alfam 400mg tablet - Ibuprofen (400mg) medicine

Alfam 400mg Tablet: Complete Medicine Guide

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Ibuprofen (400mg)
🏭 Albert David Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 30, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. This medicine should be avoided in the third trimester of pregnancy because it may cause premature closure of the ductus arteriosus and other complications. Use in the first and second trimester only if clearly needed and advised by a doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for pain, fever, and inflammation.
Reviewed by
SaathiMed Expert Panel | Oct 30, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
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When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unexplained bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is alfam 400mg tablet used for?

This medicine contains Ibuprofen 400 mg, an NSAID used to relieve mild to moderate pain, reduce fever, and ease inflammation. It works by blocking COX enzymes and reducing prostaglandins. Take it with food, avoid alcohol, and do not exceed the recommended dose.

  • Generic Name: Ibuprofen
  • Manufacturer: Albert David Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alfam 400mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा इबुप्रोफेन 400 मिलीग्राम से बनी है और दर्द, सूजन और बुखार को कम करने के लिए इस्तेमाल की जाती है। यह सिरदर्द, दांत दर्द, मासिक धर्म के दर्द, मांसपेशियों के दर्द और जोड़ों के दर्द में राहत देती है। यह गठिया जैसी सूजन वाली बीमारियों में भी फायदेमंद है। इसे खाने के साथ लें ताकि पेट में जलन न हो। इस दवा को डॉक्टर की सलाह के बिना लंबे समय तक न लें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में पेट दर्द, जलन, मतली, उल्टी, चक्कर आना और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव कम होते हैं लेकिन पेट या आंतों में खून आना, किडनी की समस्या, लीवर की समस्या, हृदयाघात या लकवा जैसी गंभीर स्थितियां हो सकती हैं। अगर काला मल, खून की उल्टी, सांस लेने में तकलीफ, चेहरे या गले में सूजन, या पेशाब कम आना जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खाने के साथ लें ताकि पेट में जलन न हो। शराब न पिएं क्योंकि इससे पेट में खून आने का खतरा बढ़ जाता है। गर्भावस्था के तीसरे महीने में इस दवा का इस्तेमाल न करें। अगर आपको किडनी, लीवर, दिल की बीमारी, अस्थमा या पेट के अल्सर की समस्या है तो डॉक्टर को बताएं। दवा को ठंडी और सूखी जगह पर रखें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 alfam 400mg tablet Uses & Benefits

[{"condition":"Mild to moderate pain","description":"This medicine provides relief from headache, toothache, menstrual cramps, muscle aches, and back pain by reducing prostaglandin production.","evidence":"Well-established"},{"condition":"Fever","description":"This medicine lowers elevated body temperature by acting on the hypothalamus to reduce fever.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"This medicine reduces joint pain and stiffness and improves mobility in osteoarthritis of the knee, hip, and hand.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"This medicine helps control pain and inflammation" class="semantic-link" title="Medicines for swelling">swelling in rheumatoid arthritis as part of a comprehensive treatment plan.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"This medicine relieves menstrual cramps by reducing uterine prostaglandins.","evidence":"Well-established"},{"condition":"Soft tissue injuries","description":"This medicine reduces pain and swelling after sprains, strains, and sports injuries.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine attacks","description":"Sometimes used to relieve acute migraine headache, though not specifically approved for this use.","evidence":"Limited"},{"condition":"Altitudinal headache","description":"Occasionally used to prevent or treat headache at high altitude.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation

Also treats: Fever, Osteoarthritis, Rheumatoid arthritis, Dysmenorrhea, Soft tissue injuries

