aconex sp 100mg/325mg/15mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
aconex sp 100mg/325mg/15mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Nexkem Pharmaceuticals Pvt Ltd. Contains Aceclofenac (100mg) + Paracetamol (325mg).

aconex sp 100mg/325mg/15mg tablet - Uses, Price, Side Effects & Substitutes

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🏭 Nexkem Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is aconex sp 100mg/325mg/15mg tablet used for?

Aldigesic P (Aceclofenac + Paracetamol) is used to treat Pain and inflammation in osteoarthritis. It contains Aceclofenac (100mg) + Paracetamol (325mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paraceta. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac + Paracetamol
  • Manufacturer: Nexkem Pharmaceuticals Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 aconex sp 100mg/325mg/15mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

aconex sp 100mg/325mg/15mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aceclofenac (100mg) + Paracetamol (325mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Aceclofenac + Paracetamol
Brand NameAldigesic P
ManufacturerNexkem Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in tissues
Protein BindingAceclofenac: >99%; Paracetamol: 10-25%
MetabolismAceclofenac: hepatic via CYP2C9; Paracetamol: hepatic via glucuronidation and sulfation
Half-LifeAceclofenac: 4-5 h; Paracetamol: 2-3 h
ExcretionRenal (primarily urine)
BioavailabilityAceclofenac: ~100%; Paracetamol: ~88%
Onset of Action30-60 minutes
Peak Plasma TimeAceclofenac: 1-3 h; Paracetamol: 0.5-2 h
Duration of Action4-6 hours

Pharmacodynamics

Mechanism of ActionAceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
Target ReceptorCyclooxygenase (COX) enzymes
Pharmacodynamic EffectsAnalgesic, anti-inflammatory, antipyretic

💡 How and when to take aconex sp 100mg/325mg/15mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture.

⚙️ How aconex sp 100mg/325mg/15mg tablet Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.

1 Aceclofenac inhibits COX-1 and COX-2, decreasing prostaglandin synthesis.
⬇️
2 Reduced prostaglandins lead to decreased inflammation and pain.
⬇️
3 Paracetamol inhibits COX in the CNS, reducing pain signal transmission.
⬇️
4 Paracetamol acts on hypothalamic heat-regulating center to reduce fever.
⬇️
5 Combined effect provides enhanced analgesia and antipyresis.

💊 aconex sp 100mg/325mg/15mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.

Off-label uses: Postoperative pain, migraine (limited evidence).

⚠️ What are the side effects of aconex sp 100mg/325mg/15mg tablet?

✅ Common Side Effects

  • Nausea
  • Dizziness
  • Drowsiness
  • Rash
  • GI upset

🚨 Serious Side Effects

  • GI bleeding
  • Hepatotoxicity
  • Renal failure
  • Stevens-Johnson syndrome

⚠️ Rare Side Effects

  • Blood dyscrasias
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for aconex sp 100mg/325mg/15mg tablet

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Alternative medicines with exact same composition and strength (Aceclofenac (100mg) + Paracetamol (325mg)):

  1. rumatab sp 100 mg/325 mg/15 mg tablet
    Simpson Brawn Pharmaceuticals₹5.23💰 93.8% CHEAPER
  2. aclopen plus 100mg/325mg tablet
    Morepen Laboratories Ltd₹6.44💰 92.4% CHEAPER
  3. dolospark 100mg/325mg tablet
    Spark Medicare Pvt Ltd₹7.31💰 91.3% CHEAPER
  4. aceforce mr 100 mg/325 mg/250 mg tablet
    Shreya Life Sciences Pvt Ltd₹10.55💰 87.5% CHEAPER
  5. asozen-plus tablet
    Zeelab Pharmacy Pvt Ltd₹11.00💰 87% CHEAPER
  6. acefex p 100mg/325mg tablet
    Zydus Cadila₹11.25💰 86.7% CHEAPER
  7. afecox 100 mg/325 mg tablet
    Apostle Remedies₹12.19💰 85.6% CHEAPER
  8. aceclofast tablet
    Wings Biotech Ltd₹12.90💰 84.7% CHEAPER
  9. dolospark-sp tablet
    Spark Medicare Pvt Ltd₹13.13💰 84.4% CHEAPER
  10. nicoace mr tablet
    Abbott₹15.00💰 82.2% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Lithium Major Increased lithium levels
Aspirin Major Increased risk of GI ulceration
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic efficacy
Anticoagulants Moderate Increased INR
SSRIs Moderate Increased bleeding risk
Antacids Minor Reduced absorption of aceclofenac
Cholestyramine Minor Reduced absorption of paracetamol

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • SSRIs

ℹ️ Minor Interactions

  • Antacids
  • Cholestyramine

🍽️ Food Interactions

Food may delay absorption; avoid alcohol.

🍷 Alcohol Interaction

Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.

📊 Monitoring Parameters

Liver function tests, renal function, CBC, blood pressure.

🤱 Lactation Safety

Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.

💊 Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

🛑 Myths vs. Facts about aconex sp 100mg/325mg/15mg tablet

  • Myth: Generic substitutes of aconex sp 100mg/325mg/15mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Aceclofenac (100mg) + Paracetamol (325mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of aconex sp 100mg/325mg/15mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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Intermittent Fasting (IF) is not just a diet trend; it is a scientifically-backed lifestyle pattern that aligns beautifully with our ancient Indian traditions of 'Upvaas' (fasting). As your doctor, I want to guide you through a practical, safe, and effective approach to IF, tailored specifically for the Indian palate and daily routine. Let's understand how to do it right, without compromising your health or energy. Why Intermittent Fasting Works for Indians Our modern Indian lifestyle, with its high-carb meals (rice, roti, sweets) and long sitting hours, often leads to insulin resistance, weight gain, and metabolic syndrome. IF works by giving your digestive system a break, allowing your body to switch from burning sugar (glucose) to burning stored fat for energy. This is called metabolic switching. It helps in: Weight Loss: Reduces calorie intake naturally and boosts fat burning. Better Blood Sugar Control: Improves insulin sensitivity, crucial for prediabetes and type 2 diabetes management. Reduced Inflammation: Helps with joint pain, skin issues, and chronic diseases. Improved Gut Health: Gives your gut time to repair and reduces bloating. Best Intermittent Fasting Timings for Indians Choose a schedule that fits your daily routine. The 16:8 method is the most practical and sustainable for Indians. You fast for 16 hours and eat within an 8-hour window. Option 1 (Early Dinner): Finish your last meal by 7 PM. Then skip breakfast (or have a late breakfast) and eat your first meal at 11 AM. This is ideal for those who eat dinner early. Option 2 (Late Breakfast): Start your eating window at 12 PM (noon) and finish by 8 PM. This works well for those who have lunch as their main meal. Important Warning: Do NOT skip lunch or dinner. Lunch is the most important meal for most Indians. Never go more than 16 hours of fasting without medical supervision if you have diabetes or are on medication. Your Daily Routine: A Practical Guide Here is a sample daily routine for a 16:8 fast (eating window: 12 PM to 8 PM): Morning (6 AM - 12 PM) - Fasting State: Drink plenty of water, black tea, or green tea. You can have lemon water or coconut water (in small amounts) if you feel weak. Avoid milk, sugar, or any solid food. Light exercise like yoga or a brisk walk is excellent during this time. 12 PM - Break Fast (Lunch): Start with a balanced meal: Vegetable sabzi, one roti or small portion of brown rice, dal, and a bowl of salad. Include healthy fats like ghee or avocado. This meal should be your largest. 4 PM - Snack: A handful of nuts (badam, akhrot), a bowl of fresh fruit, or a small cup of sprouts. 7:30 PM - Dinner: Keep it light. Grilled paneer, vegetable soup, or a small bowl of khichdi. Finish your meal by 8 PM sharp. 8 PM - 12 PM (Next Day) - Fasting State: Only water or herbal tea. No late-night snacking. Actionable Diet & Home Remedies Hydrate Smartly: Drink 8-10 glasses of water during your fasting window. Add a pinch of Himalayan pink salt or jeera water to maintain electrolytes. Eat Protein First: In your eating window, always start with protein (dal, paneer, eggs, chicken) to keep you full longer and stabilize blood sugar. Include Ghee: A teaspoon of desi ghee in your dal or roti is excellent for satiety and fat-soluble vitamins. Avoid 'Fake' Fasting: No fruit juices, packaged snacks, or sugary chai during fasting. These break your fast and spike insulin. Listen to Your Body: If you feel dizzy, extremely hungry, or have a headache, break your fast immediately with a small meal. IF should never feel like punishment. When to See a Doctor Intermittent fasting is not for everyone. Do NOT start IF without consulting your doctor if you: Have Type 1 diabetes or are on insulin or sulfonylureas for Type 2 diabetes. Are pregnant, breastfeeding, or trying to conceive. Have a history of eating disorders (anorexia, bulimia). Are underweight (BMI less than 18.5) or malnourished. Take medications for blood pressure, heart disease, or kidney issues. Experience severe acidity, gallstones, or chronic fatigue. Remember, dear reader, intermittent fasting is a tool, not a miracle cure. It works best when combined with a nutrient-rich Indian diet, regular physical activity, and good sleep. Start slowly, be consistent, and always prioritize your health over the clock. Your body is your temple—treat it with respect.

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