alcicold-plus tablet - Ambroxol (60mg) + Levocetirizine (2.5mg) medicine

alcicold-plus tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Alicia Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is alcicold-plus tablet used for?

Alerfix Total Tablet SR (Ambroxol + Levocetirizine) is used to treat RESPIRATORY. It contains Ambroxol (60mg) + Levocetirizine (2.5mg), which Ambroxol increases mucus clearance by stimulating surfactant production and redu. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ambroxol + Levocetirizine
  • Manufacturer: Alicia Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š alcicold-plus tablet Uses & Benefits

Allergic rhinitis, urticaria, productive cough with mucus hypersecretion

Off-label uses: Chronic obstructive pulmonary disease (COPD) with mucus hypersecretion

๐Ÿ“‹ Drug Information

Generic Name(s)Ambroxol + Levocetirizine
Brand NameAlerfix Total Tablet SR
ManufacturerAlicia Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Antihistamine
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in body tissues
Protein BindingAmbroxol: ~90%; Levocetirizine: ~91%
MetabolismAmbroxol: Hepatic (glucuronidation); Levocetirizine: Minimal hepatic metabolism
Half-LifeAmbroxol: 7-12 hours; Levocetirizine: 6-10 hours
ExcretionAmbroxol: Renal (90%); Levocetirizine: Renal (85%)
BioavailabilityAmbroxol: ~70%; Levocetirizine: ~100%
Onset of ActionAmbroxol: 30 minutes; Levocetirizine: 1 hour
Peak Plasma TimeAmbroxol: 1-2 hours; Levocetirizine: 0.9 hours
Duration of ActionAmbroxol: 6-12 hours; Levocetirizine: 24 hours

How It Works

Ambroxol increases mucus clearance by stimulating surfactant production and reducing mucus viscosity; Levocetirizine selectively inhibits peripheral H1 receptors, reducing histamine-mediated allergic responses.

Mechanism Steps

1Ambroxol stimulates surfactant production in type II pneumocytes, reducing mucus viscosity.
2Ambroxol increases ciliary beat frequency, enhancing mucociliary clearance.
3Levocetirizine selectively blocks peripheral H1 receptors, preventing histamine binding.

๐Ÿ’ก How to Take alcicold-plus tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of alcicold-plus tablet

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Fatigue
  • Headache
  • Nausea

๐Ÿšจ Serious Side Effects

  • Severe allergic reactions
  • Hepatotoxicity
  • Seizures

โš ๏ธ Rare Side Effects

  • Palpitations
  • Urinary retention
  • Blurred vision

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
CNS depressants Major Increased sedation and CNS depression
MAO inhibitors Major Increased anticholinergic and CNS effects
Anticholinergics Moderate Additive anticholinergic effects
Other antihistamines Moderate Increased antihistamine side effects
Cimetidine Minor Possible increased levocetirizine levels
Ritonavir Minor Possible increased levocetirizine levels

๐Ÿšจ Major Interactions

  • CNS depressants
  • MAO inhibitors

โšก Moderate Interactions

  • Anticholinergics
  • Other antihistamines

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Ritonavir

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

May increase CNS depression; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe renal impairment (CrCl <10 mL/min), pregnancy (first trimester for ambroxol)

๐Ÿ“Š Monitoring Parameters

Renal function, CNS effects, allergic symptoms

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; gastric lavage if recent ingestion; monitor for CNS depression and anticholinergic effects

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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