acodac 20 capsule - Fluoxetine (20mg) medicine

Acodac 20 Capsule - Uses, Price, Side Effects, Dosage & Interactions

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๐Ÿญ Accosts Remedies Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is acodac 20 capsule used for?

Acodac 20 Capsule contains Fluoxetine 20mg, a selective serotonin reuptake inhibitor (SSRI) used to treat depression, obsessive-compulsive disorder (OCD), and anxiety. It works by increasing serotonin levels in the brain, improving mood and reducing symptoms. Take as prescribed, usually once daily in the morning.

  • Generic Name: Fluoxetine
  • Manufacturer: Accosts Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š acodac 20 capsule Uses & Benefits

Major depressive disorder, obsessive-compulsive disorder, bulimia nervosa, panic disorder, premenstrual dysphoric disorder.

Off-label uses: Premature ejaculation, social anxiety disorder, post-traumatic stress disorder, fibromyalgia.

๐Ÿ“‹ Drug Information

Generic Name(s)Fluoxetine
Brand NameAcodac 20 Capsule
ManufacturerAccosts Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSelective Seretonin Reuptake inhibitors (SSRIs)
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; food does not affect absorption.
DistributionWidely distributed; crosses the blood-brain barrier and placenta.
Protein BindingApproximately 94.5% bound to plasma proteins (albumin and alpha-1-acid glycoprotein).
MetabolismHepatic metabolism via CYP2D6, CYP2C9, and CYP3A4 to active metabolite norfluoxetine.
Half-LifeFluoxetine: 4-6 days; Norfluoxetine: 4-16 days.
ExcretionPrimarily renal (80% as metabolites, 10% as unchanged drug); fecal (15%).
BioavailabilityApproximately 72% (oral).
Onset of Action1-2 weeks for antidepressant effect; may take 4-6 weeks for full effect.
Peak Plasma Time6-8 hours.
Duration of ActionLong-acting due to long half-life; steady state achieved in 2-4 weeks.

How It Works

Selectively inhibits serotonin reuptake in the presynaptic neuron, increasing serotonin levels in the synaptic cleft.

Mechanism Steps

1Fluoxetine binds to the serotonin transporter (SERT) on presynaptic neurons.
2Inhibits reuptake of serotonin from the synaptic cleft into the presynaptic neuron.
3Increases extracellular serotonin concentration in the synaptic cleft.

๐Ÿ’ก How to Take acodac 20 capsule

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of acodac 20 capsule

โœ… Common Side Effects

  • Nausea
  • Insomnia
  • Headache
  • Nervousness
  • Diarrhea
  • Dry mouth
  • Sweating
  • Sexual dysfunction

๐Ÿšจ Serious Side Effects

  • Serotonin syndrome
  • Suicidal thoughts/behavior
  • QT prolongation
  • Seizures
  • Hyponatremia
  • Bleeding abnormalities

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Angioedema
  • Hepatotoxicity
  • Pancreatitis
  • Galactorrhea

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Risk of serotonin syndrome (hyperthermia, rigidity, autonomic instability)
Pimozide Major QT prolongation
Thioridazine Major QT prolongation
Warfarin Moderate Increased INR and bleeding risk
NSAIDs Moderate Increased bleeding risk
Triptans Moderate Additive serotonergic effects, risk of serotonin syndrome

๐Ÿšจ Major Interactions

  • MAOIs
  • Pimozide
  • Thioridazine
  • Linezolid
  • Methylene Blue

โšก Moderate Interactions

  • Warfarin
  • NSAIDs
  • Aspirin
  • CYP2D6 substrates (e.g., TCAs, antipsychotics)
  • Serotonergic drugs (e.g., triptans, tramadol, St. John's Wort)

โ„น๏ธ Minor Interactions

  • CYP2D6 inhibitors (e.g., quinidine)
  • CYP3A4 inducers (e.g., carbamazepine)

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; grapefruit juice may increase levels slightly.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS depression and hepatotoxicity risk.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to fluoxetine; concurrent use with MAOIs or within 14 days of MAOI discontinuation; concurrent pimozide or thioridazine.

๐Ÿ“Š Monitoring Parameters

Suicidal ideation, serotonin syndrome symptoms, liver function tests, renal function, ECG in elderly or cardiac patients.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised. Consider risk-benefit.

๐Ÿ’Š Overdose Management

Activated charcoal, supportive care; monitor ECG, vital signs; no specific antidote; consider benzodiazepines for seizures.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for acodac 20 capsule

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Alternative brands with exact same active ingredient (Fluoxetine (20mg)):

Medical Note: Always consult your doctor before switching medications.

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