aculanz 5mg tablet md - Olanzapine (5mg) medicine

aculanz 5mg tablet md - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Sanofi India Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is aculanz 5mg tablet md used for?

Anzip 2.5mg Tablet MD (Olanzapine) is used to treat NEURO CNS. It contains Olanzapine (5mg), which Antagonist at dopamine D2 and serotonin 5-HT2A receptors; also blocks 5-HT2C, 5-. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Olanzapine
  • Manufacturer: Sanofi India Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š aculanz 5mg tablet md Uses & Benefits

Schizophrenia, bipolar I disorder (acute manic/mixed episodes), maintenance treatment in bipolar disorder.

Off-label uses: Treatment-resistant depression (adjunct), Tourette's syndrome, autism-related irritability, anorexia nervosa.

๐Ÿ“‹ Drug Information

Generic Name(s)Olanzapine
Brand NameAnzip 2.5mg Tablet MD
ManufacturerSanofi India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassAtypical Antipsychotics
Route of AdministrationOral (tablet, orally disintegrating tablet).
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; food does not affect absorption.
DistributionExtensively distributed throughout the body; crosses blood-brain barrier.
Protein Binding93% bound to plasma proteins (albumin and alpha1-acid glycoprotein).
MetabolismHepatic metabolism via CYP1A2 and CYP2D6; major metabolite is N-desmethyl olanzapine.
Half-Life21-54 hours (mean 30 hours).
Excretion57% urine (7% unchanged), 30% feces.
Bioavailability60-80% (oral).
Onset of ActionWithin 1-2 hours for antipsychotic effect.
Peak Plasma Time5-8 hours.
Duration of Action24 hours.

How It Works

Antagonist at dopamine D2 and serotonin 5-HT2A receptors; also blocks 5-HT2C, 5-HT3, 5-HT6, alpha1-adrenergic, histamine H1, and muscarinic M1-M5 receptors.

Mechanism Steps

1Blocks dopamine D2 receptors in mesolimbic pathway, reducing positive symptoms of schizophrenia.
2Blocks serotonin 5-HT2A receptors in frontal cortex, improving negative symptoms and reducing extrapyramidal side effects.
3Blocks histamine H1 receptors, causing sedation and weight gain.

๐Ÿ’ก How to Take aculanz 5mg tablet md

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aculanz 5mg tablet md

โœ… Common Side Effects

  • Weight gain
  • Drowsiness
  • Dry mouth
  • Constipation
  • Increased appetite
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Neuroleptic malignant syndrome
  • Tardive dyskinesia
  • Hyperglycemia/diabetes
  • Seizures
  • QT prolongation
  • Pancreatitis

โš ๏ธ Rare Side Effects

  • Priapism
  • Rhabdomyolysis
  • Hepatitis
  • Agranulocytosis
  • Allergic reaction

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Fluvoxamine Major Increased olanzapine concentration; reduce dose.
Ciprofloxacin Major Increased olanzapine concentration; monitor.
Carbamazepine Major Decreased olanzapine concentration; may need dose increase.
Smoking Major Induces CYP1A2; decreased olanzapine concentration.
Diazepam Moderate Increased sedation.
Alcohol Moderate Increased CNS depression.
Levodopa Moderate Antagonism of levodopa effect.
Antihypertensives Moderate Additive hypotension.
Warfarin Minor Possible minor INR changes.
Lithium Minor No significant interaction.
Valproate Minor No significant interaction.

๐Ÿšจ Major Interactions

  • Fluvoxamine
  • Ciprofloxacin
  • Carbamazepine
  • Smoking

โšก Moderate Interactions

  • Diazepam
  • Alcohol
  • Levodopa
  • Antihypertensives

โ„น๏ธ Minor Interactions

  • Warfarin
  • Lithium
  • Valproate

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Increased CNS depression; avoid alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to olanzapine, narrow-angle glaucoma, severe CNS depression.

๐Ÿ“Š Monitoring Parameters

Blood glucose, lipid profile, weight, BMI, blood pressure, ECG (if risk factors), liver function tests.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; avoid breastfeeding or monitor infant.

๐Ÿ’Š Overdose Management

Supportive care; gastric lavage, activated charcoal; monitor vital signs, ECG; no specific antidote.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip if close to next dose; do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for aculanz 5mg tablet md

View All

Alternative brands with exact same active ingredient (Olanzapine (5mg)):

Medical Note: Always consult your doctor before switching medications.

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