Acimero 125mg Injection (Meropenem): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe diarrhea with blood or mucus
- Seizures or confusion
- Decreased urine output or swelling
- Unusual bleeding or bruising
- Persistent high fever despite treatment
If experiencing severe symptoms, call emergency services immediately.
What is micropenam 125mg injection used for?
This medicine is a broad-spectrum intravenous antibiotic used to treat serious bacterial infections. It works by killing bacteria and is administered by a healthcare professional.
- Generic Name: Meropenem (125mg)
- Manufacturer: Micro Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 micropenam 125mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा मेरोपेनम नामक एंटीबायोटिक है, जिसका उपयोग गंभीर जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह पेट, फेफड़े, मस्तिष्क, मूत्र मार्ग और त्वचा के संक्रमणों में प्रभावी है। यह केवल अस्पताल में डॉक्टर या नर्स द्वारा नस के माध्यम से दी जाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, सिरदर्द, चकत्ते और इंजेक्शन स्थल पर सूजन शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, दौरे और आंतों का संक्रमण हो सकता है।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा अस्पताल में दी जानी चाहिए। अपनी सभी एलर्जी के बारे में डॉक्टर को बताएं। गुर्दे की समस्या होने पर खुराक समायोजित की जा सकती है। बिना डॉक्टर की सलाह के दवा बंद न करें।
💊 micropenam 125mg injection Uses & Benefits
[{"condition":"Complicated intra-abdominal infections","description":"Used to treat serious infections within the abdomen, such as peritonitis and abscesses.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"Effective against meningitis caused by susceptible bacteria, including in pediatric patients.","evidence":"Well-established"},{"condition":"Community-acquired pneumonia","description":"Used for severe cases requiring hospitalization and intravenous antibiotics.","evidence":"Well-established"},{"condition":"Complicated urinary tract infections","description":"Treats severe kidney and urinary tract infections caused by resistant bacteria.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"Empiric therapy for fever in patients with low white blood cell counts.","evidence":"Well-established"},{"condition":"Complicated skin and skin structure infections","description":"Used for severe skin infections including diabetic foot infections.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Nocardiosis","description":"Sometimes used as an alternative treatment for Nocardia infections.","evidence":"Limited"},{"condition":"Melioidosis","description":"May be used in the treatment of Burkholderia pseudomallei infections.","evidence":"Limited"}]
Primary treatment for: Serious bacterial infections
Also treats: Intra-abdominal infections, Meningitis, Pneumonia, Urinary tract infections, Febrile neutropenia, Skin infections
📋 Drug Information
| Generic Name(s) | Meropenem (125mg) |
| Brand Name | micropenam 125mg injection |
| Manufacturer | Micro Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cell wall active agent -Carbapenems |
| Route of Administration | Parenteral (intravenous injection or infusion) |
| Storage | Store vials at 20-25°C (68-77°F). After reconstitution, store at room temperature and use within specified time (e.g., 1 hour for intravenous bolus, 4 hours for infusion). Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Meropenem is included in the WHO Model List of Essential Medicines for the treatment of serious bacterial infections. |
| ICMR Guideline | ICMR guidelines recommend meropenem for the treatment of hospital-acquired infections and severe community-acquired infections based on culture sensitivity. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Meropenem exerts its bactericidal action by binding to penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the cross-linking of peptidoglycan chains, which are essential for cell wall integrity. The result is a weakened cell wall that leads to cell lysis and death, especially in rapidly dividing bacteria.
Mechanism Steps
💡 How to Take micropenam 125mg injection
Strength: 125mg injection (powder for reconstitution).
Dosage Information
| Adult Dosage | The usual adult dose is 500 mg to 1 g every 8 hours by intravenous infusion, depending on the type and severity of infection. For meningitis, 2 g every 8 hours is recommended. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | For infants and children, dosing is weight-based and varies by indication. Typical doses range from 10 mg/kg to 40 mg/kg every 8 hours. Pediatric dosing is not established from available information for all indications. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function; dose adjustment based on creatinine clearance is recommended. No specific dose adjustment for age alone. |
| Renal Impairment | Dose adjustment is required for patients with creatinine clearance less than 50 mL/min. For CrCl 26-50 mL/min: usual dose every 12 hours; for CrCl 10-25 mL/min: half usual dose every 12 hours; for CrCl <10 mL/min: half usual dose every 24 hours. Consult a clinician for precise dosing. |
| Hepatic Impairment | No dose adjustment is necessary for hepatic impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is 6 g (e.g., 2 g every 8 hours). |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of micropenam 125mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Probenecid | Major | |
| Valproic acid | Major | |
| Aminoglycosides | Moderate | |
| Warfarin | Moderate | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Probenecid
- Valproic acid
⚡ Moderate Interactions
- Aminoglycosides
- Warfarin
🍷 Alcohol Interaction
No specific interaction is established, but alcohol may worsen side effects like nausea and dizziness. It is advisable to avoid alcohol during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to meropenem or other carbapenems","Severe allergy to penicillins or cephalosporins (cross-reactivity)","Concurrent use with valproic acid"]
⚠️ Warnings & Precautions
["Serious hypersensitivity reactions, including anaphylaxis, have been reported.","Clostridium difficile-associated diarrhea may occur; monitor for persistent diarrhea.","Seizures have been reported, especially in patients with renal impairment.","Dose adjustment is required in patients with renal impairment.","Prolonged use may lead to superinfection with non-susceptible organisms.","Not for intramuscular or subcutaneous administration."]
🤱 Lactation Safety
Meropenem is excreted in human milk in low amounts. Caution is advised; consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and seizures. Treatment is symptomatic and supportive. Meropenem is dialyzable; hemodialysis may be considered in severe cases.
⏰ Missed Dose
This medicine is administered by a healthcare professional. If a dose is missed, contact your healthcare provider immediately. Do not attempt to self-administer.
Additional Safety Advice
This medicine must be administered only by a qualified healthcare professional in a hospital or clinic setting. Inform your doctor about any allergies, especially to penicillins or cephalosporins, before receiving this medicine. Report any signs of allergic reaction such as rash, itching, swelling, or difficulty breathing immediately. Use caution if you have kidney problems, as dose adjustment may be needed. Do not use this medicine for viral infections like the common cold or flu. Complete the full course as prescribed by your doctor to prevent resistance.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced renal function and may require dose adjustment. Monitor closely for side effects.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. Use only if clearly needed.
🏥 Post-Surgery Considerations
This medicine is often used to prevent or treat surgical site infections. Follow your surgeon's instructions.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine. It may be used prophylactically for certain dental procedures in high-risk patients.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Rest is advised during acute infection. Gradually resume activities as you recover. Avoid strenuous exercise until cleared by your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
During treatment, you may need to be hospitalized. Driving and operating machinery should be avoided if you feel dizzy or unwell. Recovery time varies.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Complete the full course as prescribed, even if you feel better.
📅 Long-Term Use Effects
Long-term use may lead to antibiotic resistance and superinfections. Prolonged therapy requires monitoring of renal and hepatic function, and blood counts. Use for the shortest effective duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on culture results, other antibiotics may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines. However, antibiotics may affect the immune response to live vaccines. Consult your doctor.
📦 Storage Guide
✅ DO
Store vials at room temperature (20-25°C)
❌ DON'T
Do not freeze
✅ DO
Use reconstituted solution within specified time
❌ DON'T
Do not store reconstituted solution for extended periods
✅ DO
Keep in original packaging
❌ DON'T
Do not use if solution is discolored or contains particles
✈️ Traveling with This Medicine
This medicine is administered in a healthcare setting and is not for self-administration during travel. If you are traveling and need this medicine, ensure you have a prescription and arrange for administration at a medical facility. Carry your prescription and medical records. Store vials as directed and protect from extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Improvement in symptoms may be seen within 24-48 hours, but complete recovery depends on the infection and may take several days.
A: No, this medicine is given intravenously only.
A: It is classified as Pregnancy Category B. Use only if clearly needed, as advised by your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for micropenam 125mg injection
View AllAlternative brands with exact same active ingredient:
-
merous 125mg injectionIva Healthcare Pvt. Ltd. ₹123.75 10% CHEAPER
-
merosure 125mg injectionAlkem Laboratories Ltd ₹135.94 1.1% CHEAPER
-
merotoss 125mg injectionNovalab Healthcare Pvt Ltd ₹136.88 0.5% CHEAPER
-
admero 125mg injectionAdjener Pharmaceuticals Pvt Ltd ₹139.00 1.1% COSTLIER
-
merotrol 125mg injectionLupin Ltd ₹139.69 1.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken orally.
Fact: This medicine is an injection and must be given intravenously by a healthcare professional. - Myth: This medicine is safe for everyone.
Fact: It is contraindicated in patients with known hypersensitivity to carbapenems and should be used with caution in those with penicillin allergy.
🔄 Alternative Options
Generic Alternatives
- Meropenem 125mg injection (various manufacturers)
Brand Alternatives
- Meronem
- Merocrit
- Meropen
- Meroza