agradine 5% ointment - Povidone Iodine (5% w/w) medicine

agradine 5% ointment

4.8 (10 reviews)
๐Ÿญ Agrawal Drugs Pvt. Ltd. ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is agradine 5% ointment used for?

Apidine Eye Drop (Povidone Iodine) is used to treat OPHTHAL OTOLOGICALS. It contains Povidone Iodine (5% w/w), which Oxidizes microbial proteins and DNA, leading to cell death.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Povidone Iodine
  • Manufacturer: Agrawal Drugs Pvt. Ltd.
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š agradine 5% ointment Uses & Benefits

Preoperative antisepsis in ophthalmic surgery; treatment of conjunctivitis and keratitis.

Off-label uses: Viral conjunctivitis, Fungal keratitis

๐Ÿ“‹ Drug Information

Generic Name(s)Povidone Iodine
Brand NameApidine Eye Drop
ManufacturerAgrawal Drugs Pvt. Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL OTOLOGICALS
Action ClassAntiseptics and disinfectants
Route of AdministrationTopical ophthalmic
StorageStore at 15-30ยฐC; protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption when applied topically to the eye.
DistributionLimited to ocular tissues; negligible systemic distribution.
Protein BindingNot applicable due to minimal systemic absorption.
MetabolismNot metabolized; iodine is released and may be reduced to iodide.
Half-LifeNot applicable; local action with rapid clearance from ocular surface.
ExcretionExcreted primarily in urine as iodide if absorbed systemically.
BioavailabilityNot applicable; topical administration with minimal systemic absorption.
Onset of ActionImmediate antimicrobial effect upon application.
Peak Plasma TimeNot applicable; minimal systemic absorption.
Duration of ActionUp to 24 hours after single application.

How It Works

Oxidizes microbial proteins and DNA, leading to cell death.

Mechanism Steps

1Povidone-iodine complex releases free iodine upon contact with ocular surface.
2Free iodine penetrates microbial cell walls.
3Iodine oxidizes proteins, nucleotides, and fatty acids.

๐Ÿ’ก How to Take agradine 5% ointment

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of agradine 5% ointment

โœ… Common Side Effects

  • Stinging
  • Burning
  • Temporary blurred vision

๐Ÿšจ Serious Side Effects

  • Allergic reaction
  • Thyroid dysfunction with prolonged use

โš ๏ธ Rare Side Effects

  • Corneal edema
  • Iritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Lithium Major Increased risk of hypothyroidism
Radioactive iodine therapy Major Reduced uptake of radioactive iodine
Antithyroid drugs Moderate Additive antithyroid effect
Potassium iodide Moderate Increased iodine levels
Topical corticosteroids Minor Possible reduced antimicrobial efficacy

๐Ÿšจ Major Interactions

  • Lithium
  • Radioactive iodine therapy

โšก Moderate Interactions

  • Antithyroid drugs
  • Potassium iodide

โ„น๏ธ Minor Interactions

  • Topical corticosteroids

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to iodine or any component; thyroid disorders (e.g., Hashimoto's thyroiditis).

๐Ÿ“Š Monitoring Parameters

Monitor for signs of irritation or allergic reaction.

๐Ÿคฑ Lactation Safety

Use with caution; limited data.

๐Ÿ’Š Overdose Management

Rinse eye with water; symptomatic treatment.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for agradine 5% ointment

View All

Alternative brands with exact same active ingredient (Povidone Iodine (5% w/w)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory