Acupenem 1000mg Injection: A Comprehensive Guide to Meropenem
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Seizures or sudden confusion
- Severe or persistent diarrhea
- Rash with blistering or peeling skin
- Decreased urine output or swelling in the legs
- Yellowing of the skin or eyes
- Unusual bleeding or bruising
- High fever with chills
If experiencing severe symptoms, call emergency services immediately.
What is admero 1gm injection used for?
This medicine is a broad-spectrum intravenous antibiotic containing meropenem, used to treat serious bacterial infections such as meningitis, pneumonia, and complicated abdominal infections. It works by killing bacteria and is reserved for resistant or severe infections.
- Generic Name: Meropenem
- Manufacturer: Adjener Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 admero 1gm injection के बारे में (Hindi Summary)
उपयोग: यह दवा मेरोपेनम नामक एंटीबायोटिक है, जिसे गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए नस के माध्यम से दिया जाता है। यह मेनिनजाइटिस, निमोनिया, पेट के गंभीर संक्रमण, मूत्र मार्ग के संक्रमण, त्वचा के संक्रमण और बुखार के साथ कम सफेद रक्त कोशिकाओं वाले मरीजों में उपयोग की जाती है। यह दवा बैक्टीरिया की कोशिका भित्ति को नष्ट करके उन्हें मार देती है। यह केवल अस्पताल में डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। इसका उपयोग वायरल संक्रमण जैसे सर्दी-जुकाम के लिए नहीं किया जाता।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, सिरदर्द, चकत्ते और इंजेक्शन लगाने की जगह पर दर्द या सूजन शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, दौरे, गंभीर दस्त, त्वचा पर गंभीर प्रतिक्रियाएं और रक्त विकार हो सकते हैं। यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, गंभीर दस्त, या त्वचा पर छाले दिखाई दें, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल में योग्य डॉक्टर द्वारा ही दी जानी चाहिए। इससे पहले कि आपको यह दवा दी जाए, अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों, विशेषकर गुर्दे की बीमारी, यकृत की बीमारी, दौरे की समस्या, और किसी भी एंटीबायोटिक से एलर्जी के बारे में बताएं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में भी बताएं। गर्भावस्था या स्तनपान के दौरान इस दवा का उपयोग करने से पहले डॉक्टर से सलाह लें। इलाज के दौरान अपने गुर्दे और यकृत की कार्यप्रणाली की निगरानी करवाएं। बेहतर महसूस होने पर भी दवा का कोर्स पूरा करें।
💊 admero 1gm injection Uses & Benefits
[{"condition":"Complicated intra-abdominal infections","description":"Used to treat serious infections within the abdomen, such as peritonitis and abscesses, often caused by multiple types of bacteria.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"Effective against meningitis caused by susceptible bacteria, including in pediatric patients, due to its ability to penetrate the cerebrospinal fluid.","evidence":"Well-established"},{"condition":"Community-acquired pneumonia","description":"Used for severe cases of pneumonia acquired outside of hospitals, especially when resistant organisms are suspected.","evidence":"Well-established"},{"condition":"Hospital-acquired pneumonia","description":"Treats pneumonia that develops during a hospital stay, including ventilator-associated pneumonia, often caused by multidrug-resistant bacteria.","evidence":"Well-established"},{"condition":"Complicated urinary tract infections","description":"Used for severe kidney and urinary tract infections, including pyelonephritis, that require intravenous therapy.","evidence":"Well-established"},{"condition":"Complicated skin and soft tissue infections","description":"Treats severe skin infections such as necrotizing fasciitis and diabetic foot infections.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"Used as empiric therapy in cancer patients with fever and low white blood cell counts, to cover a broad range of potential pathogens.","evidence":"Well-established"},{"condition":"Intrauterine infections","description":"Used to treat infections of the uterus and surrounding tissues, such as endometritis and pelvic inflammatory disease.","evidence":"Well-established"},{"condition":"Polymicrobial infections","description":"Effective against infections caused by multiple types of bacteria, including aerobic and anaerobic organisms.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Cystic fibrosis exacerbations","description":"Sometimes used to treat lung infections in cystic fibrosis patients when other antibiotics are not effective.","evidence":"Limited"},{"condition":"Nocardiosis","description":"May be used as an alternative treatment for infections caused by Nocardia species.","evidence":"Limited"},{"condition":"Melioidosis","description":"Used in some regions for the treatment of melioidosis, caused by Burkholderia pseudomallei.","evidence":"Limited"}]
Primary treatment for: Serious bacterial infections
Also treats: Complicated intra-abdominal infections, Bacterial meningitis, Community-acquired pneumonia, Hospital-acquired pneumonia, Complicated urinary tract infections, Complicated skin and soft tissue infections, Febrile neutropenia, Intrauterine infections, Polymicrobial infections
📋 Drug Information
| Generic Name(s) | Meropenem |
| Brand Name | Acupenem 1000mg Injection |
| Manufacturer | Adjener Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cell wall active agent -Carbapenems |
| Route of Administration | Intravenous (IV) infusion over 15 to 30 minutes, or as directed by a healthcare professional |
| Storage | Store the unreconstituted vial at room temperature between 20°C and 25°C (68°F to 77°F). Once reconstituted, the solution should be used immediately or stored as per the manufacturer's instructions. Do not freeze. |
| Shelf Life | The shelf life of the unreconstituted product is typically 24 to 36 months from the date of manufacture. Refer to the product packaging for the exact expiry date. |
| WHO Guideline | The World Health Organization includes meropenem in its Model List of Essential Medicines for the treatment of serious bacterial infections. It is recommended for use in hospitals where resistant bacteria are prevalent. |
| ICMR Guideline | The Indian Council of Medical Research recommends meropenem for the treatment of serious infections caused by multidrug-resistant organisms, based on culture and sensitivity reports. It should be used judiciously to prevent further resistance. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine exerts its bactericidal effect by inhibiting the synthesis of the bacterial cell wall. It binds to penicillin-binding proteins, which are enzymes involved in cross-linking the peptidoglycan layers of the cell wall. This binding prevents the formation of a stable cell wall, leading to bacterial cell lysis and death. It is stable against many beta-lactamases, including extended-spectrum beta-lactamases, which makes it effective against many resistant bacteria.
Mechanism Steps
💡 How to Take admero 1gm injection
Strength: This medicine is available as a sterile powder for injection in a 1000 mg (1 gram) strength. It is reconstituted with a suitable diluent before intravenous administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 500 mg to 1 gram administered intravenously every 8 hours, depending on the type and severity of the infection. For meningitis, the recommended dose is 2 grams every 8 hours. For complicated intra-abdominal infections, the dose is 1 gram every 8 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. In patients with renal impairment, the dose and/or dosing interval must be adjusted. The duration of therapy depends on the clinical response and the specific infection being treated. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. For infants and children, the dose is typically based on body weight and the specific indication. It is usually administered intravenously every 8 hours. A qualified pediatrician must determine the appropriate dose. |
| Elderly Dosage | Elderly patients may have decreased renal function, which can increase the risk of toxicity. Dose adjustment based on creatinine clearance is recommended. Monitor renal function closely during treatment. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine must be adjusted based on creatinine clearance. For patients with a creatinine clearance of 26-50 mL/min, the usual dose is given every 12 hours. For creatinine clearance of 10-25 mL/min, the usual dose is given every 24 hours. For patients on hemodialysis, the dose is given after each dialysis session. Close monitoring of renal function is essential. |
| Hepatic Impairment | No specific dosage adjustment is recommended for patients with hepatic impairment alone. However, patients with both hepatic and renal impairment should be monitored closely, and dose adjustments may be necessary based on renal function. |
| Maximum Daily Dose | The maximum recommended daily dose is 6 grams per day (2 grams every 8 hours) for serious infections such as meningitis. Doses higher than this are not recommended. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of admero 1gm injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Valproic acid | Major | |
| Probenecid | Major | |
| Aminoglycosides | Moderate | |
| Loop diuretics | Moderate | |
| Warfarin | Moderate | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Valproic acid
- Probenecid
⚡ Moderate Interactions
- Aminoglycosides (e.g., gentamicin)
- Loop diuretics (e.g., furosemide)
- Warfarin
🍷 Alcohol Interaction
There is no known direct interaction between this medicine and alcohol. However, alcohol may worsen side effects such as nausea, vomiting, and dizziness, and can impair recovery from infection. It is advisable to avoid alcohol while receiving treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe hypersensitivity to meropenem or other carbapenem antibiotics","Known severe hypersensitivity to penicillins or cephalosporins (due to potential cross-reactivity)","Concurrent use with valproic acid (due to significant reduction in valproate levels)"]
⚠️ Warnings & Precautions
["Serious allergic reactions, including anaphylaxis, can occur. Discontinue immediately if suspected.","Seizures have been reported, particularly in patients with renal impairment or CNS disorders.","Clostridioides difficile-associated diarrhea can occur and may be severe. Monitor for diarrhea.","Dose adjustment is required in patients with renal impairment.","Prolonged use may lead to superinfection with non-susceptible organisms.","Use with caution in patients with liver disease.","Safety and effectiveness in pediatric patients have been established for certain indications.","Elderly patients may have reduced renal function and require dose adjustment."]
🤱 Lactation Safety
This medicine is excreted in human breast milk in low concentrations. It should be used with caution in breastfeeding women. Consult your doctor to weigh the benefits of breastfeeding against the potential risks to the infant. If used, monitoring the infant for diarrhea, thrush, or allergic reactions is advised.
