Acucort 250mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (difficulty breathing, swelling of face or throat)
- Signs of skin infection (pus, increased pain, fever)
- Severe skin thinning or stretch marks
- Symptoms of adrenal suppression (fatigue, weakness, dizziness)
- Vision problems or eye pain if medicine gets into eyes
If experiencing severe symptoms, call emergency services immediately.
What is acucort 250mg injection used for?
This medicine is a topical corticosteroid used to treat inflammatory skin conditions like eczema and psoriasis. It works by reducing inflammation and itching. Apply a thin layer as directed by your doctor.
- Generic Name: Hydrocortisone
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acucort 250mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल कॉर्टिकोस्टेरॉयड है जिसका उपयोग त्वचा की सूजन, खुजली और लालिमा को कम करने के लिए किया जाता है। यह एक्जिमा, सोरायसिस, और संपर्क डर्मेटाइटिस जैसी स्थितियों के इलाज में मदद करती है। इसे डॉक्टर के निर्देशानुसार प्रभावित क्षेत्र पर पतली परत में लगाएं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर जलन, खुजली, सूखापन या लालिमा शामिल हो सकती है। लंबे समय तक उपयोग से त्वचा पतली हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन अगर आपको गंभीर एलर्जी या संक्रमण के लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर के बताए अनुसार ही करें। इसे आंखों, मुंह या अन्य श्लेष्मा झिल्ली के संपर्क में न आने दें। प्रभावित क्षेत्र को पट्टी से न ढकें जब तक डॉक्टर न कहें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।
💊 acucort 250mg injection Uses & Benefits
[{"condition":"Eczema","description":"Helps reduce inflammation, itching, and redness associated with eczema flares.","evidence":"Well-established"},{"condition":"Psoriasis","description":"Used to treat mild to moderate plaque psoriasis by reducing scaling and inflammation.","evidence":"Well-established"},{"condition":"Contact dermatitis","description":"Provides relief from inflammation and itching caused by allergic or irritant contact dermatitis.","evidence":"Well-established"},{"condition":"Seborrheic dermatitis","description":"Helps control inflammation and flaking in seborrheic dermatitis of the scalp and skin.","evidence":"Well-established"},{"condition":"Atopic dermatitis","description":"Reduces itching and inflammation in atopic dermatitis when used as part of a treatment plan.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Insect bite reactions","description":"Sometimes used to reduce local inflammation and itching from insect bites.","evidence":"Limited"},{"condition":"Lichen simplex chronicus","description":"May be used to break the itch-scratch cycle in localized areas.","evidence":"Limited"}]
Primary treatment for: Inflammatory skin conditions
Also treats: Eczema, Psoriasis, Contact dermatitis, Seborrheic dermatitis, Atopic dermatitis
📋 Drug Information
| Generic Name(s) | Hydrocortisone |
| Brand Name | Atonide-H Cream |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Glucocorticoids |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to glucocorticoid receptors in the cytoplasm of target cells. Once bound, the complex moves into the nucleus and alters gene transcription, leading to a decrease in the production of inflammatory mediators such as prostaglandins and leukotrienes, and a reduction in the activity of immune cells. This results in decreased inflammation, redness, itching, and swelling in the applied area.
Mechanism Steps
💡 How to Take acucort 250mg injection
Strength: Topical cream/ointment containing hydrocortisone 250 mg (strength as specified).
Dosage Information
| Adult Dosage | Apply a thin layer to the affected area once or twice daily as directed by your doctor. The frequency and duration of treatment depend on the condition being treated and your response to therapy. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use for longer than prescribed without medical supervision. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Use in children should be limited to the lowest effective dose for the shortest duration. |
| Elderly Dosage | Elderly patients may be more susceptible to systemic effects of corticosteroids. Use with caution and monitor for side effects. |
| Renal Impairment | No dosage adjustment is typically required for topical use in renal impairment. However, consult your doctor. |
| Hepatic Impairment | No dosage adjustment is typically required for topical use in hepatic impairment. However, consult your doctor. |
| Maximum Daily Dose | Not established from the available information. Follow your doctor's prescription. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acucort 250mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Ritonavir | Major | |
| Diuretics | Moderate | |
| Insulin | Moderate | |
| Metformin | Moderate |
🚨 Major Interactions
- Other topical corticosteroids
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
⚡ Moderate Interactions
- Diuretics
- Antidiabetic agents
🍷 Alcohol Interaction
No known direct interaction between alcohol and topically applied hydrocortisone. However, alcohol may worsen certain skin conditions and should be consumed in moderation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to hydrocortisone or any component of the formulation","Untreated bacterial, viral, or fungal skin infections","Acne vulgaris, rosacea, and perioral dermatitis","Use on the face, groin, or axillae unless directed by a doctor"]
⚠️ Warnings & Precautions
["For external use only. Avoid contact with eyes.","Do not use on open wounds or broken skin.","Do not cover with occlusive dressings unless directed.","Prolonged use may lead to systemic absorption and side effects.","Use in children may increase risk of systemic effects.","Consult doctor if condition worsens or does not improve."]
🤱 Lactation Safety
Topically applied hydrocortisone is generally considered safe during breastfeeding. Apply to the breast area only after feeding and wipe off before the next feed. Consult your doctor for guidance.
💊 Overdose Management
Topical overdose is unlikely. If excessive amounts are applied or ingested, seek medical attention. Symptoms of systemic overdose may include nausea, vomiting, and weakness. Treatment is supportive.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Use this medicine exactly as prescribed by your doctor. Apply a thin layer to the affected area and gently rub it in unless directed otherwise. Wash your hands before and after application, unless your hands are the treated area. Do not cover the treated area with bandages or dressings unless your doctor tells you to, as this can increase absorption and the risk of side effects. Avoid contact with your eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use this medicine on open wounds or broken skin. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for longer than the prescribed duration. If your condition does not improve or worsens after a few days, contact your doctor. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to systemic effects of corticosteroids due to thinner skin. Use the lowest effective dose for the shortest duration and monitor for side effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Topical corticosteroids are generally considered safe when used as directed, but prolonged use should be avoided.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine on surgical wounds. It should not be applied to open wounds or broken skin unless specifically directed.
🦷 Dental Procedures
No specific considerations for dental procedures. Inform your dentist about all medicines you are using.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions while using this medicine. However, avoid excessive sweating or friction on the treated area if it causes irritation.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or blurred vision, avoid these activities until you feel better.
🛑 When to Stop This Medicine
Stop using this medicine when your symptoms improve or as directed by your doctor. Do not stop abruptly if you have been using it for a long time without consulting your doctor, as this may cause a flare-up.
📅 Long-Term Use Effects
Prolonged use of topical corticosteroids can lead to skin thinning, stretch marks, and increased risk of systemic side effects such as adrenal suppression. Regular monitoring by a doctor is recommended if long-term use is necessary. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help soothe and protect the skin, complementing medical treatment.
Evidence: Well-establishedFor certain skin conditions, light therapy may be an option under medical supervision.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interaction between topical hydrocortisone and vaccines. However, if you are on other immunosuppressive therapies, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription in case you need to show it at customs. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue your regular application schedule as prescribed.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start noticing improvement within a few days, but full effects may take up to a week or more depending on the condition.
A: Only if your doctor has specifically prescribed it for facial use. The skin on the face is more sensitive and can absorb more medicine.
A: Apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
🤔 Common Patient Concerns
🔄 Substitutes for acucort 250mg injection
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure skin conditions permanently.
Fact: This medicine helps control symptoms but does not cure the underlying condition. - Myth: More medicine means faster results.
Fact: Using more than prescribed can increase side effects without improving results.
🔄 Alternative Options
Generic Alternatives
- Hydrocortisone topical
Brand Alternatives
- Acucort 250mg injection