Alerfri SF 650 mg/60 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Irregular heartbeat or palpitations
If experiencing severe symptoms, call emergency services immediately.
What is alerfri sf 650 mg/60 mg/2.5 mg tablet used for?
This medicine is a combination of Paracetamol and Pseudoephedrine used to relieve nasal congestion, sinus pressure, headache, and fever associated with common cold, allergic rhinitis, or sinusitis. It works by reducing swelling in the nasal passages and relieving pain and fever.
- Generic Name: Paracetamol + Pseudoephedrine
- Manufacturer: Navil Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 alerfri sf 650 mg/60 mg/2.5 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल और स्यूडोएफेड्रिन का संयोजन है, जिसका उपयोग सर्दी, एलर्जी या साइनसाइटिस के कारण होने वाली नाक की भीड़, साइनस दबाव, सिरदर्द और बुखार से राहत के लिए किया जाता है। यह नाक के रक्त वाहिकाओं को सिकोड़कर भीड़ को कम करती है और दर्द तथा बुखार को कम करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में बेचैनी, अनिद्रा, चक्कर आना, सिरदर्द, मतली, उल्टी और मुँह सूखना शामिल हैं। स्यूडोएफेड्रिन के कारण हृदय गति बढ़ सकती है और रक्तचाप बढ़ सकता है। गंभीर दुष्प्रभावों में उच्च रक्तचाप संकट, अनियमित हृदय गति, दौरे और त्वचा पर गंभीर प्रतिक्रियाएँ शामिल हैं। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा की अनुशंसित खुराक से अधिक न लें। पैरासिटामोल युक्त अन्य दवाओं के साथ इसका सेवन न करें। बिना डॉक्टर की सलाह के 7 दिनों से अधिक इसका उपयोग न करें। शराब का सेवन न करें। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड विकार या प्रोस्टेट समस्या है तो डॉक्टर से परामर्श लें। चक्कर आने पर वाहन न चलाएँ। बच्चों की पहुँच से दूर रखें।
💊 alerfri sf 650 mg/60 mg/2.5 mg tablet Uses & Benefits
[{"condition":"Common cold with nasal congestion","description":"Relieves nasal stuffiness and sinus pressure while reducing associated pain and fever.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces nasal congestion and relieves headache or sinus pain.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps decrease mucosal inflammation" class="semantic-link" title="Medicines for swelling">swelling and alleviates facial pain and fever.","evidence":"Well-established"},{"condition":"Influenza","description":"Provides symptomatic relief of congestion, body ache, and fever.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Eustachian tube dysfunction","description":"Sometimes used to reduce congestion and improve ear pressure equalization.","evidence":"Limited"},{"condition":"Barotrauma prevention","description":"Occasionally used by divers or air travelers to reduce nasal congestion during pressure changes.","evidence":"Limited"}]
Primary treatment for: Common cold
Also treats: Allergic rhinitis, Sinusitis, Influenza
📋 Drug Information
| Generic Name(s) | Paracetamol + Pseudoephedrine |
| Brand Name | Actifed Plus Tablet |
| Manufacturer | Navil Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Analgesic, Antipyretic, Decongestant |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Paracetamol acts primarily in the central nervous system to reduce pain and fever, likely through inhibition of prostaglandin synthesis and modulation of pain pathways. Pseudoephedrine is a sympathomimetic amine that directly and indirectly stimulates alpha-adrenergic receptors, causing vasoconstriction of nasal mucosal blood vessels, which reduces swelling and congestion. The combination provides both decongestant and analgesic-antipyretic effects.
