Loratadine + Pseudoephedrine Tablet: Complete Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Chest pain or palpitations
- Severe headache with blurred vision
- Difficulty urinating
- Swelling of face, lips, or throat
- Severe dizziness or fainting
- Rapid or irregular heartbeat
- Shortness of breath
If experiencing severe symptoms, call emergency services immediately.
What is claridin d 5 mg/120 mg tablet used for?
This medicine is a combination of Loratadine (antihistamine) and Pseudoephedrine (decongestant) used to treat nasal congestion, sneezing, and runny nose due to allergies or colds. It works by blocking histamine and constricting nasal blood vessels. It is for short-term use in adults and children over 12 years.
- Generic Name: Loratadine + Pseudoephedrine
- Manufacturer: Morepen Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 claridin d 5 mg/120 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एलर्जी और सर्दी-जुकाम से होने वाली नाक की भीड़, छींक, बहती नाक और आंखों में खुजली को कम करने के लिए इस्तेमाल की जाती है। इसमें लोराटाडीन और स्यूडोएफेड्रिन होते हैं। यह 12 साल से बड़े बच्चों और वयस्कों के लिए है। इसे डॉक्टर की सलाह के बिना 7 दिन से ज्यादा न लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुंह सूखना, सिरदर्द, नींद आना, बेचैनी, अनिद्रा और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन धड़कन तेज होना, रक्तचाप बढ़ना, पेशाब में रुकावट या एलर्जी प्रतिक्रिया हो सकती है। ऐसा होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुद से मात्रा न बढ़ाएं। गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब न पिएं। अगर आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा या प्रोस्टेट की समस्या है तो डॉक्टर को बताएं। 7 दिन से ज्यादा इस्तेमाल न करें।
💊 claridin d 5 mg/120 mg tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief of nasal congestion and sneezing due to viral upper respiratory tract infections.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps reduce nasal congestion and pressure in acute or chronic sinusitis.","evidence":"Moderate"},{"condition":"Eustachian tube dysfunction","description":"May help relieve congestion and pressure in the middle ear related to allergies or colds.","evidence":"Limited"}]
Off-label uses: [{"condition":"Allergic conjunctivitis","description":"Sometimes used off-label to relieve itchy, watery eyes due to allergies.","evidence":"Limited"},{"condition":"Urticaria","description":"Loratadine component may help with itching and hives, but pseudoephedrine is not typically indicated.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Common cold, Sinusitis, Eustachian tube dysfunction
📋 Drug Information
| Generic Name(s) | Loratadine + Pseudoephedrine |
| Brand Name | Claridin D |
| Manufacturer | Morepen Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Decongestant |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. |
| Shelf Life | 24 months from date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Loratadine is a selective peripheral H1-receptor antagonist. It inhibits the effects of histamine, a substance released by mast cells during allergic reactions, thereby reducing sneezing, runny nose, and itching. Pseudoephedrine is a sympathomimetic amine that directly and indirectly stimulates alpha-adrenergic receptors, causing vasoconstriction in the nasal mucosa. This reduces swelling and congestion in the nasal passages.
Mechanism Steps
💡 How to Take claridin d 5 mg/120 mg tablet
Strength: Tablet containing Loratadine 5 mg and Pseudoephedrine 120 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Loratadine 5 mg + Pseudoephedrine 120 mg) taken orally every 12 hours, not to exceed two tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use for more than 7 days without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of pseudoephedrine and loratadine. Use with caution and lower doses may be considered. Consult a doctor. |
| Renal Impairment | Use with caution in renal impairment. Dose adjustment may be needed. Consult a doctor. |
| Hepatic Impairment | Use with caution in hepatic impairment. Dose adjustment may be needed. Consult a doctor. |
| Maximum Daily Dose | Two tablets (Loratadine 10 mg + Pseudoephedrine 240 mg) in 24 hours. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of claridin d 5 mg/120 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Beta-blockers | Major | |
| Tricyclic antidepressants | Major | |
| Ketoconazole | Moderate | |
| Erythromycin | Moderate | |
| Fluoxetine | Moderate | |
| Antihypertensives | Moderate | |
| Alcohol | Minor | |
| CNS depressants | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Beta-blockers
- Tricyclic antidepressants
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
- Antihypertensives
🍷 Alcohol Interaction
Alcohol may increase drowsiness and impair motor skills. Avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe hypertension or coronary artery disease","Hyperthyroidism","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Concurrent use with MAOIs or within 14 days of stopping MAOIs","Known hypersensitivity to loratadine or pseudoephedrine"]
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disease, diabetes, or thyroid disorders.","May cause drowsiness; avoid driving or operating machinery until effects are known.","Do not exceed recommended dose or duration of use.","Avoid alcohol and other CNS depressants.","Consult a doctor if symptoms persist beyond 7 days or worsen."]
🤱 Lactation Safety
Loratadine and pseudoephedrine are excreted in breast milk. Consult a doctor before use during breastfeeding. Pseudoephedrine may reduce milk supply.
💊 Overdose Management
Overdose may cause drowsiness, tachycardia, hypertension, or seizures. Seek immediate medical attention. Treatment is symptomatic and supportive. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and cardiac rhythm.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid alcohol and other central nervous system depressants while taking this medicine. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or prostate enlargement. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of pseudoephedrine, including increased blood pressure, palpitations, and urinary retention. Use with caution and lower doses may be needed. Consult a doctor.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are pregnant, planning pregnancy, or breastfeeding. Pseudoephedrine may not be safe during pregnancy.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, especially if you have cardiovascular or urinary conditions. It may interact with anesthetics or other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with local anesthetics or other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, affecting your ability to drive or operate machinery. It may also cause nervousness or insomnia, impacting work performance. Adjust dosing times to minimize interference with daily activities.
🛑 When to Stop This Medicine
Stop this medicine if symptoms persist beyond 7 days, worsen, or if you experience serious side effects such as palpitations, severe headache, or difficulty urinating. Consult your doctor before stopping if you have been on it for an extended period.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of pseudoephedrine may lead to rebound congestion, increased blood pressure, and cardiac effects. Loratadine is generally safe for long-term use but should be used under medical supervision. Regular monitoring of blood pressure and heart rate is advised if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps clear nasal passages and reduce congestion without medication.
Evidence: Well-establishedTarget allergic symptoms locally with fewer systemic effects.
Evidence: Well-establishedReducing exposure to allergens can prevent symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are acutely ill with fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying medications. Do not leave in hot cars or checked luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 1 to 3 hours after taking a dose.
A: It may cause insomnia in some people. If it affects your sleep, take the last dose before evening.
A: It is not recommended for children under 12 years without medical advice.
A: Do not take with other decongestants or antihistamines without consulting a doctor.
🤔 Common Patient Concerns
🔄 Substitutes for claridin d 5 mg/120 mg tablet
View AllAlternative brands with exact same active ingredient:
-
lorfast d 5mg/120mg tabletCadila Pharmaceuticals Ltd ₹10.95 7.7% CHEAPER
-
loridin d tabletZydus Cadila ₹16.21 36.7% COSTLIER
-
loran d tabletAnglo-French Drugs & Industries Ltd ₹37.50 216.2% COSTLIER
-
lormeg d 5mg/120mg tabletAlembic Pharmaceuticals Ltd ₹49.00 313.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure allergies permanently.
Fact: This medicine only relieves symptoms; it does not cure allergies. - Myth: It is safe to take this medicine for weeks without a break.
Fact: It should not be used for more than 7 days without medical advice. - Myth: This medicine is safe for everyone.
Fact: It is not safe for people with certain heart conditions, high blood pressure, or glaucoma.
🔄 Alternative Options
Generic Alternatives
- Loratadine + Pseudoephedrine generic tablets