📋 Drug Information

Generic Name(s)Ibuprofen
Brand NameAdol 200mg Tablet
ManufacturerAlbert David Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C, away from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach upset.
2
Use the lowest effective dose for the shortest possible time.
3
Avoid alcohol while taking this medicine to prevent stomach bleeding.
4
Do not take other NSAIDs or pain relievers without consulting your doctor.
5
If you have kidney, liver, or heart disease, tell your doctor before using this medicine.
6
Report any unusual bleeding, bruising, or black stools immediately.
7
Do not use this medicine for more than 10 days for pain or 3 days for fever without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Headache
This medicine is commonly used for headache relief.
Likely Use
✅
Fever
This medicine helps reduce fever.
Likely Use
✅
Joint pain
This medicine is used for joint pain and inflammation.
Likely Use
❌
Chest pain
This medicine is not for chest pain. Seek emergency care.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed from the gastrointestinal tract after oral administration. Peak plasma levels are usually reached within 1 to 2 hours when taken on an empty stomach, but food can delay absorption without significantly reducing the total amount absorbed.
DistributionThis medicine is highly bound to plasma proteins and distributes into synovial fluid, which is important for its use in joint pain. It crosses the placenta and is excreted in breast milk in small amounts.
Protein BindingApproximately 99% bound to plasma albumin.
MetabolismThis medicine is extensively metabolized in the liver, mainly by the cytochrome P450 enzyme CYP2C9, into inactive metabolites.
Half-LifeThe elimination half-life is approximately 2 hours.
ExcretionThis medicine and its metabolites are excreted primarily in the urine, with a small amount excreted in bile and feces.
BioavailabilityThe oral bioavailability of this medicine is approximately 80% to 90%.
Onset of ActionPain relief usually begins within 30 to 60 minutes after taking this medicine on an empty stomach.
Peak Plasma TimePeak plasma concentration occurs about 1 to 2 hours after oral administration.
Duration of ActionThe analgesic and antipyretic effects of this medicine generally last 4 to 6 hours.

How It Works

This medicine works by reversibly inhibiting the cyclooxygenase enzymes COX-1 and COX-2. These enzymes convert arachidonic acid into prostaglandins and thromboxane. By blocking this conversion, the medicine reduces prostaglandins that sensitize pain nerve endings, cause blood vessel dilation and swelling, and raise body temperature. The result is relief from pain, inflammation, and fever. Because it also inhibits COX-1 in the stomach and platelets, it can cause stomach irritation and increased bleeding tendency.

Mechanism Steps

1
Absorption and distribution: After swallowing, this medicine is absorbed from the stomach and small intestine into the bloodstream and distributed to tissues.
2
COX enzyme binding: The medicine binds reversibly to both COX-1 and COX-2 enzymes inside cells.
3
Blockade of prostaglandin synthesis: By occupying the active site of COX enzymes, it prevents arachidonic acid from being converted into prostaglandin H2.
4
Reduced pain and fever mediators: Lower levels of prostaglandins reduce pain nerve sensitization and reset the hypothalamic temperature set point downward.
5
Reduced inflammation: Fewer prostaglandins and related compounds lead to less vasodilation, less swelling, and less recruitment of inflammatory cells.
6
Platelet and gastric effects: Blockade of COX-1 in platelets reduces thromboxane A2 production, mildly impairing clot formation, and in the stomach it reduces protective mucus.

💡 How to Take alfam 400mg tablet

Strength: Ibuprofen 400 mg immediate-release tablet

1Swallow the tablet whole with a full glass of water.
2Take this medicine with food or milk to reduce stomach upset.
3Do not crush, chew, or break the tablet.
4Take the lowest effective dose for the shortest possible time.
5Do not take more than the recommended dose or for longer than advised.
6If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 400 mg taken by mouth every 4 to 6 hours as needed for pain or fever. The maximum recommended daily dose is 1200 mg for over-the-counter use, but your doctor may prescribe up to 2400 mg per day for certain inflammatory conditions under close supervision. Take this medicine with food or milk to reduce stomach upset. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageOlder adults, especially those above 65 years, are at higher risk of stomach bleeding, kidney problems, and heart complications from this medicine. Use the lowest effective dose for the shortest possible time and consult a doctor regularly.
Renal ImpairmentThis medicine should be used with caution in people with kidney disease. If your kidney function is reduced, your doctor may recommend a lower dose or a different medicine. Do not use this medicine if you have severe kidney disease.
Hepatic ImpairmentThis medicine should be used with caution in people with liver disease. If your liver function is reduced, your doctor may recommend a lower dose or a different medicine. Do not use this medicine if you have severe liver disease.
Maximum Daily Dose1200 mg per day for over-the-counter use. Your doctor may prescribe up to 2400 mg per day for certain conditions under close supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.
Caffeine
Limit excessive intake
May increase stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alfam 400mg tablet

✅ Common Side Effects

Stomach pain or heartburn (Common (5-10%))
Take this medicine with food or milk. If pain persists, consult your doctor.
Nausea (Common (5-10%))
Take with a meal and stay hydrated. Consult your doctor if nausea continues.
Dizziness (Common (1-5%))
Avoid driving or operating machinery until you know how this medicine affects you.
Headache (Common (1-5%))
Usually resolves on its own. Consult your doctor if it persists.
Diarrhea or constipation (Common (1-5%))
Drink plenty of fluids. Consult your doctor if it does not settle.

