ampitrust 750 tablet - Sultamicillin tosilate (750mg) medicine

ampitrust 750 tablet

4.7 (19 reviews)
๐Ÿญ Fusion Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is ampitrust 750 tablet used for?

Ampisure Tablet (Sultamicillin tosilate) is used to treat ANTI INFECTIVES. It contains Sultamicillin tosilate (750mg), which Sultamicillin is a prodrug that releases ampicillin (a bactericidal beta-lactam . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Sultamicillin tosilate
  • Manufacturer: Fusion Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š ampitrust 750 tablet Uses & Benefits

Upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, septicemia.

Off-label uses: Prophylaxis in surgery, Lyme disease (early localized).

๐Ÿ“‹ Drug Information

Generic Name(s)Sultamicillin tosilate
Brand NameAmpisure Tablet
ManufacturerFusion Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAmpicillin & Sulbactam ester compound
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; prodrug hydrolyzed to ampicillin and sulbactam.
DistributionWidely distributed to tissues and body fluids including lungs, sinuses, middle ear, and bile.
Protein BindingAmpicillin: 15-25%; Sulbactam: ~38%
MetabolismSultamicillin is hydrolyzed by esterases in the gut wall and liver to ampicillin and sulbactam.
Half-LifeAmpicillin: ~1 hour; Sulbactam: ~1 hour
ExcretionPrimarily renal (glomerular filtration and tubular secretion); both components excreted unchanged in urine.
Bioavailability~80% (as ampicillin equivalents)
Onset of Action1-2 hours
Peak Plasma Time1-2 hours
Duration of Action6-8 hours

How It Works

Sultamicillin is a prodrug that releases ampicillin (a bactericidal beta-lactam antibiotic) and sulbactam (a beta-lactamase inhibitor). Ampicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), while sulbactam irreversibly inhibits beta-lactamases, protecting ampicillin from degradation.

Mechanism Steps

1Sultamicillin is absorbed and hydrolyzed by esterases to ampicillin and sulbactam.
2Ampicillin binds to penicillin-binding proteins (PBPs) on bacterial cell wall.
3Inhibition of transpeptidase and autolysin enzymes disrupts cell wall synthesis.

๐Ÿ’ก How to Take ampitrust 750 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of ampitrust 750 tablet

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Skin rash
  • Urticaria

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Clostridium difficile colitis
  • Seizures

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Agranulocytosis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Methotrexate Major Increased methotrexate toxicity
Warfarin Major Increased INR and bleeding risk
Oral contraceptives Major Reduced contraceptive efficacy
Allopurinol Moderate Increased risk of skin rash
Probenecid Moderate Decreased renal excretion of ampicillin and sulbactam
Aminoglycosides Moderate Physical incompatibility; avoid mixing
Chloramphenicol Minor Antagonistic effect
Tetracyclines Minor Antagonistic effect

๐Ÿšจ Major Interactions

  • Methotrexate
  • Warfarin
  • Oral contraceptives

โšก Moderate Interactions

  • Allopurinol
  • Probenecid
  • Aminoglycosides

โ„น๏ธ Minor Interactions

  • Chloramphenicol
  • Tetracyclines

๐Ÿฝ๏ธ Food Interactions

Food may reduce absorption; take on empty stomach.

๐Ÿท Alcohol Interaction

No direct interaction; avoid excessive alcohol due to general health.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to penicillins, cephalosporins, or any component; infectious mononucleosis (risk of maculopapular rash).

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, CBC, signs of hypersensitivity.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in low levels; use with caution.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may help remove drug.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for ampitrust 750 tablet

View All

Alternative brands with exact same active ingredient (Sultamicillin tosilate (750mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory