Acolef 750mg Tablet - Uses, Price, Side Effects
What is acolef 750mg tablet used for?
Acolef 750mg Tablet contains Levofloxacin, a fluoroquinolone antibiotic that treats bacterial infections by stopping bacteria from multiplying. It is used for respiratory, urinary tract, skin, and eye infections. Take as prescribed, usually once or twice daily. Common side effects include nausea, diarrhea, and headache.
- Generic Name: Levofloxacin
- Manufacturer: Accosts Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ acolef 750mg tablet Uses & Benefits
Acute bacterial sinusitis, acute exacerbation of chronic bronchitis, community-acquired pneumonia, complicated urinary tract infections, acute pyelonephritis, chronic bacterial prostatitis, skin and soft tissue infections.
Off-label uses: Tuberculosis, Anthrax, Plague, Legionnaires' disease
๐ Drug Information
| Generic Name(s) | Levofloxacin |
| Brand Name | Alevo 500 Tablet |
| Manufacturer | Accosts Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Quinolones/ Fluroquinolones |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.
Mechanism Steps
๐ก How to Take acolef 750mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of acolef 750mg tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Insomnia
๐จ Serious Side Effects
- Tendon rupture
- Peripheral neuropathy
- QT prolongation
- Seizures
- Clostridium difficile-associated diarrhea
โ ๏ธ Rare Side Effects
- Anaphylaxis
- Stevens-Johnson syndrome
- Hepatotoxicity
- Renal failure
- Blood dyscrasias
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| NSAIDs | Moderate | Increased CNS stimulation risk |
| Antacids | Moderate | Reduced absorption of levofloxacin |
๐จ Major Interactions
- Warfarin
- Antidiabetic agents
- NSAIDs
- Corticosteroids
- QT-prolonging agents
โก Moderate Interactions
- Theophylline
- Cyclosporine
- Probenecid
- Cimetidine
โน๏ธ Minor Interactions
- Calcium
- Iron
- Zinc
- Sucralfate
๐ฝ๏ธ Food Interactions
Avoid dairy products, calcium-fortified juices, and antacids containing magnesium or aluminum within 2 hours of dosing.
๐ท Alcohol Interaction
No direct interaction, but may increase CNS side effects like dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to levofloxacin or other quinolones; history of tendon disorders with quinolones; myasthenia gravis; epilepsy; children and adolescents (<18 years).
๐ Monitoring Parameters
Renal function, blood glucose, signs of tendonitis or tendon rupture, CNS effects, QT interval.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Supportive care; monitor ECG for QT prolongation; hemodialysis not effective.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for acolef 750mg tablet
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Medical Note: Always consult your doctor before switching medications.