alkacit syrup - Disodium Hydrogen Citrate (1.4gm/5ml) medicine

Alkasol Oral Solution: Complete Guide to Uses, Dosage, and Safety

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🏭 Ortin Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for urinary alkalinization and prevention of uric acid stones.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling in your legs, ankles, or sudden weight gain
  • Muscle twitching, cramps, or spasms
  • Confusion or difficulty concentrating
  • Irregular or fast heartbeat
  • Severe nausea or vomiting
  • Blood in urine or severe pain in the flank
  • Difficulty breathing or chest pain
  • Signs of allergic reaction such as rash, itching, or swelling of face or throat

If experiencing severe symptoms, call emergency services immediately.

What is alkacit syrup used for?

This medicine is an oral solution of disodium hydrogen citrate used to make urine less acidic. It helps relieve burning during urinary tract infections and prevents uric acid and cystine kidney stones. It works by neutralizing acid in the urine.

  • Generic Name: Disodium Hydrogen Citrate
  • Manufacturer: Ortin Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alkacit syrup के बारे में (Hindi Summary)

उपयोग: यह दवा मुख्य रूप से मूत्र मार्ग के संक्रमण (यूटीआई) में जलन और दर्द को कम करने के लिए दी जाती है। यह पेशाब को कम अम्लीय बनाती है, जिससे बार-बार पेशाब आने और जलन में आराम मिलता है। इसके अलावा, यह यूरिक एसिड और सिस्टीन की पथरी को घोलने और बनने से रोकने में मदद करती है। गाउट के मरीजों में यह पथरी की रोकथाम के लिए भी इस्तेमाल होती है। यह दवा शरीर में अम्ल की मात्रा को संतुलित करने में भी सहायक है।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में हल्का पेट दर्द, जी मिचलाना, दस्त, और मुँह में नमकीन स्वाद शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी पैरों में सूजन, वजन बढ़ना, या इलेक्ट्रोलाइट असंतुलन जैसी गंभीर समस्याएँ हो सकती हैं। अगर आपको सूजन, मांसपेशियों में ऐंठन, भ्रम, या दिल की धड़कन अनियमित लगे, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं के बारे में बताएं, खासकर किडनी, हृदय, या उच्च रक्तचाप की। यह दवा सोडियम युक्त है, इसलिए कम नमक वाले आहार पर रहने वाले लोगों को सावधानी बरतनी चाहिए। इस दवा के साथ एल्युमिनियम युक्त एंटासिड न लें। पर्याप्त पानी पिएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को बच्चों से दूर रखें और निर्देशानुसार ही सेवन करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 alkacit syrup Uses & Benefits

[{"condition":"Urinary tract infections (UTIs)","description":"This medicine helps relieve the burning and irritation of UTIs by making the urine less acidic, which reduces discomfort and creates an environment less favorable for bacterial growth.","evidence":"Well-established"},{"condition":"Uric acid kidney stones","description":"It helps dissolve and prevent the formation of uric acid stones by alkalinizing the urine.","evidence":"Well-established"},{"condition":"Cystine kidney stones","description":"Used to increase urine pH, which helps dissolve cystine stones and prevent their recurrence.","evidence":"Well-established"},{"condition":"Metabolic acidosis","description":"This medicine can help correct mild metabolic acidosis by providing an alkali load.","evidence":"Moderate"},{"condition":"Gout","description":"It is used to alkalinize urine in patients with gout to prevent uric acid stone formation.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Chemotherapy-induced hyperuricemia","description":"Sometimes used to prevent uric acid nephropathy in patients receiving chemotherapy, though allopurinol and rasburicase are more definitive.","evidence":"Limited"},{"condition":"Rhabdomyolysis","description":"May be used to alkalinize urine in rhabdomyolysis to prevent kidney damage from myoglobin, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Urinary tract infections

Also treats: Uric acid kidney stones, Cystine kidney stones, Gout, Metabolic acidosis

