Alcold Plus Tablet: Comprehensive Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Persistent fever for more than 3 days
- Rash or hives
If experiencing severe symptoms, call emergency services immediately.
What is alcold plus tablet used for?
This medicine is a combination of Loratadine (an antihistamine) and Paracetamol (a pain reliever and fever reducer). It is used to treat symptoms of allergies and the common cold, such as sneezing, runny nose, itchy eyes, headache, and fever. It works by blocking histamine and reducing pain and fever. It should be taken as prescribed by a doctor, usually every 6-8 hours as needed, without exceeding 4 tablets in 24 hours.
- Generic Name: Loratadine + Paracetamol
- Manufacturer: Legend Pharma Technologies
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 alcold plus tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लोराटाडीन और पैरासिटामोल का संयोजन है, जिसका उपयोग एलर्जी और सर्दी-जुकाम के लक्षणों जैसे छींक आना, नाक बहना, आंखों में खुजली, सिरदर्द और बुखार से राहत पाने के लिए किया जाता है। यह एलर्जी के कारण होने वाली प्रतिक्रियाओं को कम करने में मदद करती है और दर्द व बुखार को भी कम करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, थकान, मुंह सूखना, सिरदर्द और पेट में गड़बड़ी शामिल हो सकते हैं। गंभीर दुष्प्रभावों में एलर्जी, सांस लेने में कठिनाई, यकृत की क्षति और रक्त विकार शामिल हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। शराब का सेवन न करें क्योंकि इससे यकृत को नुकसान हो सकता है। निर्धारित खुराक से अधिक न लें। यदि लक्षण 7 दिनों से अधिक रहें तो डॉक्टर से परामर्श करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 alcold plus tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from fever, body ache, and allergic symptoms like sneezing and runny nose.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps reduce itching and hives due to allergic reactions.","evidence":"Well-established"},{"condition":"Mild to moderate pain","description":"Effective for headaches, muscle aches, and minor pains due to Paracetamol content.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever through the antipyretic action of Paracetamol.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Allergic conjunctivitis","description":"Sometimes used to relieve itchy, watery eyes due to allergies.","evidence":"Limited"},{"condition":"Sinusitis","description":"May help with allergic component of sinus congestion.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Common cold, Urticaria, Mild to moderate pain, Fever
📋 Drug Information
| Generic Name(s) | Loratadine + Paracetamol |
| Brand Name | Alcold Plus Tablet |
| Manufacturer | Legend Pharma Technologies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children and pets. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Loratadine is a second-generation antihistamine that selectively antagonizes peripheral histamine H1 receptors, reducing allergic symptoms such as sneezing, rhinorrhea, and itching. It has minimal central nervous system penetration, leading to less sedation compared to first-generation antihistamines. Paracetamol (acetaminophen) acts primarily in the central nervous system to produce analgesia and antipyresis. Its exact mechanism is not fully established, but it is believed to inhibit prostaglandin synthesis in the brain and may act on the hypothalamic heat-regulating center to reduce fever. The combination provides symptomatic relief for allergic and cold symptoms along with pain and fever reduction.
Mechanism Steps
💡 How to Take alcold plus tablet
Strength: Each tablet contains Loratadine 5 mg and Paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally every 6 to 8 hours as needed for symptoms, not to exceed 4 tablets in 24 hours. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and other medications. Do not self-medicate or exceed the recommended dose. For allergic rhinitis, one tablet once or twice daily may be sufficient. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially drowsiness and anticholinergic effects. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor for appropriate dosing. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine may need to be reduced or the dosing interval increased. Loratadine and Paracetamol are excreted by the kidneys. Consult a doctor for dose adjustment based on creatinine clearance. |
| Hepatic Impairment | In patients with hepatic impairment, the dose of Paracetamol should be reduced or avoided due to the risk of hepatotoxicity. Loratadine should be used with caution. Consult a doctor for appropriate dose adjustment. |
| Maximum Daily Dose | The maximum daily dose of Paracetamol should not exceed 4000 mg (8 tablets of 500 mg) in adults. The maximum daily dose of Loratadine should not exceed 10 mg (2 tablets of 5 mg). Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of alcold plus tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Ketoconazole | Major | |
| Erythromycin | Major | |
| Rifampicin | Moderate | |
| Carbamazepine | Moderate | |
| Benzodiazepines | Moderate | |
| Opioids | Moderate | |
| Metoclopramide | Moderate | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Alcohol
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
⚡ Moderate Interactions
- CNS depressants (e.g., benzodiazepines, opioids)
- Anticholinergic drugs (e.g., benztropine, tricyclic antidepressants)
- Metoclopramide
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Concurrent use can increase the risk of Paracetamol-induced liver damage and may enhance the sedative effects of Loratadine, leading to increased drowsiness and impaired motor skills. If you consume alcohol regularly, consult your doctor before taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Loratadine, Paracetamol, or any component of the formulation.","Severe hepatic impairment or active liver disease.","Severe renal impairment.","Children under 12 years of age (unless directed by a doctor).","Use with alcohol or other hepatotoxic drugs."]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose of Paracetamol; overdose can cause severe liver damage.","Avoid alcohol while taking this medicine.","Use with caution in patients with liver or kidney disease.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Consult a doctor if symptoms persist beyond 7 days or worsen.","Do not use for self-medication in children without medical advice.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children."]
