alinol 0.25mg/20mg tablet - Alprazolam (0.25mg) + Propranolol (20mg) medicine

Alinol 0.25mg/20mg Tablet - Uses, Price, Side Effects

4.5 (15 reviews)
๐Ÿญ Kivi Labs Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is alinol 0.25mg/20mg tablet used for?

Alinol 0.25mg/20mg Tablet is a combination of Alprazolam and Propranolol used to treat anxiety disorders with physical symptoms like palpitations and trembling. Alprazolam works by enhancing GABA activity to reduce anxiety, while Propranolol blocks beta-adrenergic receptors to lower heart rate and blood pressure, providing comprehensive relief.

  • Generic Name: Alprazolam + Propranolol
  • Manufacturer: Kivi Labs Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š alinol 0.25mg/20mg tablet Uses & Benefits

Anxiety disorders, panic disorder, performance anxiety, essential tremor, situational anxiety

Off-label uses: Insomnia, premenstrual dysphoric disorder, social phobia, migraine prophylaxis

๐Ÿ“‹ Drug Information

Generic Name(s)Alprazolam + Propranolol
Brand NameAmbulax Tablet
ManufacturerKivi Labs Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassBenzodiazepine + Beta-blocker
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely; crosses blood-brain barrier
Protein BindingAlprazolam: 80%; Propranolol: >90%
MetabolismHepatic via CYP3A4 (alprazolam) and CYP2D6 (propranolol)
Half-LifeAlprazolam: 6-12 hours; Propranolol: 3-6 hours
ExcretionRenal (urine)
BioavailabilityAlprazolam: 90%; Propranolol: 25-30%
Onset of ActionAlprazolam: 1-2 hours; Propranolol: 1-2 hours
Peak Plasma TimeAlprazolam: 1-2 hours; Propranolol: 1-4 hours
Duration of ActionAlprazolam: 6-12 hours; Propranolol: 6-12 hours

How It Works

Alprazolam enhances GABA-A receptor activity; Propranolol blocks beta-adrenergic receptors

Mechanism Steps

1Alprazolam binds to benzodiazepine site on GABA-A receptor
2Enhances GABA affinity, increasing chloride ion influx
3Hyperpolarizes neuron, reducing excitability

๐Ÿ’ก How to Take alinol 0.25mg/20mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of alinol 0.25mg/20mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dizziness
  • Fatigue
  • Dry mouth
  • Nausea
  • Constipation
  • Bradycardia
  • Hypotension

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Severe bradycardia
  • Heart block
  • Hypotension
  • Seizures
  • Suicidal thoughts
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Jaundice
  • Agranulocytosis
  • Thrombocytopenia
  • Stevens-Johnson syndrome
  • Bronchospasm

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Major Increased sedation and dizziness
Cimetidine Moderate Increased alprazolam levels
Verapamil Moderate Increased propranolol levels

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP2D6 inhibitors (e.g., quinidine)
  • Other CNS depressants
  • Calcium channel blockers
  • Antiarrhythmics

โšก Moderate Interactions

  • Oral hypoglycemics
  • Theophylline
  • Warfarin
  • Digoxin
  • MAO inhibitors

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Oral contraceptives
  • Antacids

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice (increases alprazolam levels), High-fat meals may delay absorption

๐Ÿท Alcohol Interaction

Avoid; increased CNS depression and sedation

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, acute narrow-angle glaucoma, severe COPD, asthma, bradycardia, heart block, uncompensated heart failure, myasthenia gravis, severe hepatic impairment

๐Ÿ“Š Monitoring Parameters

Heart rate, blood pressure, respiratory rate, sedation level, liver function tests, renal function

๐Ÿคฑ Lactation Safety

Not recommended; both drugs excreted in breast milk

๐Ÿ’Š Overdose Management

Supportive care; flumazenil for alprazolam overdose; atropine, beta-agonists for propranolol overdose

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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