adiflam 50mg injection - Diclofenac (50mg) medicine

Adiflam 50mg Tablet: Complete Medicine Guide

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🏭 Leben Life Sciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. However, this medicine is generally avoided during pregnancy, especially in the third trimester, due to risk of premature closure of the ductus arteriosus and other complications. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term pain and inflammation relief.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising
  • Severe dizziness or fainting

If experiencing severe symptoms, call emergency services immediately.

What is adiflam 50mg injection used for?

This medicine is an oral NSAID containing Diclofenac 50mg. It is used for short-term relief of pain and inflammation in conditions like arthritis, gout, and injuries. It works by blocking COX enzymes. Take it with food, avoid alcohol, and do not exceed 150 mg per day.

  • Generic Name: Diclofenac
  • Manufacturer: Leben Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 adiflam 50mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा डिक्लोफेनाक 50 मिलीग्राम की एक ओरल टैबलेट है, जो नॉनस्टेरॉइडल एंटी-इंफ्लेमेटरी ड्रग (NSAID) श्रेणी में आती है। इसका उपयोग जोड़ों के दर्द, सूजन, अकड़न, गठिया, गाउट, मांसपेशियों की चोट, दांत दर्द, और मासिक धर्म के दर्द में राहत के लिए किया जाता है। यह दर्द और सूजन पैदा करने वाले प्रोस्टाग्लैंडिन को कम करके काम करती है। इसे डॉक्टर की सलाह के अनुसार ही लें, खासकर खाने के साथ, ताकि पेट में जलन न हो। लंबे समय तक इसका इस्तेमाल न करें क्योंकि इससे पेट में ब्लीडिंग, किडनी और हृदय संबंधी समस्याएं हो सकती हैं। गर्भवती महिलाओं, किडनी या लीवर की गंभीर बीमारी वालों, और पेट के अल्सर वालों को इसका सेवन नहीं करना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में पेट दर्द, जलन, मतली, उल्टी, दस्त, कब्ज, गैस, सिरदर्द, चक्कर आना और हल्के दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें पेट या आंतों में ब्लीडिंग, अल्सर, किडनी की समस्या, लीवर की क्षति, गंभीर एलर्जी, और दिल का दौरा या स्ट्रोक का खतरा बढ़ सकता है। अगर काला या खूनी मल, खून की उल्टी, गंभीर पेट दर्द, सीने में दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, आंखों या त्वचा का पीलापन, या पेशाब कम आना जैसे लक्षण दिखें, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा न बढ़ाएं और न ही लंबे समय तक लें। इसे खाने के साथ या दूध के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे पेट में ब्लीडिंग का खतरा बढ़ सकता है। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें। अगर आपको दिल, किडनी, लीवर या पेट की समस्या है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान बिना डॉक्टर की सलाह के इसका सेवन न करें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 adiflam 50mg injection Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps relieve back pain and stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute gout","description":"Reduces pain and inflammation during acute gout attacks.","evidence":"Well-established"},{"condition":"Musculoskeletal injuries","description":"Provides short-term relief for sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Postoperative pain","description":"Used for short-term management of mild to moderate postoperative pain.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Used for short-term relief of dental pain and inflammation.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Pericarditis","description":"May be used off-label for pain relief in pericarditis under specialist care.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation associated with musculoskeletal and joint conditions

Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute gout, Dysmenorrhea, Postoperative pain, Dental pain

📋 Drug Information

Generic Name(s)Diclofenac
Brand NameAdiflam 50mg Tablet
ManufacturerLeben Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach upset.
2
Use the lowest effective dose for the shortest duration possible.
3
Avoid alcohol completely while taking this medicine to prevent stomach bleeding.
4
Do not take other NSAIDs or pain relievers without consulting your doctor.
5
If you have heart, kidney, liver, or stomach problems, inform your doctor before starting this medicine.
6
Report any unusual bleeding, bruising, or black stools immediately.
7
Stay well hydrated throughout the day to support kidney function.
8
Do not use this medicine for more than 7 days without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Menstrual cramps
This medicine can relieve dysmenorrhea.
Likely Use
Dental pain
This medicine can provide short-term relief.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and completely absorbed from the gastrointestinal tract after oral administration. Food may delay absorption but does not significantly reduce the extent of absorption.
DistributionThis medicine is highly bound to plasma proteins and distributes widely into body tissues, especially inflamed areas. It crosses the placenta and is excreted in breast milk in small amounts.
Protein BindingGreater than 99% bound to plasma proteins, primarily albumin.
MetabolismThis medicine is extensively metabolized in the liver, primarily by cytochrome P450 enzymes CYP2C9 and CYP3A4, into several metabolites, some of which are active.
Half-LifeThe elimination half-life is approximately 1 to 2 hours.
ExcretionMetabolites are excreted mainly in the urine (about 65%) and bile/feces (about 35%).
BioavailabilityThe oral bioavailability is approximately 50% to 60% due to first-pass metabolism.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached about 2 to 3 hours after oral administration.
Duration of ActionThe analgesic and anti-inflammatory effects last approximately 4 to 6 hours, so dosing is usually every 6 to 8 hours as needed.

