adicoff p syrup - Chlorpheniramine Maleate (NA) + Bromhexine (NA) medicine

Adicoff P Syrup - Uses, Price, Side Effects

4.7 (14 reviews)
๐Ÿญ Admit Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is adicoff p syrup used for?

Adicoff P Syrup is a combination medicine used to relieve cough and congestion. It contains Chlorpheniramine Maleate, an antihistamine that reduces allergy symptoms, and Bromhexine, a mucolytic that thins mucus, making it easier to cough up. It is typically taken twice daily after meals.

  • Generic Name: Chlorpheniramine Maleate + Bromhexine
  • Manufacturer: Admit Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š adicoff p syrup Uses & Benefits

Symptomatic relief of cough associated with allergies, colds, and respiratory tract infections.

Off-label uses: Not commonly used off-label.

๐Ÿ“‹ Drug Information

Generic Name(s)Chlorpheniramine Maleate + Bromhexine
Brand NameAdicoff P Syrup
ManufacturerAdmit Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Expectorant
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract.
DistributionWidely distributed in body tissues.
Protein BindingChlorpheniramine: ~70%; Bromhexine: ~90%
MetabolismHepatic metabolism via CYP450 enzymes.
Half-LifeChlorpheniramine: 12-15 hours; Bromhexine: 12-22 hours
ExcretionRenal excretion of metabolites.
BioavailabilityChlorpheniramine: ~50%; Bromhexine: ~75%
Onset of Action30-60 minutes
Peak Plasma Time2-6 hours
Duration of Action4-6 hours

How It Works

Chlorpheniramine blocks histamine H1 receptors, reducing allergic symptoms; Bromhexine increases respiratory tract secretions and reduces mucus viscosity.

Mechanism Steps

1Chlorpheniramine competitively blocks H1 receptors, preventing histamine-mediated effects.
2Bromhexine depolymerizes mucopolysaccharides, reducing sputum viscosity.
3Increased respiratory tract secretions facilitate expectoration.

๐Ÿ’ก How to Take adicoff p syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of adicoff p syrup

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Dizziness
  • Nausea
  • Headache

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction
  • Respiratory depression
  • Arrhythmias
  • Seizures

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Hepatotoxicity
  • Hypotension

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAO Inhibitors Major Hypertensive crisis
Alcohol Moderate Increased sedation
CNS Depressants Moderate Additive sedative effect

๐Ÿšจ Major Interactions

  • MAOIs
  • CNS depressants
  • Alcohol

โšก Moderate Interactions

  • Anticholinergics
  • Tricyclic antidepressants

โ„น๏ธ Minor Interactions

  • Antihypertensives
  • Diuretics

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Increased CNS depression and sedation.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe hypertension, coronary artery disease, MAOI use within 14 days.

๐Ÿ“Š Monitoring Parameters

Monitor for sedation, anticholinergic effects, and respiratory status.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Induce vomiting or gastric lavage; administer activated charcoal; supportive care for CNS depression and anticholinergic effects.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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