adcloz 0.5mg tablet md - Clonazepam (0.5mg) medicine

Adcloz 0.5mg Tablet MD - Uses, Price, Side Effects

4.6 (14 reviews)

Clonazepam (0.5mg)

🏭 Atral Cyrus Lifesciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is adcloz 0.5mg tablet md used for?

Adcloz 0.5mg Tablet MD contains Clonazepam, a benzodiazepine used to treat anxiety disorders, panic attacks, and certain types of seizures. It works by enhancing the effect of GABA, a natural chemical in the brain that promotes calmness and reduces abnormal electrical activity. This medicine helps control symptoms and improve daily functioning.

Generic Name: Clonazepam
Manufacturer: Atral Cyrus Lifesciences
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 adcloz 0.5mg tablet md Uses & Benefits

Panic disorder, seizure disorders (e.g., Lennox-Gastaut syndrome, myoclonic seizures), anxiety disorders, REM sleep behavior disorder.

Off-label uses: Bipolar disorder (mania), restless legs syndrome, tinnitus, stiff-person syndrome.

📋 Drug Information

Generic Name(s)	Clonazepam
Brand Name	Anxipam
Manufacturer	Atral Cyrus Lifesciences
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Benzodiazepines
Route of Administration	Oral
Storage	Store at room temperature (20-25°C), protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; peak plasma concentrations achieved within 1-4 hours.

DistributionWidely distributed throughout the body; crosses the blood-brain barrier and placenta.

Protein BindingApproximately 85% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP3A4 to inactive metabolites (mainly 7-aminoclonazepam).

Half-Life30-40 hours

ExcretionPrimarily renal excretion of metabolites; less than 2% excreted unchanged.

Bioavailability90%

Onset of Action30-60 minutes

Peak Plasma Time1-4 hours

Duration of Action6-12 hours (for single dose); longer with repeated dosing due to accumulation.

How It Works

Enhances GABA-mediated inhibition by binding to benzodiazepine site on GABA-A receptors, increasing chloride ion conductance.

Mechanism Steps

1Binds to benzodiazepine site on GABA-A receptor

2Increases affinity of GABA for the receptor

3Enhances chloride ion channel opening frequency

💡 How to Take adcloz 0.5mg tablet md

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of adcloz 0.5mg tablet md

✅ Common Side Effects

Drowsiness
dizziness
ataxia
fatigue
somnolence
coordination impairment

🚨 Serious Side Effects

Respiratory depression
paradoxical reactions (agitation, aggression)
dependence
withdrawal seizures
suicidal ideation

⚠️ Rare Side Effects

Blood dyscrasias (thrombocytopenia)
hepatic dysfunction
hypersensitivity reactions
SIADH

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Alcohol	Major	Increased sedation and risk of respiratory depression
Opioid analgesics	Major	Additive CNS depression, risk of respiratory depression
Cimetidine	Moderate	Increased clonazepam plasma concentration

🚨 Major Interactions

CNS depressants (e.g., alcohol, opioids, barbiturates)
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

CYP3A4 inducers (e.g., carbamazepine, phenytoin)
Valproate

ℹ️ Minor Interactions

Oral contraceptives
Cimetidine

🍽️ Food Interactions

Grapefruit juice may increase levels; avoid concurrent use.

🍷 Alcohol Interaction

Additive CNS depression; avoid alcohol.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to benzodiazepines, severe hepatic impairment, narrow-angle glaucoma, respiratory insufficiency, myasthenia gravis.

📊 Monitoring Parameters

Liver function tests, renal function, CBC, mental status, respiratory rate, signs of dependence/withdrawal.

🤱 Lactation Safety

Excreted in breast milk; avoid breastfeeding or use with caution.

💊 Overdose Management

Supportive care; flumazenil as antidote (use with caution due to risk of seizures).

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

🔗 View Profile

🔄 Substitutes for adcloz 0.5mg tablet md

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Alternative brands with exact same active ingredient (Clonazepam (0.5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.