aldactone plus 25mg/20mg tablet - Spironolactone (25mg) + Torasemide (20mg) medicine

aldactone plus 25mg/20mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ RPG Life Sciences Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is aldactone plus 25mg/20mg tablet used for?

Aldactone T 10 Tablet (Spironolactone + Torasemide) is used to treat CARDIAC. It contains Spironolactone (25mg) + Torasemide (20mg), which Spironolactone: Aldosterone receptor antagonist; Torasemide: Inhibits Na+/K+/2Cl. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Spironolactone + Torasemide
  • Manufacturer: RPG Life Sciences Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š aldactone plus 25mg/20mg tablet Uses & Benefits

Hypertension, congestive heart failure, edema, cirrhosis with ascites

Off-label uses: Hirsutism (spironolactone), acne (spironolactone)

๐Ÿ“‹ Drug Information

Generic Name(s)Spironolactone + Torasemide
Brand NameAldactone T 10 Tablet
ManufacturerRPG Life Sciences Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassPotassium-sparing diuretic + Loop diuretic
Route of AdministrationOral
StorageStore at 20-25ยฐC, protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSpironolactone: Well absorbed orally; Torasemide: Rapidly absorbed orally
DistributionSpironolactone: Extensive tissue distribution; Torasemide: Vd ~0.2 L/kg
Protein BindingSpironolactone: >90%; Torasemide: >99%
MetabolismSpironolactone: Hepatic to active metabolites (canrenone); Torasemide: Hepatic (CYP2C9)
Half-LifeSpironolactone: 1.4 hours (metabolites 16.5 hours); Torasemide: 3-4 hours
ExcretionSpironolactone: Urine and bile; Torasemide: Urine (80%) and feces (20%)
BioavailabilitySpironolactone: ~60-90%; Torasemide: ~80-90%
Onset of ActionSpironolactone: 2-3 days; Torasemide: 1 hour
Peak Plasma TimeSpironolactone: 2-4 hours; Torasemide: 1-2 hours
Duration of ActionSpironolactone: 2-3 days; Torasemide: 6-8 hours

How It Works

Spironolactone: Aldosterone receptor antagonist; Torasemide: Inhibits Na+/K+/2Cl- cotransporter in thick ascending limb of loop of Henle

Mechanism Steps

1Spironolactone binds to mineralocorticoid receptor, blocking aldosterone
2Reduces sodium reabsorption and potassium excretion in distal tubule
3Torasemide inhibits NKCC2 in thick ascending limb of loop of Henle

๐Ÿ’ก How to Take aldactone plus 25mg/20mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aldactone plus 25mg/20mg tablet

โœ… Common Side Effects

  • Hyperkalemia
  • Gynecomastia
  • Dizziness
  • Headache
  • Gastrointestinal upset

๐Ÿšจ Serious Side Effects

  • Severe hyperkalemia
  • Arrhythmias
  • Renal failure
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Agranulocytosis
  • Thrombocytopenia
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
ACE inhibitors Major Increased risk of hyperkalemia
Lithium Major Increased lithium toxicity
NSAIDs Moderate Reduced diuretic efficacy and increased nephrotoxicity
Warfarin Moderate Altered anticoagulant effect

๐Ÿšจ Major Interactions

  • ACE inhibitors
  • Angiotensin II receptor blockers
  • Potassium supplements
  • Lithium
  • Digoxin

โšก Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Cholestyramine
  • Warfarin

โ„น๏ธ Minor Interactions

  • Antidiabetic agents
  • Antihypertensives
  • Alcohol

๐Ÿฝ๏ธ Food Interactions

Avoid high-potassium foods; food may delay absorption

๐Ÿท Alcohol Interaction

May enhance hypotensive effect; avoid excessive alcohol

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Anuria, acute renal failure, hyperkalemia, Addison's disease, hypersensitivity

๐Ÿ“Š Monitoring Parameters

Serum potassium, renal function, blood pressure, electrolytes

๐Ÿคฑ Lactation Safety

Contraindicated (spironolactone metabolite excreted); torasemide caution

๐Ÿ’Š Overdose Management

Induce emesis/gastric lavage; monitor electrolytes; supportive care

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

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