Acrotac 25mg Capsule: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes (jaundice)
- Severe abdominal pain, especially upper abdominal pain that may radiate to the back
- Persistent nausea and vomiting
- Severe headache with blurred or double vision
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing
- Blood in stool or vomit
- Decreased urine output
- Unusual bleeding or bruising
- Severe skin rash or peeling
If experiencing severe symptoms, call emergency services immediately.
What is acipsor 25mg capsule used for?
This medicine is an oral retinoid used to treat severe psoriasis and other skin disorders by slowing down the rapid growth of skin cells. It is a prescription medicine that requires strict monitoring and must be avoided during pregnancy.
- Generic Name: Acitretin
- Manufacturer: Kivi Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acipsor 25mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से गंभीर सोरायसिस (सोरायसिस) और त्वचा के अन्य विकारों के इलाज के लिए इस्तेमाल की जाती है। यह त्वचा की कोशिकाओं के तेजी से बढ़ने को धीमा करती है और त्वचा की परत को सामान्य बनाने में मदद करती है। इसका उपयोग इक्थियोसिस, पामोप्लांटर पस्टुलोसिस और लाइकेन प्लानस जैसी स्थितियों में भी किया जाता है। यह दवा केवल डॉक्टर की सलाह पर ही लेनी चाहिए और गर्भवती महिलाओं को इसका सेवन बिल्कुल नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में होंठों का सूखना, त्वचा का सूखना और पपड़ी बनना, आंखों का सूखना, नाक का सूखना, बालों का झड़ना, सिरदर्द, जोड़ों में दर्द और रक्त में वसा का बढ़ना शामिल है। गंभीर दुष्प्रभावों में लीवर की क्षति, अग्न्याशय की सूजन, और सिर के अंदर दबाव बढ़ना शामिल है। अगर आपको पीलिया, गंभीर पेट दर्द, या दृष्टि में बदलाव दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को केवल त्वचा रोग विशेषज्ञ की देखरेख में ही लें। गर्भवती महिलाएं या जो गर्भवती हो सकती हैं, वे इस दवा का सेवन न करें। महिलाओं को इलाज से पहले, दौरान और बंद करने के तीन साल बाद तक दो विश्वसनीय गर्भनिरोधक तरीकों का इस्तेमाल करना चाहिए। इलाज के दौरान और बंद करने के दो महीने बाद तक शराब का सेवन बिल्कुल न करें। रक्तदान न करें। धूप से बचाव करें और सनस्क्रीन का इस्तेमाल करें। नियमित रूप से लीवर और लिपिड की जांच कराएं।
💊 acipsor 25mg capsule Uses & Benefits
- [{"condition":"Severe plaque psoriasis","description":"This medicine is used to treat severe forms of plaque psoriasis that have not responded to other therapies such as topical treatments, phototherapy, or methotrexate.
- It helps reduce scaling, thickness, and redness of plaques.","evidence":"Well-established"},{"condition":"Palmoplantar pustulosis","description":"This medicine can help clear pustules and reduce thickening on the palms and soles, improving pain and function.","evidence":"Well-established"},{"condition":"Ichthyosis","description":"It is used in various forms of ichthyosis, a group of genetic skin disorders characterized by dry, scaly skin, to reduce scaling and improve skin texture.","evidence":"Well-established"},{"condition":"Lichen planus","description":"This medicine may be prescribed for severe lichen planus, a condition causing itchy, purplish skin bumps and oral lesions, when other treatments fail.","evidence":"Moderate"},{"condition":"Darier disease","description":"It can be used to manage Darier disease, a genetic disorder causing rough, bumpy skin, by reducing keratinization abnormalities.","evidence":"Moderate"},{"condition":"Pityriasis rubra pilaris","description":"This medicine is sometimes used to treat pityriasis rubra pilaris, a rare skin disorder with reddish-orange scaling, especially in severe cases.","evidence":"Limited"}]
Off-label uses: [{"condition":"Cutaneous lupus erythematosus","description":"Occasionally used off-label for severe skin lupus when other treatments are ineffective or not tolerated.","evidence":"Limited"},{"condition":"Lichen sclerosus","description":"May be used off-label for severe lichen sclerosus, a chronic inflammatory skin condition, in selected patients.","evidence":"Limited"},{"condition":"Sarcoidosis with skin involvement","description":"Rarely used off-label for skin sarcoidosis that does not respond to standard therapies.","evidence":"Limited"}]
Primary treatment for: Severe plaque psoriasis
Also treats: Palmoplantar pustulosis, Ichthyosis, Lichen planus, Darier disease, Pityriasis rubra pilaris
📋 Drug Information
| Generic Name(s) | Acitretin |
| Brand Name | Acrotac 25mg Capsule |
| Manufacturer | Kivi Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Retinoids- Second generation |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C (59°F to 86°F). Protect it from light and moisture. Keep it in the original container, tightly closed. Do not store it in the bathroom. Keep out of reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Check the expiry date on the pack before use. Do not use it after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to and activating retinoic acid receptors and retinoid X receptors in the nucleus of skin cells. This activation changes the way certain genes are expressed, which slows down the excessive production of skin cells and promotes normal differentiation. It also reduces inflammation in the skin by affecting immune cells and cytokine production. The result is a decrease in scaling, thickening, and redness of psoriatic plaques and other keratinization disorders.
Mechanism Steps
💡 How to Take acipsor 25mg capsule
Strength: This medicine is available as an immediate-release capsule containing 25 mg of acitretin.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 25 mg to 50 mg once daily, taken with food. Your doctor may start with a lower dose and gradually increase it based on your response and tolerability. The maximum recommended dose is 50 mg per day for most conditions, but some patients may require up to 75 mg per day under close supervision. The dose must be individualized by a qualified clinician based on the indication, severity of the condition, age, weight, liver and kidney function, and other medicines you are taking. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician or dermatologist for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dry skin, dry eyes, and bone changes. The dose should be selected with caution, and regular monitoring of liver function, lipid levels, and bone health is recommended. The dose must be individualized by a qualified clinician. |
| Renal Impairment | This medicine should be used with caution in patients with kidney disease. Dose adjustment may be necessary in severe renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | This medicine is contraindicated in patients with severe liver disease. In patients with mild to moderate liver impairment, dose reduction may be necessary, and liver function should be monitored closely. The dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 50 mg for most indications, but some patients may require up to 75 mg per day under close specialist supervision. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acipsor 25mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | |
| Tetracyclines | Major | |
| Vitamin A | Major | |
| Alcohol | Major | |
| Phenytoin | Moderate | |
| Oral contraceptives | Moderate | |
| Corticosteroids | Moderate | |
| Glyburide | Moderate | |
| St. John's wort | Moderate | |
| Progestin-only contraceptives | Minor |
🚨 Major Interactions
- Methotrexate
- Tetracyclines (e.g., doxycycline, minocycline)
- Vitamin A or other retinoids
- Alcohol
- Phenytoin
⚡ Moderate Interactions
- Oral contraceptives (combined hormonal contraceptives)
- Corticosteroids
- Glyburide (glibenclamide)
- St. John's wort
🍷 Alcohol Interaction
Alcohol must be completely avoided while taking this medicine and for at least two months after stopping. Alcohol can increase the risk of liver damage and can cause this medicine to be converted into etretinate, a substance that remains in the body for a very long time and can cause severe birth defects. Even small amounts of alcohol can be harmful.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy or women who may become pregnant during treatment or within three years after stopping.","Breastfeeding.","Severe liver disease or significantly elevated liver enzymes.","Severe kidney disease.","Uncontrolled high blood cholesterol or triglycerides.","Known hypersensitivity to acitretin or any component of the formulation.","Concurrent use of tetracyclines, methotrexate, or vitamin A supplements.","Inability to comply with strict pregnancy prevention measures."]
⚠️ Warnings & Precautions
["This medicine can cause severe birth defects. Women must use two reliable forms of contraception and undergo regular pregnancy testing.","Do not donate blood during treatment or for three years after stopping, as the medicine can be passed to a pregnant recipient.","Avoid alcohol completely during treatment and for two months after stopping.","This medicine can increase blood lipid levels. Monitor lipid profile and manage appropriately.","This medicine can cause liver injury. Monitor liver function tests regularly.","This medicine can increase sensitivity to sunlight. Use sunscreen and protective clothing.","This medicine may cause dry eyes and decreased night vision. Use caution when driving at night.","Long-term use may cause bone changes. Monitor for bone pain and consider bone density testing.","This medicine may interact with other medicines. Inform your doctor about all medicines you take.","Do not take vitamin A supplements or other retinoids while taking this medicine."]
🤱 Lactation Safety
This medicine is excreted in breast milk and can cause serious adverse effects in a nursing infant. Breastfeeding is contraindicated while taking this medicine. Women should not breastfeed during treatment and for at least three years after stopping.
💊 Overdose Management
Overdose of this medicine may cause severe headache, nausea, vomiting, drowsiness, and increased intracranial pressure. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if the overdose is recent. Monitor vital signs and neurological status.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
This medicine is a powerful prescription medicine and must only be taken under the supervision of a dermatologist or other qualified specialist. Never share this medicine with anyone else, even if they have similar symptoms. Women of childbearing potential must use two reliable forms of contraception for at least one month before starting treatment, during treatment, and for three years after the last dose. Pregnancy must be ruled out with a negative test before starting and monthly during treatment. Do not donate blood while taking this medicine or for three years after stopping, because the medicine can be passed to a pregnant recipient. Avoid alcohol completely during treatment and for two months after stopping, as alcohol can increase the risk of liver damage and may convert this medicine into a form that stays in the body longer. Do not take vitamin A supplements or other retinoid medicines without your doctor's approval. Use sunscreen and protective clothing because this medicine can make your skin more sensitive to sunlight. Inform your doctor if you have diabetes, high cholesterol, liver disease, kidney disease, or a history of pancreatitis. Regular blood tests to check liver function and lipid levels are essential. Do not stop or change the dose without consulting your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dry skin, dry eyes, and bone changes. They may also have reduced liver and kidney function, which can affect how the medicine is processed. Regular monitoring of liver function, lipid levels, and bone health is particularly important in this age group. The dose should be selected with caution and individualized by a qualified clinician.
🤰 Pregnancy Planning (TTC)
This medicine is strictly contraindicated in pregnancy and in women planning to become pregnant. Women of childbearing potential must use two reliable forms of contraception for at least one month before starting treatment, during treatment, and for three years after stopping. Pregnancy must be ruled out before starting and monthly during treatment. If you are planning a pregnancy, discuss with your doctor well in advance to plan an appropriate timeline for stopping the medicine.
🏥 Post-Surgery Considerations
This medicine can affect wound healing and increase the risk of bleeding. Inform your surgeon that you are taking this medicine before any surgery. Your doctor may advise you to stop the medicine temporarily before surgery. Do not stop the medicine without consulting your doctor.
🦷 Dental Procedures
This medicine can cause dry mouth and increase the risk of dental problems. Inform your dentist that you are taking this medicine before any dental procedure. Good oral hygiene and regular dental check-ups are recommended. If you need dental surgery, your doctor may advise you to stop the medicine temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause joint and muscle pain, which may affect your ability to exercise. If you experience bone or joint pain, avoid high-impact activities and consult your doctor. Regular low-impact exercise like walking or swimming is generally safe and beneficial. However, if you have bone changes from long-term use, your doctor may advise you to avoid activities that increase the risk of fractures.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dry eyes and decreased night vision, which can affect your ability to drive or operate machinery, especially at night. It can also cause fatigue and joint pain, which may impact your work performance. If your job involves driving or operating heavy machinery, discuss with your doctor whether it is safe for you to continue. Most people can continue their normal activities with some adjustments, such as using artificial tears and taking breaks if needed.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will decide when to stop based on your response to treatment and any side effects. If you experience serious side effects such as severe headache, vision changes, yellowing of skin or eyes, or severe abdominal pain, stop the medicine and seek immediate medical attention. If you become pregnant, stop the medicine immediately and contact your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to bone changes such as hyperostosis and reduced bone density, which may increase the risk of fractures. It can also cause persistent dry skin, dry eyes, and hair loss. Regular monitoring of liver function, lipid levels, and bone health is recommended. Some patients may experience decreased night vision. The medicine can remain in the body for a long time, so its effects may persist after stopping. Long-term use should be periodically reassessed by your doctor to ensure the benefits outweigh the risks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Creams and ointments containing corticosteroids, vitamin D analogues, or coal tar can be used for milder psoriasis.
Evidence: Well-establishedUltraviolet light therapy (UVB or PUVA) can be effective for moderate to severe psoriasis.
Evidence: Well-establishedAn oral immunosuppressant used for severe psoriasis, but with different side effects and monitoring requirements.
Evidence: Well-establishedInjectable medicines that target specific parts of the immune system, used for severe psoriasis.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine is not known to interact with vaccines. However, because it can affect the immune system, live vaccines should be avoided during treatment. Consult your doctor before receiving any vaccination while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container, tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a letter from your doctor explaining why you need this medicine, especially if you are traveling internationally. Keep the medicine in your carry-on luggage to avoid loss or temperature extremes. Store it at room temperature and protect it from light and moisture. If you are crossing time zones, continue taking your dose at the same time each day according to your home schedule, or consult your doctor for adjustments. Do not donate blood during travel or for three years after stopping this medicine.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts to show effects within 2 to 4 weeks, but full therapeutic benefit may take 2 to 3 months. It is important to be patient and continue as prescribed.
A: Yes, you should take this medicine with a meal, preferably one that contains some fat, to improve absorption.
A: Avoid alcohol completely, do not take vitamin A supplements, and do not donate blood. Also, avoid excessive sun exposure and use sunscreen.
A: Watch for severe headache, vision changes, yellowing of skin or eyes, severe abdominal pain, and signs of allergic reaction. Report these to your doctor immediately.
A: No, this medicine causes severe birth defects. Women must use two reliable forms of contraception and have monthly pregnancy tests. Pregnancy should be avoided during treatment and for three years after stopping.
🤔 Common Patient Concerns
🔄 Substitutes for acipsor 25mg capsule
View AllAlternative brands with exact same active ingredient:
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sentrane 25mg capsuleTaj Pharma India Ltd ₹386.25 41.9% CHEAPER
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glacitret 25mg capsuleTripada Biotec Pvt Ltd ₹464.06 30.2% CHEAPER
-
acitinext 25 capsuleEthinext Pharma ₹506.25 23.8% CHEAPER
-
psotretin 25mg tabletNuper therapeutics ₹515.63 22.4% CHEAPER
-
a tret 25mg capsuleKaizen Pharmaceuticals Pvt Ltd ₹553.13 16.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without regular blood tests.
Fact: Regular blood tests for liver function and lipid levels are essential because this medicine can cause serious liver and lipid abnormalities. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine is strictly contraindicated during pregnancy as it causes severe birth defects. - Myth: You can stop taking this medicine as soon as your skin clears.
Fact: You should only stop this medicine under your doctor's supervision, as stopping abruptly may cause a flare-up. - Myth: This medicine is a cure for psoriasis.
Fact: This medicine controls symptoms but does not cure psoriasis. Treatment is often long-term.
🔄 Alternative Options
Generic Alternatives
- Acitretin 25 mg capsule
Brand Alternatives
- Acrotac 25mg capsule