💊 Overdose Management
Overdose with this medicine is unlikely due to its intravenous administration in a controlled setting. In case of accidental overdose, treatment should be symptomatic and supportive. This medicine is removed by hemodialysis, which may be considered in severe cases. Monitor vital signs and provide appropriate supportive care.
⏰ Missed Dose
Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, it should be administered as soon as possible. However, if it is almost time for the next dose, the missed dose should be skipped, and the regular dosing schedule resumed. Do not double the dose to catch up.
Additional Safety Advice
This medicine must only be given by a qualified healthcare professional in a properly equipped medical facility. Before starting treatment, inform your doctor about all your medical conditions, especially kidney disease, liver disease, central nervous system disorders such as epilepsy, or any allergies to antibiotics. Tell your doctor about all other medicines you are taking, including prescription, over-the-counter, and herbal products, as this medicine can interact with several drugs. Do not breastfeed while receiving this medicine without consulting your doctor, as it may pass into breast milk. If you are pregnant or planning to become pregnant, discuss the risks and benefits with your doctor. During treatment, your doctor may monitor your kidney function, liver function, and blood counts. Report any new or worsening symptoms immediately, especially severe diarrhea, rash, seizures, or signs of an allergic reaction. Do not stop treatment early even if you feel better, as this can lead to incomplete eradication of the infection and promote antibiotic resistance. Always follow your doctor's instructions regarding dose and duration.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can increase the risk of side effects. Dose adjustment based on creatinine clearance is recommended. Monitor renal function closely.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before starting this medicine. It should be used during pregnancy only if clearly needed. Effective contraception is recommended during treatment.
🏥 Post-Surgery Considerations
This medicine is often used to prevent or treat infections after surgery. It is administered intravenously in a hospital setting. Follow your surgeon's instructions regarding wound care and follow-up.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine. It may be used to treat dental infections that are severe, but it is not typically used for routine dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while receiving this medicine, as you may feel weak or dizzy. Light activity is fine if you feel up to it, but consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic, so you may need to take time off work during treatment. You may feel tired or dizzy, so avoid driving or operating heavy machinery until you feel normal.
🛑 When to Stop This Medicine
Do not stop this medicine without your doctor's advice. Complete the full course as prescribed, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance and superinfections. Prolonged therapy requires monitoring of kidney and liver function, as well as blood counts. It should only be used for as long as necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the bacteria causing the infection, other antibiotics such as cephalosporins or fluoroquinolones may be used.
Evidence: Well-establishedFor abscesses, surgical drainage may be necessary in addition to antibiotics.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, it is important to be up to date with recommended vaccines to prevent infections. Live vaccines should be avoided during antibiotic therapy if possible, but consult your doctor.
📦 Storage Guide
✅ DO
Store the unreconstituted vial at room temperature (20-25°C)
❌ DON'T
Do not freeze the vial
✅ DO
Keep in the original packaging
❌ DON'T
Do not use if the packaging is damaged
✅ DO
Use reconstituted solution immediately
❌ DON'T
Do not store reconstituted solution for long periods
✈️ Traveling with This Medicine
This medicine is administered in a healthcare facility, so travel is not typically applicable. If you are traveling after treatment, carry a copy of your prescription and medical records. Store any remaining medication as directed, and declare it at customs if required. Consult your doctor before traveling if you have ongoing medical needs.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Improvement in symptoms may be seen within 24 to 48 hours, but the full course must be completed as prescribed.
A: This medicine may cause dizziness or seizures. Avoid driving until you know how it affects you.
A: This medicine can affect kidney function, especially if you have pre-existing kidney disease. Your doctor will monitor your kidney function and adjust the dose if needed.
🤔 Common Patient Concerns
🔄 Substitutes for admero 1gm injection
View AllAlternative brands with exact same active ingredient:
-
Synthopenam 1000mg InjectionSalud Care India Pvt Ltd ₹21.50 96.7% CHEAPER
-
Swapenem 1000mg InjectionUltratech Pharmaceuticals ₹112.01 82.8% CHEAPER
-
elipenm 1000mg injectionBiophar Lifesciences Pvt Ltd ₹187.50 71.2% CHEAPER
-
ixza 1000mg injectionBiocon ₹371.98 42.9% CHEAPER
-
m penem injectionTroikaa Pharmaceuticals Ltd ₹375.00 42.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken orally.
Fact: This medicine is only available as an intravenous injection and must be given by a healthcare professional. - Myth: This medicine is safe for treating the common cold.
Fact: This medicine is an antibiotic and is ineffective against viral infections like the common cold. - Myth: You can stop this medicine once you feel better.
Fact: You must complete the full course as prescribed to prevent recurrence and resistance.
🔄 Alternative Options
Generic Alternatives
- Meropenem
Brand Alternatives
- Acupenem 1000mg Injection
- Meronem
- Mepenem