Articlar 125mg Dry Syrup (Cefaclor): Uses, Dosage, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe or persistent diarrhea, or blood in stool
- Severe skin rash with blistering or peeling
- Yellowing of the skin or eyes
- Decreased urine output or swelling in the legs
- Unusual bleeding or bruising
- High fever that does not improve after 48 hours of treatment
If experiencing severe symptoms, call emergency services immediately.
What is actaclor 125mg suspension used for?
This medicine is a cephalosporin antibiotic used to treat bacterial infections of the ear, throat, lungs, urinary tract, and skin. It works by killing bacteria and is available as a dry syrup for oral use.
- Generic Name: Cefaclor (125mg)
- Manufacturer: Custodian Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 actaclor 125mg suspension के बारे में (Hindi Summary)
उपयोग: यह दवा सेफाक्लोर नामक एंटीबायोटिक है, जिसका उपयोग बैक्टीरियल संक्रमणों जैसे कान, गले, फेफड़ों, मूत्र मार्ग और त्वचा के संक्रमण के इलाज के लिए किया जाता है। यह बैक्टीरिया को मारकर काम करती है और बच्चों के लिए ड्राई सिरप के रूप में उपलब्ध है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, गंभीर त्वचा प्रतिक्रियाएं और दस्त शामिल हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी एलर्जी, गुर्दे की बीमारी, पेट की समस्या, गर्भावस्था या स्तनपान के बारे में बताएं। दवा को डॉक्टर के बताए अनुसार ही लें, भोजन के साथ या बिना। पूरा कोर्स पूरा करें, चाहे आप बेहतर महसूस करें। खुराक छूट जाने पर याद आते ही लें, लेकिन अगली खुराक के करीब हो तो छोड़ दें। दोहरी खुराक न लें। तैयार सिरप को फ्रिज में रखें और 14 दिन बाद फेंक दें।
💊 actaclor 125mg suspension Uses & Benefits
- [{"condition":"Otitis media (middle ear infection)","description":"This medicine is effective against common bacteria causing ear infections, such as Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.","evidence":"Well-established"},{"condition":"Pharyngitis and tonsillitis","description":"Used to treat streptococcal throat infections when penicillin is not suitable.","evidence":"Well-established"},{"condition":"Lower respiratory tract infections","description":"Including bronchitis and pneumonia caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against susceptible strains of E.
- coli, Klebsiella, and Proteus.","evidence":"Well-established"},{"condition":"Skin and skin structure infections","description":"For uncomplicated skin infections caused by susceptible staphylococci and streptococci.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Dental infections","description":"Sometimes used as an alternative for dental abscesses when first-line antibiotics are not appropriate.","evidence":"Limited"},{"condition":"Lyme disease","description":"May be used in early localized Lyme disease, but not a first-line agent.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Otitis media, Pharyngitis, Tonsillitis, Bronchitis, Pneumonia, Urinary tract infections, Skin infections
📋 Drug Information
| Generic Name(s) | Cefaclor (125mg) |
| Brand Name | actaclor 125mg suspension |
| Manufacturer | Custodian Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 2nd generation |
| Route of Administration | Oral |
| Storage | Store the dry powder at room temperature (15-30°C) in a tightly closed container. After reconstitution, store the syrup in the refrigerator (2-8°C) and discard any unused portion after 14 days. Keep out of reach of children. |
| Shelf Life | The shelf life of the dry powder is typically 2 years from the date of manufacture. After reconstitution, the syrup should be used within 14 days if stored in the refrigerator. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefaclor is a bactericidal antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), which are enzymes involved in the cross-linking of peptidoglycan chains. This inhibition leads to a weakened cell wall and ultimately bacterial cell lysis and death. Cefaclor is active against a wide range of gram-positive and gram-negative bacteria, but it is susceptible to hydrolysis by some beta-lactamases.
Mechanism Steps
💡 How to Take actaclor 125mg suspension
Strength: Dry syrup containing Cefaclor 125mg per 5 mL after reconstitution.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 250 mg every 8 hours for most infections. For more severe infections or those caused by less susceptible organisms, the dose may be increased to 500 mg every 8 hours. The maximum recommended daily dose is 4 grams. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | The usual pediatric dose is 20 mg/kg/day divided into three doses for mild to moderate infections. For more severe infections, the dose may be increased to 40 mg/kg/day divided into three doses. The maximum daily dose should not exceed 1 gram. This medicine is not recommended for infants less than 1 month of age. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Elderly Dosage | Elderly patients may have decreased renal function, so dose adjustment may be necessary. The dose should be individualized based on renal function. No specific dose adjustments are recommended solely based on age, but caution is advised. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For creatinine clearance between 10-50 mL/min, the dose should be reduced to 50-100% of the usual dose. For creatinine clearance less than 10 mL/min, the dose should be reduced to 25-50% of the usual dose. Close monitoring is recommended. |
| Hepatic Impairment | No specific dose adjustment is required for hepatic impairment, as cefaclor is not significantly metabolized by the liver. However, caution is advised in patients with both hepatic and renal impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is 4 grams for adults and 1 gram for children. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of actaclor 125mg suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Loop diuretics | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Warfarin
- Probenecid
⚡ Moderate Interactions
- Oral contraceptives
- Loop diuretics (e.g., furosemide)
🍷 Alcohol Interaction
Alcohol does not directly interact with cefaclor, but it may worsen stomach upset and dizziness. It is advisable to avoid alcohol while taking this medicine, especially if you have an infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cefaclor or other cephalosporins","Previous anaphylactic reaction to penicillins (due to cross-reactivity)","Use in patients with a history of severe beta-lactam allergy"]
⚠️ Warnings & Precautions
["Before starting therapy, inquire about previous hypersensitivity reactions to cephalosporins, penicillins, or other drugs.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Prolonged use may result in overgrowth of non-susceptible organisms, including fungi.","If superinfection occurs, appropriate measures should be taken.","Cefaclor may cause a false-positive reaction for glucose in the urine with certain testing methods.","Do not use in patients with a history of gastrointestinal disease, particularly colitis.","Safety and efficacy in children under 1 month of age have not been established."]
🤱 Lactation Safety
Cefaclor is excreted in human breast milk in small amounts. It is generally considered safe during breastfeeding, but monitor the infant for diarrhea, thrush, or rash. Consult your doctor before use.
💊 Overdose Management
Symptoms of overdose may include nausea, vomiting, abdominal pain, and diarrhea. In case of overdose, discontinue the medicine and seek immediate medical attention. Treatment is symptomatic and supportive. Cefaclor is not significantly removed by hemodialysis or peritoneal dialysis.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you are allergic to cefaclor, other cephalosporins, or penicillins. Also, tell your doctor about any kidney disease, stomach or intestinal problems (especially colitis), or if you are pregnant or breastfeeding. Take this medicine exactly as prescribed, with or without food, but taking it with food may reduce stomach upset. Complete the full course even if you feel better. Do not share this medicine with others. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Do not double the dose. Store the reconstituted syrup in the refrigerator and discard any unused portion after 14 days. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced renal function and are more susceptible to antibiotic-associated diarrhea and other side effects. Dose adjustment may be necessary based on renal function. Monitor for signs of superinfection and ensure adequate hydration.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Cefaclor is generally considered safe in pregnancy (Category B), but use only if clearly needed. Discuss any concerns with your healthcare provider.
🏥 Post-Surgery Considerations
This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions regarding dosing and duration. Inform your surgeon if you have any allergies to antibiotics.
🦷 Dental Procedures
This medicine may be used to treat dental infections or as prophylaxis before dental procedures in certain patients. Inform your dentist if you are taking this medicine or have any antibiotic allergies.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid strenuous exercise or operating heavy machinery until you know how the medicine affects you. Otherwise, light to moderate exercise is generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some individuals. If affected, avoid driving or operating machinery. Otherwise, you can continue your normal daily activities as tolerated. Take the medicine at evenly spaced intervals as prescribed.
🛑 When to Stop This Medicine
Do not stop taking this medicine before completing the full prescribed course, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor before stopping. Your doctor will advise if and when to stop.
📅 Long-Term Use Effects
Long-term use of this medicine is not typically recommended unless for a specific chronic infection under medical supervision. Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi, and may increase the risk of antibiotic resistance. Regular monitoring of renal and hepatic function may be advised for extended therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhea when taken alongside this medicine.
Evidence: ModerateFor symptom relief while the antibiotic takes effect.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled to receive a live bacterial vaccine (e.g., typhoid vaccine), antibiotics may reduce its effectiveness. Consult your doctor for timing.
📦 Storage Guide
✅ DO
Store the dry powder at room temperature (15-30°C)
❌ DON'T
Do not refrigerate the dry powder
✅ DO
After reconstitution, store in the refrigerator (2-8°C)
❌ DON'T
Do not leave reconstituted syrup at room temperature for long periods
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. If traveling with the reconstituted syrup, keep it refrigerated using a cool pack. For air travel, carry it in your hand luggage to avoid temperature extremes. Check customs regulations for carrying antibiotics in your destination country. If crossing time zones, adjust dosing times gradually, but maintain the prescribed interval between doses. Consult your doctor or pharmacist for specific advice.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 1-2 days, but it may take 3-5 days for significant improvement. Complete the full course as prescribed.
A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Yes, this medicine is commonly prescribed for children. The dose is based on the child's weight and must be determined by a doctor.
A: No, you must complete the full prescribed course to ensure the infection is fully treated and to prevent antibiotic resistance.
🤔 Common Patient Concerns
🔄 Substitutes for actaclor 125mg suspension
View AllAlternative brands with exact same active ingredient:
-
colors syrupMefro Pharmaceuticals Pvt Ltd ₹16.00 87.2% CHEAPER
-
eclor 125mg premix syrupLupin Ltd ₹57.19 54.2% CHEAPER
-
zenclor 125mg suspensionMankind Pharma Ltd ₹59.00 52.8% CHEAPER
-
duclor kid 125mg tabletMorepen Laboratories Ltd ₹64.20 48.6% CHEAPER
-
Sayochlor 125mg Dry SyrupZota Health care Ltd ₹64.90 48.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections. It does not treat viral infections. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full prescribed course to prevent bacterial resistance and ensure the infection is fully treated. - Myth: Antibiotics weaken the immune system.
Fact: Antibiotics do not weaken the immune system; they target bacteria. However, they can disrupt normal gut flora, which may have temporary effects.
🔄 Alternative Options
Generic Alternatives
- Cefaclor 125mg/5mL dry syrup (various manufacturers)
Brand Alternatives
- Articlar 125mg Dry Syrup