How It Works

This medicine works by inhibiting the cyclooxygenase (COX) enzymes, primarily COX-1 and COX-2, which are responsible for converting arachidonic acid into prostaglandins and thromboxanes. Prostaglandins are key mediators of pain, inflammation, and fever. By blocking their production, this medicine reduces pain, swelling, and stiffness. It also has antipyretic properties, though it is not primarily used as a fever reducer.

Mechanism Steps

1
Absorption and distribution: After oral intake, this medicine is absorbed in the gastrointestinal tract and distributed throughout the body, reaching inflamed tissues.
2
COX enzyme inhibition: This medicine binds to and inhibits both COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandins.
3
Reduced prostaglandin synthesis: Lower prostaglandin levels lead to decreased pain signaling, reduced inflammation, and less fever.
4
Clinical effects: The patient experiences relief from pain, swelling, and stiffness, with effects lasting several hours.

💡 How to Take adiflam 50mg injection

Strength: Immediate-release tablet, 50 mg

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take it with food or milk to reduce stomach upset.
4Do not crush, chew, or break the tablet unless advised by your doctor.
5Follow the dosing schedule recommended by your doctor.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose for pain and inflammation is 50 mg two to three times daily, not exceeding 150 mg per day. For osteoarthritis and rheumatoid arthritis, the dose may be 50 mg two to three times daily or 75 mg twice daily. For acute gout, an initial dose of 100 mg followed by 50 mg three times daily is sometimes used. For dysmenorrhea, 50 mg three times daily may be prescribed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Use the lowest effective dose for the shortest duration.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients are at increased risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney function and for signs of bleeding. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with mild to moderate kidney impairment, dose adjustment may not be necessary, but caution is advised. In severe kidney impairment, this medicine is contraindicated. Consult your doctor for individualized dosing.
Hepatic ImpairmentIn patients with mild to moderate liver impairment, dose adjustment may not be necessary, but caution is advised. In severe liver impairment, this medicine is contraindicated. Consult your doctor for individualized dosing.
Maximum Daily Dose150 mg per day for adults. Do not exceed this dose without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.
Grapefruit juice
Avoid or limit
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of adiflam 50mg injection

✅ Common Side Effects

Stomach pain (Common (5-10%))
Take with food or milk. If pain persists, consult your doctor.
Heartburn (Common (5-10%))
Avoid spicy foods and alcohol. Consult doctor if it continues.
Nausea (Common (5-10%))
Take with a meal. If vomiting occurs, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Peptic ulcer (Rare (<0.1%))
Report persistent stomach pain or indigestion to your doctor immediately.
Kidney impairment (Rare (<0.1%))
Seek medical help if you notice decreased urine output, swelling, or fatigue.
Liver damage (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor.
Severe allergic reaction (Rare (<0.1%))
Seek emergency care if you experience swelling of face, lips, throat, or difficulty breathing.
Cardiovascular events (Rare (<0.1%))
Seek immediate help for chest pain, shortness of breath, or weakness on one side of the body.

⚠️ Rare Side Effects

Aseptic meningitis
Seek immediate medical attention for severe headache, stiff neck, and fever.
Pancreatitis
Go to the emergency room if you have severe upper abdominal pain radiating to your back.
Stevens-Johnson syndrome
Seek emergency care for rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Aspirin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Lithium Major
ACE inhibitors Major
Diuretics Major
SSRIs Moderate
Cyclosporine Moderate

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Other NSAIDs
  • Corticosteroids
  • Methotrexate
  • Lithium
  • ACE inhibitors
  • Diuretics

⚡ Moderate Interactions

  • SSRIs
  • Cyclosporine
  • Tacrolimus
  • Zidovudine
  • Quinolone antibiotics

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of stomach bleeding, ulcers, and liver problems. It can also worsen dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney disease","Severe liver disease","History of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs","Third trimester of pregnancy","Coronary artery bypass graft (CABG) surgery perioperative period"]

⚠️ Warnings & Precautions

["Take with food or milk to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not use for longer than prescribed without medical advice.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of heart, kidney, liver, or stomach problems.","Do not take other NSAIDs or pain relievers without consulting your doctor.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Stop use and seek medical help if you experience signs of allergic reaction, bleeding, or severe abdominal pain."]