📋 Drug Information

Generic Name(s)Disodium Hydrogen Citrate
Brand NameAlkasol Oral Solution
ManufacturerOrtin Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassUricosuric agent-gout
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep the bottle tightly closed. Do not freeze.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or after meals to reduce stomach upset.
2
Drink plenty of water throughout the day to help flush your urinary system.
3
Monitor your urine pH if advised by your doctor, especially if you are taking it for kidney stones.
4
Avoid taking aluminum-containing antacids within 2 hours of this medicine.
5
If you have high blood pressure or heart failure, inform your doctor before taking this medicine due to its sodium content.
6
Do not exceed the prescribed dose, as it can lead to metabolic alkalosis.
7
Report any signs of swelling, muscle twitching, or irregular heartbeat to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Burning during urination
This medicine is commonly prescribed to relieve this symptom.
Likely Use
Frequent urination
It helps reduce urgency and frequency by alkalinizing urine.
Likely Use
Fever
This medicine is not a primary fever reducer. Fever may indicate infection requiring antibiotics.
Not Primary
Flank pain
Severe flank pain may indicate kidney stones or infection; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDisodium hydrogen citrate is absorbed from the gastrointestinal tract. The citrate component is rapidly absorbed and metabolized. The exact bioavailability is not established from the available information.
DistributionCitrate is widely distributed in the body as it is a normal constituent of cellular metabolism. It enters the citric acid cycle and is distributed to tissues. Specific volume of distribution data is not established from the available information.
Protein BindingNot established from the available information.
MetabolismCitrate is metabolized in the liver and other tissues via the citric acid cycle to bicarbonate, carbon dioxide, and water. It does not undergo significant cytochrome P450 metabolism.
Half-LifeThe elimination half-life of citrate is short, typically less than 30 minutes, as it is rapidly metabolized. However, the effect on urine pH lasts longer. Specific half-life values are not established from the available information.
ExcretionThe bicarbonate produced from citrate metabolism is excreted primarily in the urine, where it exerts its alkalinizing effect. Some citrate may also be excreted unchanged in urine. Carbon dioxide is eliminated through the lungs.
BioavailabilityNot established from the available information.
Onset of ActionThe effect on urine pH typically begins within 1 to 2 hours after oral administration, but the full therapeutic effect may take several doses to achieve.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe alkalinizing effect on urine lasts for several hours, depending on the dose and individual factors. Typically, the effect lasts 4 to 6 hours after a single dose.

How It Works

This medicine works by providing citrate ions that are metabolized in the body to bicarbonate. Bicarbonate is an alkali that neutralizes excess acid in the urine, raising the urinary pH. This alkalinization helps relieve the burning sensation of urinary tract infections by reducing the acidity of urine that irritates the bladder lining. It also increases the solubility of uric acid and cystine, preventing them from forming crystals and stones in the urinary tract. Additionally, by making the urine less acidic, it creates an environment that is less favorable for the growth of certain bacteria.

Mechanism Steps

1
Ingestion and absorption: Disodium hydrogen citrate is taken orally and absorbed from the gastrointestinal tract.
2
Metabolism to bicarbonate: In the body, citrate is metabolized to bicarbonate, which acts as an alkali.
3
Alkalinization of urine: Bicarbonate is excreted in the urine, where it neutralizes excess hydrogen ions, raising the urinary pH.
4
Therapeutic effects: The increased urine pH reduces bladder irritation, increases solubility of uric acid and cystine, and creates an environment less favorable for bacterial growth.

💡 How to Take alkacit syrup

Strength: Oral solution containing disodium hydrogen citrate 1.4 grams per 5 ml.

1Shake the bottle well before each use.
2Measure the prescribed dose using a measuring cup or spoon provided.
3Take the medicine orally, with or without food, but preferably with food to reduce stomach upset.
4Drink a full glass of water after taking the medicine.
5Follow your doctor's instructions regarding frequency and duration.
6Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5 to 10 ml taken 3 to 4 times daily, depending on the condition being treated. For urinary tract infections, it is often taken every 4 to 6 hours. For kidney stones, the dose may be adjusted to maintain urine pH in the desired range. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially regarding fluid retention and electrolyte imbalances. Dose should be individualized by a qualified clinician, and kidney function should be monitored.
Renal ImpairmentUse with caution in patients with kidney disease. Dose adjustment may be necessary based on kidney function. Consult a doctor for individualized dosing.
Hepatic ImpairmentNo specific dose adjustment is established for liver disease. Use with caution in patients with severe liver disease.
Maximum Daily DoseThe maximum daily dose should not exceed 40 ml per day, unless otherwise directed by a doctor. Individual dosing must be determined by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
High-sodium foods
Limit
This medicine contains sodium; excess sodium can worsen fluid retention.
Water
Drink plenty
Helps flush the urinary system and supports the medicine's effect.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alkacit syrup

✅ Common Side Effects

Mild stomach upset (Common (5-10%))
Take with food or after meals to reduce stomach irritation. If it persists, consult your doctor.
Nausea (Common (5-10%))
Take with a small snack or after meals. If nausea continues, talk to your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or persistent, contact your doctor.
Salty taste (Common (5-10%))
This is due to the sodium content. Rinse your mouth after taking the medicine. It usually goes away.
Increased thirst (Uncommon (1-5%))
Drink water as needed. This is usually not a cause for concern.

