Acecloflam P Syrup: Complete Guide to Uses, Dosage, and Safety
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is aclosec oral suspension used for?
This medicine is a combination syrup of aceclofenac and paracetamol used for short-term relief of pain, inflammation, and fever. It is taken orally with food, usually 10 ml two to three times daily as prescribed by a doctor.
- Generic Name: Aceclofenac (50mg/5ml) + Paracetamol (125mg/5ml)
- Manufacturer: Adison Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aclosec oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटामिनोफेन और एसिटोक्लोफेनाक का संयोजन है, जिसका उपयोग दर्द, सूजन और बुखार से राहत के लिए किया जाता है। यह मांसपेशियों के दर्द, दांत दर्द, सर्जरी के बाद के दर्द और बुखार में प्रभावी है। इसे भोजन के साथ लेना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, एलर्जी, यकृत और गुर्दे की समस्या शामिल हो सकती है।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। इसे भोजन के साथ लें। शराब का सेवन न करें। यदि आपको पेट अल्सर, गुर्दे या यकृत की बीमारी है तो डॉक्टर को बताएं। बिना सलाह के अन्य दर्द निवारक दवाएं न लें।
💊 aclosec oral suspension Uses & Benefits
[{"condition":"Musculoskeletal pain and inflammation","description":"Relieves pain and reduces swelling in conditions such as sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgical procedures.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever due to the paracetamol component.","evidence":"Well-established"},{"condition":"Osteoarthritis and rheumatoid arthritis","description":"May be used for symptomatic relief of pain and stiffness in these chronic conditions, though syrup form is less common for long-term use.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but other NSAIDs are preferred.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation
Also treats: Fever, Musculoskeletal injuries, Dental pain, Post-operative pain
📋 Drug Information
| Generic Name(s) | Aceclofenac (50mg/5ml) + Paracetamol (125mg/5ml) |
| Brand Name | aclosec oral suspension |
| Manufacturer | Adison Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac, an NSAID, inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system, where it inhibits prostaglandin synthesis and may also modulate pain perception through other pathways. Together, they provide both peripheral anti-inflammatory and central analgesic/antipyretic effects.
Mechanism Steps
💡 How to Take aclosec oral suspension
Strength: Each 5 ml contains Aceclofenac 50 mg and Paracetamol 125 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 ml (2 teaspoons) two to three times daily, or as prescribed by your doctor. The dose may vary based on the indication, severity of pain, and individual response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially gastrointestinal and renal side effects. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Consult your doctor for appropriate dosing. Not recommended in severe renal impairment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid in severe hepatic impairment. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum daily dose should not exceed 30 ml (6 teaspoons) in 24 hours, or as prescribed by your doctor. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aclosec oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Lithium | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, aspirin)
- Methotrexate
- ACE inhibitors and ARBs
- Diuretics
⚡ Moderate Interactions
- Corticosteroids
- SSRIs
- Lithium
- Antihypertensives (beta-blockers, etc.)
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and liver damage, especially due to the paracetamol component. It can also enhance the sedative effects of the medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to aceclofenac, paracetamol, or other NSAIDs","Active peptic ulcer or history of recurrent peptic ulcer","Gastrointestinal bleeding or perforation","Severe heart failure","Severe hepatic impairment","Severe renal impairment","Third trimester of pregnancy","Children under 12 years (unless specifically prescribed by a pediatrician)"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose or duration.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of asthma, especially aspirin-sensitive asthma.","Do not use concurrently with other NSAIDs or paracetamol-containing products.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Consult your doctor if symptoms persist beyond 7 days."]
🤱 Lactation Safety
Aceclofenac and paracetamol are excreted in breast milk in small amounts. Paracetamol is generally considered safe during breastfeeding. Aceclofenac should be used with caution. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to paracetamol and gastrointestinal bleeding due to aceclofenac. Symptoms of overdose may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment includes activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and gastrointestinal bleeding. Do not use this medicine for more than a few days without consulting a doctor. If you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma, inform your doctor before taking this medicine. Do not take other medicines containing paracetamol or NSAIDs while on this medicine without medical advice. Keep out of reach of children. Store at room temperature away from direct sunlight and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly. Avoid concurrent use with other NSAIDs.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. NSAIDs like aceclofenac are generally avoided in the third trimester. Paracetamol is considered relatively safe when used as directed. Discuss alternative pain relief options with your doctor.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain relief as prescribed by your surgeon. Inform your surgeon about all medicines you are taking. It may increase bleeding risk, so use with caution after surgery. Follow your surgeon's instructions regarding dosing and duration.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may increase bleeding risk during dental surgery. Your dentist may advise you to stop it temporarily or adjust the dose. Do not stop without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you have musculoskeletal pain. Gentle stretching and low-impact activities are generally safe. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Generally, it does not significantly interfere with daily activities if taken as prescribed.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if you experience severe side effects, or if you develop signs of gastrointestinal bleeding, liver problems, or allergic reactions. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver damage, and cardiovascular events. Regular monitoring of liver and kidney function is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor if you need to use it for more than 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedMay help reduce localized pain and inflammation.
Evidence: LimitedSome evidence for pain relief in certain conditions.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination. There is no need to postpone vaccination solely due to this medicine unless advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines. Keep it in your carry-on luggage if flying.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: It is best taken with food or milk to reduce the risk of stomach upset.
A: Pediatric dosing is not established. Consult a pediatrician for appropriate use in children.
A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for aclosec oral suspension
View AllAlternative brands with exact same active ingredient:
-
movexx plus syrupCipla Ltd ₹14.22 68.4% CHEAPER
-
acezof-plus oral suspensionBioshine Healthcare Pvt Ltd ₹27.00 40% CHEAPER
-
aloo 50mg/5ml/125mg/5ml syrupBestoChem Formulations India Ltd ₹29.00 35.6% CHEAPER
-
afib p 50mg/125mg oral suspensionSamco Pharma Works Pvt Ltd ₹35.00 22.2% CHEAPER
-
vriace p oral suspensionGopal Lifesciences ₹36.00 20% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach upset. - Myth: It is safe to take more than the recommended dose for faster relief.
Fact: Exceeding the dose can cause serious liver and stomach problems. - Myth: This medicine can be used for long-term pain management without doctor supervision.
Fact: Long-term use requires medical supervision due to risks of kidney, liver, and heart problems.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac + Paracetamol syrup
Brand Alternatives
- Acecloflam P Syrup