Acamprosate 333 mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe diarrhoea leading to dehydration
- Chest pain or palpitations
- Reduced urine output or swelling in the legs
- Thoughts of harming yourself or others
- Severe skin rash or blistering
- Yellowing of the skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is acmanet 333mg tablet used for?
This medicine contains Acamprosate 333 mg, an anti-craving agent used to help people with alcohol dependence stay abstinent. It works by balancing brain chemicals and is most effective when combined with counselling.
- Generic Name: Acamprosate (333mg)
- Manufacturer: Shatayushi Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acmanet 333mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा अल्कोहल (शराब) की लत से जूझ रहे लोगों की मदद करने के लिए इस्तेमाल की जाती है। यह शराब छोड़ने के बाद दोबारा शराब पीने की इच्छा को कम करने में मदद करती है। यह दवा सबसे अच्छा तब काम करती है जब इसे काउंसलिंग और सहायता कार्यक्रम के साथ लिया जाए। यह दवा शराब की लत का इलाज नहीं है, बल्कि शराब छोड़ने में मदद करने वाली दवा है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द, सिरदर्द, नींद न आना, बेचैनी और खुजली शामिल हो सकते हैं। ये आमतौर पर हल्के होते हैं और कुछ हफ्तों में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, या दिल की धड़कन में बदलाव महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बदलें और न ही अचानक बंद करें। इस दवा के साथ शराब बिल्कुल न पिएं। अगर आपको किडनी या लीवर की समस्या है, या आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को जरूर बताएं। नियमित रूप से डॉक्टर से मिलते रहें ताकि वे आपकी प्रगति की निगरानी कर सकें।
💊 acmanet 333mg tablet Uses & Benefits
- [{"condition":"Alcohol dependence (maintenance of abstinence)","description":"This medicine helps people with alcohol dependence remain abstinent after they have stopped drinking.
- It reduces craving and helps prevent relapse when used alongside counselling and psychosocial support.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Other substance use disorders","description":"There is limited research on the use of this medicine for other addictive disorders, and it is not approved for these purposes.","evidence":"Limited"}]
Primary treatment for: Alcohol dependence
📋 Drug Information
| Generic Name(s) | Acamprosate (333mg) |
| Brand Name | acmanet 333mg tablet |
| Manufacturer | Shatayushi Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Alcohol deaddiction |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | Not established from the available information. Refer to the packaging for the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Acamprosate is thought to restore the normal balance between excitatory and inhibitory neurotransmission in the brain, which is disrupted by chronic alcohol use. It appears to modulate glutamate activity and enhance GABAergic inhibition, helping to reduce the craving and negative emotional states that can lead to relapse.
Mechanism Steps
💡 How to Take acmanet 333mg tablet
Strength: Acamprosate 333 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 666 mg (two 333 mg tablets) taken three times daily. For patients with moderate kidney impairment, a lower dose may be prescribed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's instructions exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced kidney function, so the dose may need adjustment. Your doctor will determine the appropriate dose based on your kidney function and overall health. |
| Renal Impairment | In patients with moderate kidney impairment (eGFR 30-50 mL/min/1.73 m2), a reduced dose of 333 mg three times daily may be used. This medicine is contraindicated in severe kidney impairment (eGFR less than 30 mL/min/1.73 m2). |
| Hepatic Impairment | No specific dose adjustment is required for mild to moderate liver impairment, as Acamprosate is not significantly metabolised by the liver. However, consult your doctor for personalised advice. |
| Maximum Daily Dose | The maximum recommended daily dose is 1998 mg (six 333 mg tablets) in patients with normal kidney function. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acmanet 333mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe kidney impairment (eGFR less than 30 mL/min/1.73 m2)","Known hypersensitivity to Acamprosate or any component of the tablet","Children and adolescents under 18 years of age"]
⚠️ Warnings & Precautions
["This medicine should be used as part of a comprehensive treatment programme that includes counselling and psychosocial support.","Do not stop taking this medicine abruptly without consulting your doctor.","Use with caution in patients with moderate kidney impairment; dose adjustment may be required.","Patients with a history of depression or suicidal thoughts should be monitored closely.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid alcohol completely while taking this medicine."]
