg/20mg tablet used for?

This medicine is a combination of Domperidone and Omeprazole used to treat acid reflux, heartburn, and nausea by reducing stomach acid and improving gastric emptying. It is taken orally once daily before breakfast.

  • Generic Name: Domperidone + Omeprazole
  • Manufacturer: Biocore Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 allcid d 10mg/20mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डोम्पेरिडोन और ओमेप्राज़ोल का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, हार्टबर्न, अपच और मतली के इलाज के लिए किया जाता है। यह पेट में एसिड को कम करती है और पेट खाली होने की प्रक्रिया को तेज करती है। इसे सुबह नाश्ते से 30 मिनट पहले खाली पेट लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, सिरदर्द, दस्त, पेट दर्द और मतली शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन दिल की धड़कन अनियमित होना, एलर्जी, या स्तन में दर्द हो सकता है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे नाश्ते से 30 मिनट पहले खाली पेट लें। गोली को चबाएं या तोड़ें नहीं। शराब का सेवन न करें। अगर आपको चक्कर या नींद आती है तो वाहन न चलाएं। दिल, लीवर या किडनी की बीमारी हो तो डॉक्टर को बताएं।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 allcid d 10mg/20mg tablet Uses & Benefits

[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces acid reflux and heartburn by suppressing stomach acid and improving gastric emptying.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Helps heal ulcers by reducing acid secretion and promoting gastric motility.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Relieves symptoms like bloating, early satiety, and upper abdominal discomfort.","evidence":"Moderate"},{"condition":"Nausea and vomiting associated with gastroparesis","description":"Domperidone component helps reduce nausea and vomiting by improving stomach emptying.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Diabetic gastroparesis","description":"Sometimes prescribed off-label to improve gastric emptying in diabetic patients.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease (GERD)

Also treats: Peptic ulcer disease, Functional dyspepsia, Gastroparesis, Nausea and vomiting

📋 Drug Information

Generic Name(s)Domperidone + Omeprazole
Brand NameAciloc RD 20 Tablet
ManufacturerBiocore Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProkinetic agent + Proton pump inhibitor
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at least 30 minutes before breakfast on an empty stomach for best results.
2
Do not crush or chew the tablet; swallow it whole with water.
3
Avoid alcohol and grapefruit juice while taking this medicine.
4
If you have heart problems, inform your doctor before starting this medicine.
5
Do not take this medicine for more than 12 weeks without a medical review.
6
Report any unusual muscle cramps, palpitations, or skin rash to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Heartburn
This medicine is commonly prescribed for this.
Likely Use
Acid regurgitation
This medicine helps reduce acid reflux.
Likely Use
Nausea
Domperidone component helps relieve nausea.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDomperidone is rapidly absorbed after oral administration, with peak plasma levels occurring within 30-60 minutes. Omeprazole is also rapidly absorbed, with peak plasma concentrations achieved within 1-2 hours. Food may delay the absorption of omeprazole but does not significantly affect the extent of absorption.
DistributionDomperidone is widely distributed in the body but does not readily cross the blood-brain barrier. Omeprazole is distributed extensively into tissues, including the gastric mucosa. Both drugs have moderate volumes of distribution.
Protein BindingDomperidone is approximately 91-93% bound to plasma proteins. Omeprazole is about 95% bound to plasma proteins.
MetabolismDomperidone undergoes extensive first-pass metabolism in the liver via CYP3A4 and CYP1A2 enzymes. Omeprazole is metabolized in the liver primarily by CYP2C19 and CYP3A4 enzymes.
Half-LifeDomperidone: approximately 7-9 hours; Omeprazole: approximately 0.5-1 hour.
ExcretionDomperidone is excreted mainly in feces (about 66%) and urine (about 33%). Omeprazole metabolites are excreted primarily in urine (about 80%) and feces (about 20%).
BioavailabilityDomperidone: about 15% due to first-pass metabolism; Omeprazole: about 30-40% after a single dose, increasing with repeated dosing.
Onset of ActionDomperidone: within 30-60 minutes; Omeprazole: within 1 hour for acid suppression, but full effect may take 1-4 days.
Peak Plasma TimeDomperidone: 0.5-1 hour; Omeprazole: 1-2 hours.
Duration of ActionDomperidone: 4-6 hours; Omeprazole: up to 24 hours for acid suppression.

How It Works

This medicine combines two active ingredients with complementary actions. Domperidone is a peripheral dopamine D2 receptor antagonist that blocks dopamine receptors in the chemoreceptor trigger zone and the gastrointestinal tract, leading to increased gastric motility and accelerated gastric emptying. Omeprazole is a proton pump inhibitor that irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, thereby suppressing both basal and stimulated gastric acid secretion. The combination provides both acid suppression and prokinetic effects, addressing multiple aspects of upper gastrointestinal disorders.

Mechanism Steps

1
Domperidone blocks dopamine D2 receptors: Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone and the gastrointestinal tract, which reduces nausea and enhances gastric motility.
2
Omeprazole inhibits proton pumps: Omeprazole irreversibly binds to the H+/K+ ATPase enzyme in gastric parietal cells, blocking the final step of acid secretion.
3
Combined effect on upper GI function: The combination leads to reduced acid exposure and improved gastric emptying, alleviating symptoms of GERD, dyspepsia, and nausea.

💡 How to Take allcid d 10mg/20mg tablet

Strength: Tablet containing Domperidone 10 mg and Omeprazole 20 mg.

1Take the tablet at least 30 minutes before breakfast on an empty stomach.
2Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.
3If you forget to take it before breakfast, take it as soon as you remember, but not with food.
4Do not take antacids within 2 hours of this medicine.
5Follow your doctor's instructions regarding duration and dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once daily, preferably 30 minutes before breakfast on an empty stomach. However, the dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and clinical response. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially cardiac effects and risk of fractures. Dose adjustment may be necessary based on renal and hepatic function. Consult your doctor.
Renal ImpairmentDose adjustment may be required in patients with severe renal impairment. Consult your doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (Domperidone 10 mg + Omeprazole 20 mg) per day. Do not exceed this dose without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Before breakfast
Take on an empty stomach
Improves absorption and efficacy of omeprazole.
High-fat meals
Avoid taking with them
May delay absorption and reduce effectiveness.
Grapefruit juice
Avoid
May increase omeprazole levels and side effects.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of allcid d 10mg/20mg tablet

✅ Common Side Effects

Dry mouth (Common (1-10%))
Sip water frequently or chew sugar-free gum. Consult doctor if persistent.
Headache (Common (1-10%))
Rest and stay hydrated. If severe or persistent, consult your doctor.
Diarrhea (Common (1-10%))
Stay hydrated. Avoid fatty or spicy foods. Consult doctor if it lasts more than 2 days.
Abdominal pain (Common (1-10%))
Take with food if advised. If pain is severe, contact your doctor.
Nausea (Common (1-10%))
Take the tablet as prescribed. If nausea persists, consult your doctor.

🚨 Serious Side Effects

Irregular heartbeat (QT prolongation) (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, dizziness, or fainting.
Allergic reaction (rash, swelling, difficulty breathing) (Rare (<0.1%))
Stop the medicine and seek emergency medical help immediately.
Breast tenderness or discharge (galactorrhea) (Uncommon (0.1-1%))
Consult your doctor; dose adjustment or alternative may be needed.
Low magnesium levels (hypomagnesemia) (Rare (<0.1%) with long-term use)
Report muscle cramps, tremors, or irregular heartbeat to your doctor.

⚠️ Rare Side Effects

Severe skin reactions (Stevens-Johnson syndrome)
Seek immediate medical attention if you develop a painful rash with blisters or peeling skin.
Liver dysfunction
Report yellowing of eyes or skin, dark urine, or severe fatigue to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Clopidogrel Major
Warfarin Moderate
Methotrexate Moderate
Digoxin Moderate
Antacids Minor
Iron supplements Minor
Rifampicin Moderate
St. John's Wort Moderate
Fluconazole Moderate

🚨 Major Interactions

  • Ketoconazole, itraconazole, clarithromycin, ritonavir
  • QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)
  • Clopidogrel

⚡ Moderate Interactions

  • Warfarin
  • Methotrexate
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach irritation and worsen drowsiness caused by domperidone. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to domperidone or omeprazole","Gastrointestinal obstruction, perforation, or bleeding","Prolactin-releasing pituitary tumor (prolactinoma)","Severe liver impairment","Concomitant use with strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)","Known QT prolongation or family history of sudden cardiac death"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart disease or electrolyte imbalances.","Avoid in patients with Parkinson's disease as domperidone may worsen symptoms.","Long-term use of omeprazole may increase risk of bone fractures, especially in elderly.","May mask symptoms of stomach cancer; rule out malignancy before starting.","Do not use for more than 12 weeks without medical review.","Use with caution in patients with kidney or liver disease."]

🤱 Lactation Safety

Domperidone passes into breast milk and may cause side effects in the infant. Omeprazole is also excreted in breast milk. Consult your doctor before breastfeeding while on this medicine.

💊 Overdose Management

Overdose may cause drowsiness, disorientation, extrapyramidal symptoms, and QT prolongation. Seek immediate medical attention. Treatment is symptomatic and supportive. ECG monitoring is recommended. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with water. It is best taken on an empty stomach, at least 30 minutes before breakfast, but follow your doctor's specific instructions. Avoid alcohol while taking this medicine as it can worsen stomach irritation and increase drowsiness. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have heart problems, liver disease, or kidney disease. Do not take this medicine for longer than recommended without medical review. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of bone fractures, low magnesium, and vitamin B12 deficiency with long-term use. Dose adjustment may be needed based on kidney and liver function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established, and alternative treatments may be considered.

🏥 Post-Surgery Considerations

After surgery, use this medicine only if prescribed by your surgeon. It may affect healing and interact with other postoperative medications. Inform your surgeon about all medicines you are taking.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase the risk of bleeding during dental procedures. Your dentist may recommend precautions.

💚 Lifestyle Tips for Better Results

🏃
Eat smaller, more frequent meals to reduce acid reflux.
🥗
Avoid spicy, fatty, and acidic foods that trigger heartburn.
😴
Maintain a healthy weight to reduce pressure on the stomach.
💧
Elevate the head of your bed while sleeping to prevent night-time reflux.
🧘
Avoid lying down immediately after eating.
🌞
Quit smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Moderate exercise is generally safe, but avoid vigorous exercise immediately after meals as it may worsen reflux. If you experience dizziness or palpitations, stop and consult your doctor.

🥗 Diet Recommendations

Include fiber-rich foods like fruits and vegetables.
Choose lean proteins and whole grains.
Avoid caffeine, chocolate, and mint, which can relax the lower esophageal sphincter.
Stay hydrated by drinking water throughout the day.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not significantly impact your ability to work if you follow precautions.

🛑 When to Stop This Medicine

Do not stop this medicine abruptly without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping. Long-term use should be reviewed periodically.

📅 Long-Term Use Effects

Long-term use of this medicine, especially omeprazole, may lead to low magnesium levels, vitamin B12 deficiency, increased risk of bone fractures, and possibly kidney problems. Regular monitoring and periodic review by your doctor are recommended. Do not use for more than 12 weeks without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary and lifestyle modifications

Avoiding trigger foods, eating smaller meals, and losing weight can reduce reflux symptoms.

Evidence: Well-established
Other acid-suppressing medicines

H2 blockers like ranitidine or other proton pump inhibitors may be alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before any vaccination if you are on long-term acid suppression.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight and moisture

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, continue taking it at your usual time or adjust as advised by your doctor. Keep it in your carry-on luggage to avoid loss.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with chronic acid reflux
He was prescribed this medicine for persistent heartburn and regurgitation. After taking it daily before breakfast for two weeks, his symptoms significantly improved. He also reduced spicy food and caffeine intake.
💡 Lesson: Consistent use on an empty stomach and dietary modifications lead to better symptom control.
👤 A 60-year-old woman with diabetic gastroparesis
She experienced nausea and early satiety. Her doctor prescribed this medicine. Within a week, her nausea reduced and she could eat better. She was advised to monitor her blood sugar regularly.
💡 Lesson: This medicine can help with gastroparesis symptoms, but underlying conditions like diabetes need ongoing management.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief from nausea and heartburn within 1-2 days, but full acid suppression may take up to 4 weeks.

Q: Can I take it with food?

A: It is best taken on an empty stomach, at least 30 minutes before breakfast. Food may reduce its effectiveness.

Q: Is it safe during pregnancy?

A: Consult your doctor. The safety of this combination during pregnancy is not well established, and it should be used only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for allcid d 10mg/20mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken anytime with food.
    Fact: It should be taken on an empty stomach, at least 30 minutes before breakfast, for best effect.
  • Myth: It is safe to take indefinitely.
    Fact: Long-term use should be monitored by a doctor due to potential side effects.

🔄 Alternative Options

Generic Alternatives

  • Domperidone + Omeprazole combination generics

Brand Alternatives

  • Aciloc RD 20 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Domperidone + Omeprazole","composition":"Domperidone 10 mg + Omeprazole 20 mg","onset":"30-60 minutes","duration":"Up to 24 hours","notes":"Combines prokinetic and acid-suppressing actions."},{"medicine":"Pantoprazole + Domperidone","composition":"Pantoprazole 40 mg + Domperidone 10 mg","onset":"1-2 hours","duration":"Up to 24 hours","notes":"Similar action; pantoprazole has fewer drug interactions."}]

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