Admero 125mg Injection (Meropenem): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing during or after the infusion.
- Sudden severe rash, skin peeling, blisters, or sores in the mouth or eyes.
- Seizure, confusion, or unusual body movements.
- Severe watery diarrhea, fever, or abdominal cramps during or after treatment.
- Unusual bruising or bleeding, or a persistent sore throat with fever.
- Passing much less urine than usual, or swelling of the legs and feet.
- Chest pain, palpitations, or fainting.
- Yellowing of the skin or eyes, or severe abdominal pain.
If experiencing severe symptoms, call emergency services immediately.
What is admero 125mg injection used for?
This medicine is a broad-spectrum intravenous carbapenem antibiotic containing meropenem 125 mg. It is used in hospitals to treat serious bacterial infections such as complicated abdominal infections, urinary tract infections, pneumonia, skin infections, and meningitis. It works by blocking the bacterial cell wall, causing the bacteria to die. It must be given by a healthcare professional and is not for viral infections.
- Generic Name: Meropenem
- Manufacturer: Adjener Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 admero 125mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा मेरोपेनम नामक एंटीबायोटिक है और इसे नस के माध्यम से दिया जाता है। इसका उपयोग अस्पताल में गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है, जैसे पेट के अंदर के संक्रमण, मूत्र मार्ग के जटिल संक्रमण, निमोनिया, त्वचा और मांसपेशियों के गहरे संक्रमण, और कुछ मामलों में मस्तिष्क झिल्ली के संक्रमण में। यह दवा बैक्टीरिया की कोशिका भित्ति को तोड़कर उन्हें मार देती है। यह वायरल बुखार, जुकाम या फ्लू के लिए काम नहीं करती। इसे केवल डॉक्टर की देखरेख में अस्पताल या क्लिनिक में ही दिया जाना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, सिरदर्द, त्वचा पर चकत्ते और इंजेक्शन की जगह पर दर्द या सूजन शामिल हैं। कुछ मामलों में गंभीर एलर्जी, तेज बुखार के साथ दस्त, दौरे पड़ना, खून की गड़बड़ी या गुर्दे की कार्यक्षमता में कमी जैसी गंभीर समस्याएं भी हो सकती हैं। अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, त्वचा का छिलना, या लगातार पानी जैसा दस्त हो, तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा नस के माध्यम से दी जाती है, इसे घर पर खुद से न लगवाएं। इलाज से पहले अपनी सभी एलर्जी, खासकर पेनिसिलिन या सेफलोस्पोरिन से एलर्जी, के बारे में डॉक्टर को जरूर बताएं। अगर आपको गुर्दे या लीवर की बीमारी, मिर्गी, या आंतों की समस्या है, तो डॉक्टर को बताएं। इलाज के दौरान खून की जांचें करवाते रहें। बेहतर महसूस होने पर भी दवा बीच में न रोकें, क्योंकि इससे संक्रमण फिर से हो सकता है। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 admero 125mg injection Uses & Benefits
[{"condition":"Complicated intra-abdominal infections","description":"This medicine is used to treat serious infections inside the abdomen, such as perforated appendicitis, intra-abdominal abscess, and peritonitis, often in combination with surgical drainage.","evidence":"Well-established"},{"condition":"Complicated urinary tract infections","description":"It is used for severe kidney and urinary tract infections, including pyelonephritis, especially when resistant bacteria are suspected or when the patient cannot take oral antibiotics.","evidence":"Well-established"},{"condition":"Hospital-acquired and ventilator-associated pneumonia","description":"This medicine is used for pneumonia that develops during a hospital stay or in patients on breathing machines, where resistant Gram-negative bacteria are common.","evidence":"Well-established"},{"condition":"Complicated skin and soft tissue infections","description":"It treats severe skin infections such as necrotizing fasciitis and diabetic foot infections, usually alongside surgical debridement.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"This medicine is used for certain cases of bacterial meningitis, especially when resistant bacteria are suspected, and it is often combined with other antibiotics.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"It is used as empirical therapy in cancer patients with fever and low white blood cell counts, because it covers a wide range of possible bacteria.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Infections caused by multi-drug resistant organisms","description":"Sometimes used when cultures show bacteria that are resistant to many other antibiotics, based on sensitivity results and specialist advice.","evidence":"Limited"},{"condition":"Cystic fibrosis pulmonary exacerbations","description":"May be used in selected patients with cystic fibrosis and resistant airway infections, guided by culture results.","evidence":"Limited"}]
Primary treatment for: Serious bacterial infections caused by susceptible organisms
Also treats: Complicated intra-abdominal infections, Complicated urinary tract infections, Hospital-acquired pneumonia, Complicated skin and soft tissue infections, Bacterial meningitis, Febrile neutropenia
📋 Drug Information
| Generic Name(s) | Meropenem |
| Brand Name | Acupenem 1000mg Injection |
| Manufacturer | Adjener Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cell wall active agent -Carbapenems |
| Route of Administration | Intravenous (into a vein), as an infusion over a period of time determined by the treating clinician |
| Storage | Store this medicine as directed on the label, usually at controlled room temperature. Protect it from light and moisture. Once reconstituted or diluted, use it within the time specified by the manufacturer and healthcare facility, and do not use it if the solution is cloudy or contains particles. |
| Shelf Life | The shelf life of this medicine is typically 24 to 36 months from the date of manufacture when stored as directed in its original packaging. Once reconstituted or diluted, it should be used within the time specified by the manufacturer and the hospital pharmacy. |
| WHO Guideline | Carbapenem antibiotics such as this medicine are included in the World Health Organization's list of essential medicines and are recommended for serious infections caused by susceptible bacteria, including some multi-drug resistant organisms. The exact choice and duration of therapy should follow local guidelines and the results of culture and sensitivity testing. |
| ICMR Guideline | The Indian Council of Medical Research has published guidance on antimicrobial use that supports the careful, evidence-based use of carbapenems such as this medicine for serious infections, with an emphasis on culture-guided therapy and antimicrobial stewardship to limit resistance. Clinicians should follow the latest ICMR treatment guidelines for the specific infection being treated. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a carbapenem antibiotic that kills bacteria by interfering with the construction of the bacterial cell wall. It binds to penicillin-binding proteins located on the inner membrane of the bacterial cell, which are enzymes involved in cross-linking the peptidoglycan layer of the cell wall. When these enzymes are blocked, the bacterial cell wall becomes weak and unstable, and the bacterium cannot maintain its shape or resist osmotic pressure. This leads to bacterial cell lysis and death. Because carbapenems have a broad spectrum and are stable against many beta-lactamase enzymes, they remain active against many bacteria that would otherwise destroy penicillin-like antibiotics.
Mechanism Steps
💡 How to Take admero 125mg injection
Strength: This medicine is supplied as a sterile powder for injection containing meropenem 125 mg, which is reconstituted and given intravenously.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the type and severity of the infection, the bacteria involved, the patient's kidney function, body weight, and overall health. In adults with normal kidney function, it is commonly given every 8 hours by intravenous infusion, but the exact dose and duration must be determined by the treating doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific 125 mg presentation. Doses in children are based on body weight and the type of infection, and must be determined by a pediatrician or pediatric infectious disease specialist. Do not use this medicine in children without specialist supervision. |
| Elderly Dosage | Older adults may need a lower dose or longer dosing interval because kidney function often declines with age. Kidney function should be checked before and during treatment, and the dose must be individualized by a qualified clinician. |
| Renal Impairment | The dose and dosing interval of this medicine must be adjusted in patients with reduced kidney function. Your doctor will check your kidney function with blood tests and may reduce the dose or give it less often. In patients on dialysis, the timing of doses may need to be coordinated with dialysis sessions. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | Mild to moderate liver disease usually does not require a dose change for this medicine, because it is mainly eliminated by the kidneys. However, patients with severe liver disease should be monitored closely, and the dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose of this medicine depends on the infection being treated, the patient's kidney function, and the treating doctor's judgment. It should never exceed the dose prescribed by your clinician. For educational reference only, adult doses are commonly given every 8 hours, but the exact maximum must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of admero 125mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Valproic acid | Major | |
| Probenecid | Major | |
| Aminoglycosides | Moderate | |
| Vancomycin | Moderate | |
| Amphotericin B | Moderate | |
| Warfarin | Moderate | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Valproic acid and divalproex sodium
- Probenecid
⚡ Moderate Interactions
- Other nephrotoxic drugs such as aminoglycosides, amphotericin B, or vancomycin
- Warfarin and other anticoagulants
🍷 Alcohol Interaction
Alcohol is not known to interact directly with this medicine, but drinking alcohol while you are being treated for a serious infection can worsen dehydration, interfere with recovery, and increase the risk of liver problems. It is best to avoid alcohol until your doctor says it is safe.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergy to meropenem or any other carbapenem antibiotic","Known severe immediate-type hypersensitivity to penicillin or cephalosporin antibiotics, due to possible cross-reactivity","Use of valproic acid or divalproex sodium, because this medicine can reduce their levels and increase seizure risk"]
⚠️ Warnings & Precautions
["Serious allergic reactions, including anaphylaxis, can occur; stop the infusion and seek emergency care if this happens.","Clostridioides difficile-associated diarrhea can develop during or after treatment; report watery diarrhea, fever, or abdominal cramps.","Seizures have been reported, especially in patients with kidney impairment or pre-existing seizure disorders; use with caution in these groups.","Kidney function should be monitored, and the dose adjusted in patients with reduced kidney function.","Liver function should be monitored during prolonged treatment.","This medicine should be used only for bacterial infections and not for viral illnesses such as the common cold or flu.","Complete the full course as prescribed by your doctor to reduce the risk of resistance and relapse."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is usually considered compatible with breastfeeding when the mother needs it for a serious infection, but the baby should be monitored for diarrhea, thrush, or rash. Discuss with your doctor before breastfeeding while receiving this medicine.
💊 Overdose Management
Overdose with this medicine is unlikely because it is given by healthcare professionals in a controlled setting. If too much is given, the main concern is an increased risk of nausea, vomiting, diarrhea, seizures, and kidney problems. Treatment is supportive, with close monitoring of vital signs, kidney function, and neurological status. In patients with kidney failure, hemodialysis may help remove the drug from the body. There is no specific antidote.
⏰ Missed Dose
Because this medicine is given by a healthcare professional in a hospital or clinic, a missed dose is usually managed by the medical team. If you miss an appointment for your infusion, contact your doctor or clinic as soon as possible to reschedule. Do not try to catch up by taking extra doses on your own, and do not change the schedule without medical advice.
Additional Safety Advice
This medicine must only be given by a healthcare professional in a hospital or clinic setting, and it should never be self-administered at home. Before treatment starts, tell your doctor about all your allergies, especially any allergy to penicillin, cephalosporin, or carbapenem antibiotics, because a serious allergic reaction is possible. Inform your doctor if you have kidney disease, liver disease, epilepsy or any seizure disorder, or a history of gastrointestinal problems such as colitis, because the dose or monitoring may need to be adjusted. Do not stop or change the treatment on your own, even if you feel better, because stopping antibiotics too early can allow the infection to return and can encourage bacterial resistance. If you develop a rash, swelling of the face or throat, difficulty breathing, severe diarrhea, or unusual bruising or bleeding, seek medical help immediately. While receiving this medicine, your doctor may order blood tests to check your kidney function, liver function, and blood cell counts, and it is important to attend these tests. If you are pregnant, planning pregnancy, or breastfeeding, tell your doctor so that the benefits and risks can be discussed. Keep all follow-up appointments so that the response to treatment can be assessed properly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to have reduced kidney function, which can increase the blood levels of this medicine and the risk of side effects such as seizures and confusion. Kidney function should be checked before and during treatment, and the dose should be adjusted accordingly. Elderly patients should also be monitored for falls, dehydration, and interactions with other medicines.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss this with your doctor before starting treatment. This medicine is generally used in pregnancy only when there is a clear medical need for a serious bacterial infection. Your doctor will weigh the benefits and risks for you and your baby. If you become pregnant during treatment, inform your doctor immediately.
🏥 Post-Surgery Considerations
This medicine is often used after surgery to treat or prevent serious infections. After surgery, the dose and duration will depend on the type of operation, the infection risk, and your kidney function. Keep the surgical wound clean and dry, and report any increasing pain, redness, swelling, or discharge to your doctor.
🦷 Dental Procedures
Tell your dentist and doctor that you are receiving this medicine before any dental procedure. In general, this medicine is not used for routine dental infections, but if you have a serious infection, your dental treatment may need to be coordinated with your medical team. Good oral hygiene is important during recovery.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While you are receiving this medicine for a serious infection, you should avoid strenuous exercise and heavy lifting. Gentle movement and short walks may be helpful once you are stable, but always follow your doctor's advice. If you feel dizzy, breathless, or weak, stop and rest.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic, so you will likely need time off work during treatment. You may feel tired, weak, or drowsy, and you should not drive or operate heavy machinery until you feel fully alert and your doctor says it is safe. Once the infection is controlled and you are discharged, you can gradually return to your normal activities as advised.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when to stop based on your clinical improvement, laboratory results, and the specific infection being treated. If you develop a serious side effect such as a severe allergic reaction, severe diarrhea, or a seizure, the medical team will stop the medicine and manage the reaction. Always ask your doctor before stopping or changing treatment.
