alcold plus tablet - Loratadine (5mg) + Paracetamol (500mg) medicine

Alcold Plus Tablet - Uses, Price, Side Effects

4.7 (13 reviews)
๐Ÿญ Legend Pharma Technologies ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is alcold plus tablet used for?

Alcold Plus Tablet combines Loratadine (5mg) and Paracetamol (500mg) to relieve allergy symptoms like sneezing, runny nose, and itchy eyes, while also reducing fever and mild pain. It works by blocking histamine and inhibiting prostaglandin synthesis.

  • Generic Name: Loratadine + Paracetamol
  • Manufacturer: Legend Pharma Technologies
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š alcold plus tablet Uses & Benefits

Allergic rhinitis, common cold symptoms, fever, headache, mild pain

Off-label uses: Urticaria, pruritus, motion sickness (loratadine)

๐Ÿ“‹ Drug Information

Generic Name(s)Loratadine + Paracetamol
Brand NameAlcold Plus Tablet
ManufacturerLegend Pharma Technologies
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract
DistributionWidely distributed throughout body tissues
Protein BindingLoratadine: 97-99%; Paracetamol: 10-25%
MetabolismLoratadine: Hepatic via CYP3A4 and CYP2D6; Paracetamol: Hepatic via conjugation
Half-LifeLoratadine: 8-14 hours; Paracetamol: 1.5-3 hours
ExcretionLoratadine: Urine (40%) and feces (40%); Paracetamol: Urine (90-100%)
BioavailabilityLoratadine: ~40%; Paracetamol: 60-98%
Onset of ActionLoratadine: 1-3 hours; Paracetamol: 30-60 minutes
Peak Plasma TimeLoratadine: 1-2 hours; Paracetamol: 30-60 minutes
Duration of ActionLoratadine: 24 hours; Paracetamol: 4-6 hours

How It Works

Loratadine: Selective peripheral H1 receptor antagonist; Paracetamol: COX inhibition in CNS, analgesic and antipyretic

Mechanism Steps

1Loratadine binds to peripheral H1 receptors, blocking histamine action
2Reduces allergic symptoms like sneezing, itching, rhinorrhea
3Paracetamol inhibits COX-2 in the CNS, reducing prostaglandin synthesis

๐Ÿ’ก How to Take alcold plus tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of alcold plus tablet

โœ… Common Side Effects

  • Drowsiness
  • Fatigue
  • Dry mouth
  • Headache
  • Nausea

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Anaphylaxis
  • Blood dyscrasias

โš ๏ธ Rare Side Effects

  • Tachycardia
  • Palpitations
  • Seizures
  • Hallucinations

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Alcohol Moderate Increased liver toxicity
MAOIs Moderate Increased risk of hypertensive crisis

๐Ÿšจ Major Interactions

  • MAOIs
  • Alcohol
  • CNS depressants
  • Warfarin
  • Isoniazid
  • Rifampin

โšก Moderate Interactions

  • Ketoconazole
  • Erythromycin
  • Cimetidine
  • Amiodarone
  • Fluconazole

โ„น๏ธ Minor Interactions

  • Antacids
  • Caffeine
  • Theophylline

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase loratadine levels; food may delay absorption

๐Ÿท Alcohol Interaction

Increased risk of hepatotoxicity with paracetamol; additive CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to components, severe hepatic impairment, acute liver disease

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, CBC

๐Ÿคฑ Lactation Safety

Loratadine: Excreted in milk, use with caution; Paracetamol: Safe

๐Ÿ’Š Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory