aldoloc 20 mg/50 mg tablet - Uses, Price, Side Effects & Substitutes
What is aldoloc 20 mg/50 mg tablet used for?
Aldostix 20 mg/50 mg tablet (Furosemide + Spironolactone) is used to treat CARDIAC. It contains Furosemide (20mg) + Spironolactone (50mg), which Furosemide inhibits Na-K-2Cl cotransporter in thick ascending limb of loop of He. Always consult your doctor before use. Take as prescribed.
- Generic Name: Furosemide + Spironolactone
- Manufacturer: Thrift Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ aldoloc 20 mg/50 mg tablet Uses & Benefits
Edema (CHF, hepatic cirrhosis, nephrotic syndrome), hypertension, primary hyperaldosteronism
Off-label uses: Polycystic ovary syndrome (spironolactone), heart failure (furosemide)
๐ Drug Information
| Generic Name(s) | Furosemide + Spironolactone |
| Brand Name | Aldostix 20 mg/50 mg tablet |
| Manufacturer | Thrift Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Diuretic, Potassium-sparing diuretic combination |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Furosemide inhibits Na-K-2Cl cotransporter in thick ascending limb of loop of Henle; Spironolactone competitively inhibits aldosterone in distal convoluted tubule, promoting Na and water excretion while retaining K
Mechanism Steps
๐ก How to Take aldoloc 20 mg/50 mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aldoloc 20 mg/50 mg tablet
โ Common Side Effects
- Hyperkalemia
- Hypokalemia (furosemide)
- Dehydration
- Dizziness
- Headache
- GI upset
- Gynecomastia (spironolactone)
๐จ Serious Side Effects
- Severe hyperkalemia
- Arrhythmias
- Acute renal failure
- Hepatic encephalopathy
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Pancreatitis
- Agranulocytosis
- Thrombocytopenia
- Anaphylaxis
- Hepatotoxicity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| ACE inhibitors | Major | Increased risk of hyperkalemia |
| Lithium | Major | Increased lithium toxicity |
| NSAIDs | Major | Reduced diuretic efficacy, increased nephrotoxicity |
| Digoxin | Major | Increased digoxin toxicity due to hypokalemia |
| Potassium supplements | Major | Severe hyperkalemia |
| Corticosteroids | Moderate | Increased hypokalemia risk |
| Antidiabetic agents | Moderate | Reduced hypoglycemic effect |
๐จ Major Interactions
- ACE inhibitors
- Angiotensin II receptor blockers
- Potassium supplements
- Potassium-sparing diuretics
- Lithium
- NSAIDs
- Digoxin
โก Moderate Interactions
- Corticosteroids
- Amphotericin B
- Antidiabetic agents
- Antihypertensives
- Cholestyramine
- Colestipol
โน๏ธ Minor Interactions
- Barbiturates
- Opioids
- Alcohol
๐ฝ๏ธ Food Interactions
High potassium foods, Licorice
๐ท Alcohol Interaction
May increase orthostatic hypotension risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Anuria, severe renal failure, hyperkalemia, Addison's disease, hypersensitivity to sulfonamides (furosemide), pregnancy (spironolactone)
๐ Monitoring Parameters
Serum electrolytes (K, Na, Mg, Ca), renal function, blood pressure, urine output, signs of dehydration
๐คฑ Lactation Safety
Furosemide excreted in milk; Spironolactone metabolite present; avoid or use with caution
๐ Overdose Management
Supportive care, monitor electrolytes, correct dehydration, treat hyperkalemia (IV calcium, insulin+glucose, kayexalate)
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close; do not double