📅 Long-Term Use Effects
This medicine is usually given for a limited period, so long-term effects are uncommon. Prolonged or repeated use can increase the risk of antibiotic resistance, fungal infections, and Clostridioides difficile-associated diarrhea. Kidney and liver function should be monitored during longer courses, and blood counts may be checked if treatment continues for more than a few days. If you need repeated courses, your doctor will review the need and may look for other treatment options.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Once the bacteria and their sensitivity are known, your doctor may switch to a narrower antibiotic that is equally effective and safer for you.
Evidence: Well-establishedFor some infections, such as abscesses, surgical drainage or removal of infected tissue is essential along with antibiotics.
Evidence: Well-establishedRest, fluids, fever control, and nutrition support recovery while the antibiotic works.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines, but if you are seriously ill, vaccination may be postponed until you recover. Live vaccines should generally be avoided during severe illness and while on intensive treatment. Discuss the timing of any vaccine with your doctor.
📦 Storage Guide
✅ DO
Store this medicine as directed on the label, usually at controlled room temperature.
❌ DON'T
Do not freeze or expose it to excessive heat.
✅ DO
Keep it in its original packaging until it is prepared for use.
❌ DON'T
Do not transfer it to unmarked containers.
✅ DO
Protect it from light and moisture.
❌ DON'T
Do not store it in a bathroom or near a sink.
✅ DO
Use reconstituted or diluted solution within the time specified by the manufacturer.
❌ DON'T
Do not use a solution that is cloudy or contains particles.
✈️ Traveling with This Medicine
This medicine is given intravenously in a hospital or clinic, so travel while receiving treatment is usually not advised until your doctor says you are stable. If you must travel after treatment, carry a copy of your prescription and discharge summary, keep the medicine in its original packaging if you are carrying it, and store it as directed. Check the laws of your destination country about carrying prescription medicines, and carry enough supply for your trip. If you are traveling across time zones and still need treatment, ask your doctor how to adjust the timing of doses. Always keep your emergency contact information and medical records with you.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antibacterial effect starts soon after the infusion, but you may notice improvement in fever, pain, and general well-being within 24 to 72 hours. The full course must be completed as prescribed.
A: No. This medicine is given intravenously in a hospital or clinic by a healthcare professional. It is not for self-administration at home.
A: It can be used, but the dose and dosing interval must be adjusted based on your kidney function. Your doctor will monitor your kidney tests during treatment.
A: No. Stopping early can allow the infection to return and can increase antibiotic resistance. Always follow your doctor's instructions about the duration of treatment.
A: Yes, it can interact with some medicines, especially valproic acid, probenecid, and other drugs that affect the kidneys. Always tell your doctor about all medicines you take.
🤔 Common Patient Concerns
🔄 Substitutes for admero 125mg injection
View AllAlternative brands with exact same active ingredient:
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merous 125mg injectionIva Healthcare Pvt. Ltd. ₹123.75 11% CHEAPER
-
merosure 125mg injectionAlkem Laboratories Ltd ₹135.94 2.2% CHEAPER
-
merotoss 125mg injectionNovalab Healthcare Pvt Ltd ₹136.88 1.5% CHEAPER
-
micropenam 125mg injectionMicro Labs Ltd ₹137.50 1.1% CHEAPER
-
merotrol 125mg injectionLupin Ltd ₹139.69 0.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any fever.
Fact: This medicine only treats certain bacterial infections and is not effective against viral fevers such as the common cold or flu. - Myth: This medicine can be taken as an oral tablet.
Fact: This medicine is given intravenously in a hospital or clinic setting and is not available as an oral tablet. - Myth: You can stop this medicine as soon as you feel better.
Fact: Stopping early can allow the infection to return and can promote antibiotic resistance. Always follow your doctor's instructions. - Myth: This medicine is safe to use without monitoring.
Fact: Kidney function, liver function, and blood counts should be monitored during treatment, especially in high-risk patients.
🔄 Alternative Options
Generic Alternatives
- Meropenem 125 mg injection
Brand Alternatives
- Admero 125mg injection