Mechanism Steps
💡 How to Take alerfri sf 650 mg/60 mg/2.5 mg tablet
Strength: Tablet containing Paracetamol 650 mg and Pseudoephedrine 60 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet every 6 to 8 hours as needed for symptoms, not to exceed 4 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the cardiovascular and central nervous system effects of pseudoephedrine. Use with caution and lower doses may be appropriate. Consult a doctor. |
| Renal Impairment | Pseudoephedrine is excreted renally; dose adjustment may be required in patients with renal impairment. Consult a doctor. |
| Hepatic Impairment | Paracetamol should be used with caution in patients with hepatic impairment. Dose reduction or avoidance may be necessary. Consult a doctor. |
| Maximum Daily Dose | Paracetamol: 4000 mg per day. Pseudoephedrine: 240 mg per day. Do not exceed these limits. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of alerfri sf 650 mg/60 mg/2.5 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Beta-blockers | Major | |
| Tricyclic antidepressants | Major | |
| Warfarin | Major | |
| Other sympathomimetics | Moderate | |
| Antihypertensives | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Beta-blockers
- Tricyclic antidepressants
- Warfarin
⚡ Moderate Interactions
- Other sympathomimetics
- Antihypertensives
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and may worsen the central nervous system effects of pseudoephedrine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to paracetamol or pseudoephedrine","Severe hypertension or severe coronary artery disease","Use within 14 days of MAOI therapy","Severe liver disease","Pheochromocytoma","Closed-angle glaucoma","Urinary retention"]
⚠️ Warnings & Precautions
["Do not exceed recommended dose.","Avoid alcohol.","Use with caution in patients with cardiovascular disease.","Use with caution in patients with diabetes, thyroid disorders, or prostate enlargement.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use for more than 7 days without consulting a doctor."]
🤱 Lactation Safety
Paracetamol is considered safe during breastfeeding. Pseudoephedrine passes into breast milk and may cause irritability or sleep disturbances in the infant. Consult your doctor before use.
💊 Overdose Management
Overdose of paracetamol can cause severe liver damage. Symptoms may include nausea, vomiting, abdominal pain, and yellowing of skin or eyes. Seek immediate medical attention. The antidote N-acetylcysteine should be administered as soon as possible. Pseudoephedrine overdose may cause tachycardia, hypertension, and CNS stimulation; supportive care is required.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Do not exceed the recommended dose of this medicine. Avoid taking other products containing paracetamol while on this medicine to prevent liver injury. Do not use this medicine for more than 7 days without consulting a doctor. Avoid alcohol consumption as it increases the risk of liver damage. If you have high blood pressure, heart disease, diabetes, thyroid disorder, or prostate enlargement, consult your doctor before use. Do not drive or operate heavy machinery if you feel dizzy. Keep out of reach of children. Store at room temperature away from moisture and heat. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the cardiovascular and central nervous system effects of pseudoephedrine. Use with caution and lower doses may be appropriate. Monitor blood pressure and heart rate regularly.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Paracetamol is generally considered safe, but pseudoephedrine should be used with caution.
🏥 Post-Surgery Considerations
Consult your surgeon before taking this medicine after surgery, as it may interact with other medications or affect blood pressure and heart rate.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with anesthetics or other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy or fatigued while taking this medicine. Listen to your body and rest if needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause insomnia if taken close to bedtime.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if symptoms persist beyond 7 days, if you experience severe side effects, or if you develop new symptoms. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of paracetamol can increase the risk of liver damage, especially with alcohol. Pseudoephedrine can cause cardiovascular effects. Use only as needed and consult a doctor if symptoms persist beyond 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help relieve nasal congestion without medication.
Evidence: Well-establishedHelps loosen mucus and relieve congestion.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule accordingly. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving symptoms within 30-60 minutes after taking it.
A: It is best taken with food to reduce stomach upset.
A: This medicine is not recommended for children under 12 years without doctor's advice.
🤔 Common Patient Concerns
🔄 Substitutes for alerfri sf 650 mg/60 mg/2.5 mg tablet
View AllAlternative brands with exact same active ingredient:
-
alcare-cc tabletHaledew Remedies ₹36.00 35.2% CHEAPER
-
sreyas tabletSKN Organics ₹53.63 3.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking more than the recommended dose can cause serious liver damage and cardiovascular effects. - Myth: This medicine is safe for everyone.
Fact: It is not safe for people with certain conditions like severe hypertension or those taking MAOIs.
🔄 Alternative Options
Generic Alternatives
- Paracetamol + Pseudoephedrine combination tablets