alkalith 450mg tablet cr - Uses, Price, Side Effects & Substitutes
What is alkalith 450mg tablet cr used for?
Alkalith 450mg tablet CR (Lithium carbonate) is used to treat NEURO CNS. It contains Lithium carbonate (450mg), which Modulates neurotransmitter release; inhibits inositol monophosphatase; alters G-. Always consult your doctor before use. Take as prescribed.
- Generic Name: Lithium carbonate
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ alkalith 450mg tablet cr Uses & Benefits
Bipolar disorder (mania and maintenance), augmentation in depression
Off-label uses: Cluster headaches, neutropenia, hyperthyroidism (rare)
๐ Drug Information
| Generic Name(s) | Lithium carbonate |
| Brand Name | Alkalith 450mg tablet CR |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Mood stabilizers |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Modulates neurotransmitter release; inhibits inositol monophosphatase; alters G-protein signaling
Mechanism Steps
๐ก How to Take alkalith 450mg tablet cr
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of alkalith 450mg tablet cr
โ Common Side Effects
- Nausea
- Diarrhea
- Tremor
- Polyuria
- Polydipsia
- Weight gain
- Fatigue
๐จ Serious Side Effects
- Lithium toxicity (ataxia, confusion, seizures)
- Arrhythmias
- Renal impairment
- Hypothyroidism
โ ๏ธ Rare Side Effects
- Pseudotumor cerebri
- Hyperparathyroidism
- Nephrogenic diabetes insipidus
- Leukocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| NSAIDs | Major | Increased lithium levels and toxicity risk |
| Thiazide diuretics | Major | Increased lithium reabsorption, elevated levels |
| ACE inhibitors | Major | Decreased lithium excretion, increased toxicity |
| SSRIs | Moderate | Increased risk of serotonin syndrome |
| Caffeine | Minor | May decrease lithium levels |
๐จ Major Interactions
- NSAIDs
- ACE inhibitors
- Thiazide diuretics
- Metronidazole
- Carbamazepine
โก Moderate Interactions
- SSRIs
- Verapamil
- Methyldopa
- Topiramate
โน๏ธ Minor Interactions
- Caffeine
- Theophylline
- Sodium bicarbonate
๐ฝ๏ธ Food Interactions
Sodium intake affects lithium levels; avoid low-sodium diets
๐ท Alcohol Interaction
May increase CNS depression; avoid excessive alcohol
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Severe renal impairment, severe cardiovascular disease, untreated hypothyroidism, low sodium levels
๐ Monitoring Parameters
Serum lithium levels (therapeutic 0.6-1.2 mEq/L), renal function, thyroid function, ECG
๐คฑ Lactation Safety
Excreted in breast milk; monitor infant for toxicity
๐ Overdose Management
Gastric lavage, whole bowel irrigation, hemodialysis for severe toxicity; supportive care
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for alkalith 450mg tablet cr
View AllAlternative brands with exact same active ingredient (Lithium carbonate (450mg)):
-
zecarb 450mg tablet srZeus Pharma โน17.23 5% COSTLIER
-
a lith 450mg tablet srPifer Pharmaceuticals Pvt Ltd โน19.69 20% COSTLIER
-
lithowel 450mg tablet crSigmund Promedica โน22.76 38.7% COSTLIER
-
t lith 450mg tablet crTripada Biotec Pvt Ltd โน23.75 44.7% COSTLIER
-
carcare 450mg tablet srCurelogic Pharma โน27.19 65.7% COSTLIER
-
lithon 450mg tablet srRKG Pharma โน29.51 79.8% COSTLIER
-
litca 450mg tablet srD D Pharmaceuticals โน35.20 114.5% COSTLIER
-
lithicab 450mg tablet srTas Med India Pvt Ltd โน35.61 117% COSTLIER
-
intalith cr 450 tabletIntas Pharmaceuticals Ltd โน36.00 119.4% COSTLIER
-
Trilith 450mg Tablet SRTriton Healthcare Pvt Ltd โน37.62 129.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.