🚨 Serious Side Effects

Gastrointestinal bleeding or ulcer (Rare (<0.1%))
Seek immediate medical attention if you notice black or tarry stools, vomiting blood, or severe stomach pain.
Kidney injury (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Liver injury (Rare (<0.1%))
Stop the medicine and seek medical help if you notice yellowing of the eyes or skin, dark urine, or severe abdominal pain.
Severe allergic reaction (Rare (<0.1%))
Seek emergency care if you develop swelling of the face, lips, or throat, difficulty breathing, or a severe rash.
Heart attack or stroke (Rare (<0.1%))
Call emergency services if you experience chest pain, shortness of breath, weakness on one side, or slurred speech.

⚠️ Rare Side Effects

Aseptic meningitis
Seek immediate medical attention if you develop severe headache, stiff neck, fever, and sensitivity to light.
Pancreatitis
Go to the emergency department if you have severe upper abdominal pain that radiates to your back.
Severe skin reactions such as Stevens-Johnson syndrome
Stop the medicine and seek emergency care if you develop a painful rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Aspirin Major
Other NSAIDs Major
Methotrexate Major
Lithium Major
ACE inhibitors Moderate
Diuretics Moderate
Corticosteroids Moderate
SSRIs Moderate
Fluconazole Moderate

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Other NSAIDs
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • ACE inhibitors and ARBs
  • Diuretics
  • Corticosteroids
  • Selective serotonin reuptake inhibitors (SSRIs)
  • CYP2C9 inhibitors such as fluconazole

🍷 Alcohol Interaction

Avoid drinking alcohol while taking this medicine. Alcohol increases the risk of stomach irritation, bleeding, and ulcers. It can also add to dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active stomach or intestinal ulcer or bleeding","Severe kidney disease","Severe liver disease","Severe heart failure","History of allergic reaction to ibuprofen, aspirin, or other NSAIDs","Third trimester of pregnancy","Use before or after coronary artery bypass graft surgery"]

⚠️ Warnings & Precautions

["Take this medicine with food or milk to reduce stomach upset.","Do not take more than the recommended dose or for longer than advised.","Avoid alcohol while taking this medicine.","Tell your doctor if you have kidney disease, liver disease, heart disease, high blood pressure, asthma, or a history of stomach ulcers.","Do not use this medicine during the third trimester of pregnancy.","Consult your doctor before using this medicine if you are breastfeeding.","This medicine may increase the risk of heart attack or stroke, especially with long-term use.","This medicine can cause dizziness; avoid driving or operating machinery until you know how it affects you.","Keep this medicine out of reach of children.","Store at room temperature away from moisture and direct sunlight."]

🤱 Lactation Safety

This medicine passes into breast milk in small amounts. It is generally considered compatible with breastfeeding for short-term use, but consult your doctor before using it while breastfeeding.

💊 Overdose Management

If you suspect an overdose of this medicine, seek emergency medical help immediately. Symptoms of overdose may include severe stomach pain, vomiting, drowsiness, ringing in the ears, blurred vision, confusion, and loss of consciousness. Treatment is supportive and may include activated charcoal, stomach lavage, and monitoring of vital signs and kidney function. Do not try to treat an overdose at home.

