actogod forte injection - Methylcobalamin (1500mcg) + Vitamin B6 (Pyridoxine) (100mg) medicine

actogod forte injection

4.5 (15 reviews)
๐Ÿญ Godase Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is actogod forte injection used for?

Alnacob Plus Injection (Methylcobalamin + Vitamin B6 (Pyridoxine)) is used to treat VITAMINS MINERALS NUTRIENTS. It contains Methylcobalamin (1500mcg) + Vitamin B6 (Pyridoxine) (100mg), which Methylcobalamin acts as a cofactor for methionine synthase, essential for myelin. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Methylcobalamin + Vitamin B6 (Pyridoxine)
  • Manufacturer: Godase Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š actogod forte injection Uses & Benefits

Peripheral neuropathy, megaloblastic anemia, homocysteinemia, vitamin B12 and B6 deficiency.

Off-label uses: Chronic fatigue syndrome, diabetic neuropathy, carpal tunnel syndrome.

๐Ÿ“‹ Drug Information

Generic Name(s)Methylcobalamin + Vitamin B6 (Pyridoxine)
Brand NameAlnacob Plus Injection
ManufacturerGodase Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassVitamins/Minerals/Nutrients
Route of AdministrationIntramuscular injection
StorageStore at 2-8ยฐC, protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntramuscular injection results in rapid absorption into systemic circulation.
DistributionDistributes widely in body tissues, including liver, kidneys, and nervous system.
Protein BindingMethylcobalamin: ~90% bound to transcobalamins; Pyridoxine: minimal protein binding.
MetabolismMethylcobalamin: converted to adenosylcobalamin and hydroxocobalamin; Pyridoxine: metabolized in liver to pyridoxal phosphate.
Half-LifeMethylcobalamin: ~6 days; Pyridoxine: 15-20 days.
ExcretionRenal excretion of metabolites; small amount in bile.
Bioavailability100% via intramuscular route.
Onset of ActionWithin 24-48 hours for neurological symptoms.
Peak Plasma TimeMethylcobalamin: 1-3 hours; Pyridoxine: 0.5-1 hour.
Duration of ActionSeveral days to weeks depending on dose and condition.

How It Works

Methylcobalamin acts as a cofactor for methionine synthase, essential for myelin synthesis; Pyridoxine is a cofactor for enzymes in neurotransmitter synthesis and homocysteine metabolism.

Mechanism Steps

1Methylcobalamin binds to intrinsic factor in GI tract (if oral) or directly enters circulation via IM injection.
2Methylcobalamin acts as cofactor for methionine synthase, converting homocysteine to methionine.
3Methionine is converted to S-adenosylmethionine (SAMe), essential for myelin synthesis.

๐Ÿ’ก How to Take actogod forte injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of actogod forte injection

โœ… Common Side Effects

  • Injection site pain
  • Mild diarrhea
  • Headache

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Peripheral neuropathy (with high dose pyridoxine)
  • Thrombotic events

โš ๏ธ Rare Side Effects

  • Acne
  • Photosensitivity
  • Hypersensitivity reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Levodopa Major Pyridoxine reduces levodopa efficacy by increasing peripheral metabolism.
Chloramphenicol Major May impair response to vitamin B12 therapy.
Colchicine Major May decrease absorption of vitamin B12.
Phenytoin Moderate Pyridoxine may decrease phenytoin levels.
Oral contraceptives Moderate May increase requirement for pyridoxine.
Isoniazid Moderate May cause pyridoxine deficiency.
Penicillamine Minor May increase pyridoxine requirement.
Cycloserine Minor May increase pyridoxine requirement.

๐Ÿšจ Major Interactions

  • Levodopa
  • Chloramphenicol
  • Colchicine

โšก Moderate Interactions

  • Anticonvulsants (phenytoin, phenobarbital)
  • Oral contraceptives
  • Isoniazid

โ„น๏ธ Minor Interactions

  • Penicillamine
  • Cycloserine

๐Ÿฝ๏ธ Food Interactions

None significant

๐Ÿท Alcohol Interaction

Chronic alcohol use may reduce absorption of vitamin B6.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component; severe renal impairment (for high doses of pyridoxine).

๐Ÿ“Š Monitoring Parameters

Serum vitamin B12 and B6 levels, homocysteine levels, neurological examination.

๐Ÿคฑ Lactation Safety

Safe; both vitamins are excreted in breast milk but not harmful.

๐Ÿ’Š Overdose Management

Discontinue injection; symptomatic treatment; pyridoxine overdose may cause neuropathy.

โฐ Missed Dose

Administer as soon as remembered; if close to next dose, skip missed dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

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