🚨 Serious Side Effects

Metabolic alkalosis (Rare (<0.1%))
Seek immediate medical attention if you experience confusion, muscle twitching, irregular heartbeat, or severe weakness.
Fluid retention and swelling (Rare (<0.1%))
Contact your doctor if you notice swelling in your legs, ankles, or sudden weight gain.
Hypernatremia (high sodium levels) (Rare (<0.1%))
Seek medical help if you experience extreme thirst, confusion, or seizures.
Allergic reaction (Rare (<0.1%))
Get emergency help if you have rash, itching, swelling of face or throat, or difficulty breathing.

⚠️ Rare Side Effects

Hypokalemia (low potassium)
Report muscle weakness, cramps, or palpitations to your doctor.
Tetany
Seek immediate medical attention if you experience muscle spasms or twitching.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Aluminum-containing antacids Major
Lithium Major
Salicylates Major
Amphetamines Moderate
Quinidine Moderate
Methenamine Moderate
Anticholinergics Minor
Diuretics Minor

🚨 Major Interactions

  • Aluminum-containing antacids
  • Lithium
  • Salicylates (e.g., aspirin)

⚡ Moderate Interactions

  • Amphetamines
  • Quinidine
  • Methenamine

🍷 Alcohol Interaction

Alcohol may increase stomach irritation and worsen dehydration. It is advisable to avoid or limit alcohol while taking this medicine, especially if you have a urinary tract infection or kidney stones.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe kidney disease with reduced urine output","Uncontrolled heart failure","Uncontrolled high blood pressure","Severe liver disease","Active peptic ulcer","Known hypersensitivity to disodium hydrogen citrate or any component","Patients on a strict low-sodium diet","Metabolic alkalosis"]

⚠️ Warnings & Precautions

["This medicine contains sodium; use with caution in patients with hypertension, heart failure, or edema.","Do not take with aluminum-containing antacids due to risk of aluminum toxicity.","Monitor urine pH to ensure appropriate alkalinization; excessive alkalinization can cause metabolic alkalosis.","Use with caution in patients with kidney disease; dose adjustment may be needed.","Not recommended for patients with severe liver disease.","Consult a doctor before use during pregnancy or breastfeeding.","Keep out of reach of children.","Do not exceed the recommended dose.","If symptoms persist or worsen, consult a doctor."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose of this medicine can lead to metabolic alkalosis, hypernatremia, and fluid retention. Symptoms may include confusion, muscle twitching, seizures, and irregular heartbeat. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and may include intravenous fluids, electrolyte correction, and monitoring of vital signs and blood gases. In severe cases, dialysis may be considered.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before taking this medicine, tell your doctor if you have kidney problems, heart failure, high blood pressure, or any condition that requires you to limit salt in your diet. This medicine contains sodium, so it may not be suitable for people on a low-sodium diet. Do not take this medicine with antacids that contain aluminum, as they can interfere with its effect. Drink plenty of water while taking this medicine to help flush your urinary system. Do not change your dose or stop taking this medicine without talking to your doctor first. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Store it at room temperature, away from direct sunlight and moisture. Do not use it after the expiry date printed on the pack. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose. Never double the dose to make up for a missed one.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to electrolyte imbalances and fluid retention. Use this medicine with caution, and monitor kidney function and electrolytes regularly. Dose adjustment may be necessary.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy has not been fully established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

After surgery, use this medicine only if prescribed by your doctor. It may be used to alkalinize urine in certain post-surgical conditions, but monitoring is essential. Inform your surgeon about all medicines you are taking.

🦷 Dental Procedures

This medicine does not typically interfere with dental procedures. However, inform your dentist about all medicines you are taking. If you need to fast for a procedure, ask your doctor about adjusting your dose schedule.

💚 Lifestyle Tips for Better Results

🏃
Drink at least 8-10 glasses of water daily to help flush your urinary system.
🥗
Limit your intake of high-purine foods like red meat, organ meats, and shellfish if you have gout or uric acid stones.
😴
Maintain a healthy weight through balanced diet and regular exercise.
💧
Avoid excessive salt intake, as this medicine contains sodium.
🧘
Practice good hygiene to prevent urinary tract infections.
🌞
Urinate frequently and completely; do not hold urine for long periods.
🚭
Include fruits and vegetables rich in citrate, such as lemons and oranges, in your diet.

🏋️ Exercise Considerations

There are no specific exercise restrictions while taking this medicine. However, if you experience dizziness or muscle cramps due to electrolyte imbalances, avoid strenuous activities and consult your doctor. Stay well hydrated during exercise.

🥗 Diet Recommendations

Drink plenty of water throughout the day.
Limit high-purine foods such as red meat, shellfish, and alcohol.
Reduce sodium intake to prevent fluid retention.
Include citrate-rich fruits like lemons, oranges, and melons.
Eat a balanced diet with plenty of fiber.
Avoid excessive caffeine, which can irritate the bladder.

💼 Impact on Daily Work & Life

This medicine generally does not affect your ability to drive or operate machinery. However, if you experience dizziness, confusion, or muscle weakness due to electrolyte imbalances, avoid these activities and consult your doctor. It may cause frequent urination, so plan accordingly during work or travel.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects such as metabolic alkalosis, fluid retention, or allergic reactions, stop the medicine and seek immediate medical attention. Your doctor will advise you on when to stop based on your condition and test results.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to metabolic alkalosis, electrolyte imbalances such as low potassium, and fluid retention. It may also increase the risk of kidney stones if urine pH becomes too alkaline. Regular monitoring of urine pH, serum electrolytes, and kidney function is recommended. Your doctor may adjust the dose or recommend breaks in treatment based on your response and test results.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Increased water intake

Drinking plenty of water helps dilute urine and flush the urinary system, complementing the effect of this medicine.

Evidence: Well-established
Dietary changes

Reducing purine-rich foods and sodium can help prevent uric acid stones and reduce the need for alkalinizers.

Evidence: Well-established
Potassium citrate

An alternative urinary alkalinizer that may be preferred in patients who need to limit sodium.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, if you are acutely ill with a urinary tract infection, consult your doctor about timing of vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep the bottle tightly closed

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, continue taking your doses at the same intervals as prescribed, but adjust to local time gradually. Keep enough supply for your entire trip. If you are flying, pack it in your carry-on luggage to avoid loss or temperature extremes in checked baggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with recurrent urinary tract infections
She experienced burning and frequent urination. Her doctor prescribed this medicine along with an antibiotic. She took it with meals and drank plenty of water. Within two days, her burning sensation reduced significantly. She completed the full course and felt much better.
💡 Lesson: Taking this medicine with food and staying hydrated improves tolerability and effectiveness.
👤 A 50-year-old man with a history of uric acid kidney stones
He was advised to take this medicine regularly to prevent stone formation. He monitored his urine pH using strips as instructed. His urine pH remained in the target range, and follow-up scans showed no new stones. He also reduced his intake of high-purine foods.
💡 Lesson: Regular monitoring of urine pH and dietary modifications are key to preventing uric acid stones.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 1 to 2 hours after taking a dose, but you may need to take it regularly for a day or two to notice significant relief from symptoms.

Q: Can I take this medicine with other medications?

A: It can interact with certain medicines like aluminum-containing antacids, lithium, and salicylates. Always inform your doctor about all medicines you are taking.

Q: Is it safe to take this medicine during pregnancy?

A: Consult your doctor before taking this medicine during pregnancy. The safety has not been fully established.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose. Do not double dose.

Q: Can I take this medicine for a long time?

A: Long-term use should be monitored by your doctor with regular blood tests to check electrolytes and kidney function.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • How long does it take to work?

🔄 Substitutes for alkacit syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is an antibiotic.
    Fact: This medicine is not an antibiotic. It is a urinary alkalinizer that helps relieve symptoms but does not kill bacteria. Antibiotics may be needed for bacterial infections.
  • Myth: This medicine can cure all types of kidney stones.
    Fact: This medicine is effective only for uric acid and cystine stones. It does not dissolve calcium oxalate stones, which are the most common type.
  • Myth: It is safe to take this medicine indefinitely without monitoring.
    Fact: Long-term use requires monitoring of urine pH and electrolytes to avoid complications like metabolic alkalosis.

🔄 Alternative Options

Generic Alternatives

  • Disodium hydrogen citrate oral solution

Brand Alternatives

  • Alkasol
  • Citralka
  • Disodium hydrogen citrate solution

📊 Comparison with Similar Medicines

[{"medicine":"Disodium hydrogen citrate","class":"Urinary alkalinizer","main_use":"UTI symptom relief, uric acid stones","sodium_content":"High"},{"medicine":"Potassium citrate","class":"Urinary alkalinizer","main_use":"Uric acid stones, metabolic acidosis","sodium_content":"Low"},{"medicine":"Sodium bicarbonate","class":"Antacid, alkalinizer","main_use":"Metabolic acidosis, heartburn","sodium_content":"High"}]

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