🤱 Lactation Safety
It is not known whether Acamprosate passes into breast milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
If you suspect an overdose, seek immediate medical attention. Overdose symptoms may include severe diarrhoea, nausea, vomiting, and electrolyte imbalances. Treatment is supportive and symptomatic. Contact your local poison control centre or emergency department right away.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice, because stopping suddenly may increase the risk of relapse. This medicine works best when combined with counselling and lifestyle changes. Avoid alcohol completely while taking this medicine, as drinking can reduce its benefits and increase the risk of side effects. Inform your doctor if you have kidney or liver problems, heart disease, or if you are pregnant, planning pregnancy, or breastfeeding. Keep all follow-up appointments so your doctor can monitor your progress and adjust treatment if needed. Store this medicine in its original container at room temperature, away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function, so the dose may need adjustment. Regular monitoring of kidney function is recommended. Falls and confusion should be monitored, though these are uncommon with this medicine.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before continuing this medicine. The safety of Acamprosate during pregnancy is not well established. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
Inform your surgeon and anaesthesiologist that you are taking this medicine before any surgery. It is generally safe to continue, but your healthcare team should be aware.
🦷 Dental Procedures
This medicine does not usually interfere with dental procedures. However, inform your dentist about all medicines you are taking. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine does not usually affect your ability to exercise. However, if you feel dizzy or unwell, avoid strenuous activity until you feel better. Consult your doctor before starting any new exercise programme.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to impair your ability to drive or operate machinery. However, if you experience dizziness, drowsiness, or vision changes, avoid these activities until you feel normal. It is important to continue your treatment while maintaining your work and daily routines.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will decide when it is appropriate to stop based on your progress and risk of relapse. Stopping suddenly may increase the risk of returning to alcohol use.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well tolerated. Regular monitoring of kidney function is advised, especially in patients with underlying kidney disease. The duration of treatment is usually determined by your doctor based on your progress and risk of relapse. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps identify and change thought patterns and behaviours related to alcohol use.
Evidence: Well-establishedPeer support can provide encouragement and accountability during recovery.
Evidence: Well-establishedAnother anti-craving medicine that may be used as an alternative or in combination.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your hand luggage to avoid loss or exposure to extreme temperatures. If you are crossing time zones, try to maintain the same dosing schedule as closely as possible, but do not double up on doses. Store it at room temperature and away from direct sunlight. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The benefits of this medicine develop gradually over days to weeks of consistent use. It is important to take it regularly as prescribed.
A: No, you should not stop taking this medicine without consulting your doctor. Stopping suddenly may increase the risk of relapse.
A: Acamprosate has few known interactions, but always inform your doctor about all medicines you are taking.
🤔 Common Patient Concerns
🔄 Substitutes for acmanet 333mg tablet
View AllAlternative brands with exact same active ingredient:
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acmacal 333mg tabletPsycormedies ₹93.01 12.3% CHEAPER
-
duacam 333mg tabletRyon Pharma ₹93.75 11.6% CHEAPER
-
sanprol 333mg tabletSanity Pharma ₹99.75 5.9% CHEAPER
-
camprosys 333mg tabletNeosys Medicare ₹101.25 4.5% CHEAPER
-
loycium 333mg tabletEnrico Pharmaceuticals ₹109.45 3.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Acamprosate is a cure for alcoholism.
Fact: Acamprosate helps maintain abstinence but is not a cure. It works best with counselling and lifestyle changes. - Myth: You can drink alcohol while taking Acamprosate.
Fact: Alcohol should be avoided completely while taking this medicine, as it reduces effectiveness and increases risks. - Myth: Acamprosate causes immediate effects.
Fact: The benefits develop gradually over days to weeks of consistent use.
🔄 Alternative Options
Generic Alternatives
- Acamprosate 333 mg tablet