⏰ Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than advised. Take it with food or milk to reduce stomach upset. Swallow the tablet whole with a glass of water; do not crush or chew it. Avoid alcohol while taking this medicine because it increases the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. If you have kidney disease, liver disease, heart failure, high blood pressure, asthma, or a history of stomach ulcers, tell your doctor before using this medicine. Do not use this medicine during the third trimester of pregnancy. If you are breastfeeding, consult your doctor. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Older adults are at higher risk of stomach bleeding, kidney problems, and heart complications from this medicine. Use the lowest effective dose for the shortest possible time and consult a doctor regularly. Avoid long-term use unless specifically advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. This medicine may affect ovulation and is not recommended during the third trimester of pregnancy.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery. It may increase the risk of bleeding and interfere with healing. Your doctor may recommend a different pain reliever.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may increase the risk of bleeding during and after the procedure. Your dentist may advise you to stop it temporarily.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on your joints.
🥗
Regular low-impact exercise like swimming or walking can help manage pain.
😴
Practice good posture to prevent muscle strain.
💧
Include anti-inflammatory foods like fruits, vegetables, and omega-3 rich fish in your diet.
🧘
Get adequate sleep to help your body recover.
🌞
Manage stress through relaxation techniques like deep breathing or meditation.

🏋️ Exercise Considerations

This medicine may cause dizziness in some people. Avoid strenuous exercise or activities that require balance until you know how this medicine affects you. If you have joint pain, choose low-impact exercises and avoid high-impact activities that can worsen your condition.

🥗 Diet Recommendations

Include omega-3 rich foods like salmon, flaxseeds, and walnuts.
Reduce processed and fried food intake.
Stay well hydrated by drinking plenty of water.
Eat plenty of fruits and vegetables rich in antioxidants.
Limit caffeine and alcohol consumption.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It usually does not affect your ability to work, but if you feel unwell, take rest and consult your doctor.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your pain or fever does not improve within 10 days for pain or 3 days for fever, or if you experience side effects such as stomach pain, black stools, vomiting blood, rash, swelling, or decreased urine output. Do not stop long-term prescribed therapy without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of stomach ulcers, gastrointestinal bleeding, kidney problems, liver injury, high blood pressure, and heart attack or stroke. Regular monitoring of kidney function, liver function, blood pressure, and blood counts is recommended. Use the lowest effective dose for the shortest possible time.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve mobility.

Evidence: Well-established
Hot and cold compresses

Can help reduce localized pain and swelling.

Evidence: Limited
Acupuncture

May help with certain types of chronic pain.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before getting vaccinated.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture and direct sunlight. If you are traveling across time zones, continue taking your doses at the same intervals as prescribed. Check customs regulations for carrying medicines in your destination country. Keep enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 28-year-old woman with menstrual cramps
Used this medicine at the onset of cramps and found relief within an hour. She learned to take it with a light meal to avoid nausea.
💡 Lesson: Taking this medicine early in the pain cycle and with food provides better relief and fewer side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it on an empty stomach. Taking it with food may delay the onset slightly.

Q: Can I take this medicine on an empty stomach?

A: It is best to take this medicine with food or milk to reduce the risk of stomach upset and bleeding.

Q: How long can I take this medicine?

A: For over-the-counter use, do not take this medicine for more than 10 days for pain or 3 days for fever without consulting a doctor. Long-term use requires medical supervision.

Q: Is this medicine safe during pregnancy?

A: This medicine should be avoided in the third trimester. Use in early pregnancy only if clearly needed and advised by your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for alfam 400mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is completely safe for everyone.
    Fact: This medicine can cause stomach bleeding, kidney problems, and heart complications, especially with long-term use. It is not safe for everyone.
  • Myth: You can take this medicine on an empty stomach without any problem.
    Fact: Taking this medicine on an empty stomach increases the risk of stomach upset and bleeding. Always take it with food or milk.
  • Myth: This medicine can be taken for months without any monitoring.
    Fact: Long-term use requires regular monitoring of kidney function, liver function, blood pressure, and signs of bleeding.
  • Myth: This medicine is safe to take during pregnancy.
    Fact: This medicine should be avoided in the third trimester and used in early pregnancy only if clearly needed and advised by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Ibuprofen 400 mg tablet

Brand Alternatives

  • Alfam 400mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Ibuprofen 400 mg","class":"NSAID","main_use":"Pain, fever, inflammation","duration":"4-6 hours","common_side_effects":"Stomach upset, nausea, dizziness"},{"medicine":"Paracetamol 500 mg","class":"Analgesic and antipyretic","main_use":"Pain and fever","duration":"4-6 hours","common_side_effects":"Rare at recommended doses"},{"medicine":"Naproxen 250 mg","class":"NSAID","main_use":"Pain, fever, inflammation","duration":"8-12 hours","common_side_effects":"Stomach upset, heartburn, dizziness"}]

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