🤱 Lactation Safety

This medicine is excreted in breast milk in small amounts. It is generally considered safe for short-term use during breastfeeding, but consult your doctor to weigh benefits and risks.

💊 Overdose Management

Overdose may cause nausea, vomiting, abdominal pain, gastrointestinal bleeding, drowsiness, and in severe cases, kidney failure or seizures. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be used if overdose is recent. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than advised. Take it with food or milk to reduce stomach upset. Avoid alcohol because it can increase the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. If you have heart, kidney, liver, or stomach problems, tell your doctor before starting this medicine. Use the lowest effective dose for the shortest possible time. Do not use this medicine if you are pregnant, especially after 30 weeks, or breastfeeding without medical advice. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney function and for signs of bleeding. Avoid long-term use unless clearly necessary.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, avoid this medicine as it may affect ovulation and early pregnancy. Consult your doctor for alternative pain relief options. Do not use this medicine during pregnancy, especially in the third trimester, unless advised by a doctor.

🏥 Post-Surgery Considerations

This medicine may be used for short-term postoperative pain relief. However, it can increase bleeding risk and may interfere with bone healing. Consult your surgeon before using it after surgery.

🦷 Dental Procedures

This medicine can be used for dental pain, but inform your dentist if you are taking it before any dental procedure, as it may increase bleeding risk. Your dentist may advise stopping it temporarily before surgery.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture to prevent musculoskeletal strain.
💧
Include anti-inflammatory foods like omega-3 rich fish, fruits, and vegetables.
🧘
Get adequate sleep to support recovery.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may cause injury while taking this medicine, as it can mask pain and lead to overexertion. Consult your doctor before starting any new exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods like salmon, flaxseeds, and walnuts.
Reduce processed and fried food intake.
Stay well hydrated by drinking plenty of water.
Eat a balanced diet rich in fruits and vegetables.
Limit alcohol and caffeine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Generally, it does not significantly impact daily activities when taken as prescribed.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe stomach pain, black stools, vomiting blood, signs of allergic reaction, or any other serious side effects. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver damage, and cardiovascular events such as heart attack and stroke. Regular monitoring of kidney and liver function, blood pressure, and signs of bleeding is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor if you need to use it for more than a few days.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve joint function.

Evidence: Well-established
Heat and cold therapy

May help reduce pain and inflammation in localized areas.

Evidence: Limited
Acupuncture

Some evidence for pain relief in chronic conditions.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine. There is no need to postpone vaccination unless advised by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture and heat. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep a list of your medications and allergies with you.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with acute gout attack
Took this medicine for severe toe pain and swelling. Pain relief began within an hour. He was advised to avoid alcohol and to monitor for stomach upset. He recovered well without complications.
💡 Lesson: Early use during acute gout attacks can provide rapid relief, but short-term use and monitoring are essential.
👤 A 30-year-old woman with menstrual cramps
Used this medicine for dysmenorrhea. It relieved cramps effectively, but she experienced mild heartburn. Taking it with food helped reduce the discomfort.
💡 Lesson: Taking with food can minimize gastrointestinal side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 30 to 60 minutes after taking this medicine.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe during pregnancy?

A: It is generally avoided during pregnancy, especially in the third trimester, unless advised by your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for adiflam 50mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe to take long-term without monitoring.
    Fact: Long-term use can cause stomach bleeding, kidney problems, and heart issues. Regular monitoring is needed.
  • Myth: This medicine can be taken on an empty stomach.
    Fact: It should be taken with food or milk to reduce stomach upset.
  • Myth: This medicine is safe to take with other pain relievers.
    Fact: Combining with other NSAIDs increases the risk of side effects. Consult your doctor.
  • Myth: This medicine is safe during pregnancy.
    Fact: It is generally avoided during pregnancy, especially in the third trimester, unless advised by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Diclofenac 50mg tablet

Brand Alternatives

  • Adiflam 50mg tablet
  • Voveran 50mg tablet
  • Diclomol 50mg tablet
  • Nac 50mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Diclofenac 50mg","class":"NSAID","half_life":"1-2 hours","common_uses":"Arthritis, gout, injuries","gi_risk":"Moderate to high"},{"medicine":"Ibuprofen 400mg","class":"NSAID","half_life":"2 hours","common_uses":"Pain, fever, inflammation","gi_risk":"Moderate"},{"medicine":"Naproxen 250mg","class":"NSAID","half_life":"12-17 hours","common_uses":"Arthritis, pain","gi_risk":"Moderate to high"}]

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