🤱 Lactation Safety
Loratadine and Paracetamol are excreted in breast milk in small amounts. Loratadine is considered safe for use during breastfeeding, but Paracetamol should be used with caution. Consult your doctor before taking this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to Paracetamol. Symptoms of overdose may include nausea, vomiting, abdominal pain, confusion, and jaundice. If you suspect an overdose, seek immediate medical attention. The antidote for Paracetamol overdose is N-acetylcysteine, which is most effective when administered within 8-10 hours of ingestion. Loratadine overdose may cause drowsiness, tachycardia, and headache; treatment is supportive. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have liver or kidney disease, alcoholism, or any allergies. Do not exceed the recommended dose of Paracetamol, as it can cause serious liver damage. Avoid consuming alcohol while taking this medicine, as it increases the risk of liver toxicity and may enhance drowsiness. This medicine may interact with other medications, including blood thinners, anticonvulsants, and certain antibiotics. Do not use this medicine for more than 7 days for pain or 3 days for fever without consulting a doctor. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children. Store at room temperature away from moisture and heat. Do not use if the packaging is damaged or if the expiry date has passed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, particularly drowsiness, dry mouth, and dizziness. They may also have reduced liver and kidney function, requiring dose adjustments. Consult a doctor for appropriate dosing and monitoring.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Both Loratadine and Paracetamol are considered safe in pregnancy when used as directed, but the combination should be used only if clearly needed. Discuss the risks and benefits with your healthcare provider.
🏥 Post-Surgery Considerations
After surgery, consult your doctor before taking this medicine. Paracetamol may be used for pain relief, but Loratadine may interact with other medications. Follow your surgeon's instructions regarding medication use.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with anesthetics or other medications used during dental work. Your dentist may advise you to stop or adjust the dose temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. Light exercise like walking is generally safe if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to work at a desk job, but if you feel drowsy, take a break. Inform your employer if your work involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms persist beyond 7 days, if they worsen, or if you experience any serious side effects such as allergic reactions, yellowing of skin or eyes, or severe abdominal pain. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine, especially the Paracetamol component, can increase the risk of liver and kidney damage. Regular monitoring of liver and kidney function may be required if used for extended periods. It is not recommended for chronic use without medical supervision. Consult your doctor if you need to take this medicine for more than 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps clear nasal passages and reduce allergy symptoms.
Evidence: Well-establishedCan relieve nasal congestion and soothe irritated airways.
Evidence: LimitedReducing exposure to allergens can prevent symptoms.
Evidence: Well-establishedAllergy shots can provide long-term relief for allergic rhinitis.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before receiving any vaccination. It is safe to take this medicine before or after vaccination unless advised otherwise.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medications. Always keep it in your carry-on luggage. Do not leave it in a hot car.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Loratadine starts working within 1-3 hours, while Paracetamol starts within 30-60 minutes. You may feel relief from fever and pain within an hour, and allergy symptoms within a few hours.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Both Loratadine and Paracetamol are FDA Pregnancy Category B. However, consult your doctor before taking this medicine during pregnancy.
A: No, alcohol should be avoided as it increases the risk of liver damage and drowsiness.
🤔 Common Patient Concerns
🔄 Substitutes for alcold plus tablet
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure allergies permanently.
Fact: This medicine provides symptomatic relief but does not cure allergies. It reduces symptoms while you are taking it. - Myth: It is safe to take this medicine with alcohol.
Fact: Alcohol should be avoided as it increases the risk of liver damage and drowsiness. - Myth: You can take this medicine for as long as you want.
Fact: Prolonged use without medical supervision can be harmful, especially to the liver. Consult a doctor if symptoms persist beyond 7 days. - Myth: This medicine is safe for children without a doctor's advice.
Fact: Pediatric dosing is not established; consult a pediatrician before giving this medicine to children.
🔄 Alternative Options
Generic Alternatives
- Loratadine + Paracetamol combination tablets from other manufacturers
Brand Alternatives
- Alcold Plus Tablet