Acnac-MR Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is aclocare-plus oral suspension used for?
This medicine is a combination of Aceclofenac and Paracetamol used for short-term relief of pain and inflammation in conditions like arthritis, dental pain, and musculoskeletal injuries. It works by reducing prostaglandins that cause pain and swelling. Take it with food to avoid stomach upset and do not exceed the prescribed dose.
- Generic Name: Aceclofenac (100mg) + Paracetamol (250mg)
- Manufacturer: Carezone Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aclocare-plus oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटोक्लोफेनाक और पैरासिटामोल का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है। यह गठिया, दांत दर्द, मांसपेशियों में दर्द, और सर्जरी के बाद के दर्द में राहत देती है। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत की क्षति, और एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, सांस लेने में कठिनाई, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को भोजन या दूध के साथ लें ताकि पेट में जलन न हो। शराब का सेवन बिल्कुल न करें क्योंकि इससे यकृत को नुकसान और पेट में रक्तस्राव का खतरा बढ़ता है। डॉक्टर की सलाह के बिना कोई अन्य दर्द निवारक दवा न लें। पर्याप्त पानी पिएं। यदि आपको गुर्दे या यकृत की बीमारी है तो डॉक्टर को बताएं। 7 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें।
💊 aclocare-plus oral suspension Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces pain and inflammation in rheumatoid arthritis as an adjunct to disease-modifying therapy.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps relieve pain and stiffness in ankylosing spondylitis.","evidence":"Moderate"},{"condition":"Acute musculoskeletal pain","description":"Used for short-term relief of acute musculoskeletal pain such as sprains, strains, and low back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from dental pain, including post-extraction pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of mild to moderate post-operative pain.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Fever","description":"Paracetamol component may reduce fever, but this combination is not primarily indicated for fever alone.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute musculoskeletal pain, Dental pain, Post-operative pain, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Aceclofenac (100mg) + Paracetamol (250mg) |
| Brand Name | aclocare-plus oral suspension |
| Manufacturer | Carezone Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts predominantly in the central nervous system by inhibiting prostaglandin synthesis and modulating pain perception, and it also affects the hypothalamic heat-regulating center to reduce fever. Together, they provide analgesic, anti-inflammatory, and antipyretic effects.
Mechanism Steps
💡 How to Take aclocare-plus oral suspension
Strength: Tablet containing Aceclofenac 100 mg and Paracetamol 250 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet two to three times daily, depending on the severity of pain and the condition being treated. The maximum daily dose should not exceed three tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate or exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney impairment. Use the lowest effective dose for the shortest duration. Consult a doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose adjustment may be necessary. Consult a doctor. |
| Maximum Daily Dose | Maximum daily dose is 3 tablets in 24 hours. Do not exceed. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aclocare-plus oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| SSRIs | Moderate | |
| Antihypertensives | Moderate | |
| Phenytoin | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
- ACE inhibitors and ARBs
- Diuretics
⚡ Moderate Interactions
- Antihypertensives (beta-blockers, calcium channel blockers)
- SSRIs
- Corticosteroids (inhaled or oral)
- Zidovudine
- Phenytoin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage, especially from Paracetamol, and increases the risk of gastrointestinal bleeding from Aceclofenac.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Aceclofenac, Paracetamol, or any component","Active peptic ulcer or history of recurrent ulcers","Severe heart failure","Severe kidney impairment","Severe liver impairment","Third trimester of pregnancy","Children under 12 years (unless prescribed)","History of asthma, urticaria, or allergic reaction to NSAIDs"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol.","Do not exceed recommended dose or duration.","Use with caution in elderly patients.","Monitor kidney and liver function with long-term use.","May cause dizziness; avoid driving until you know how it affects you.","Consult doctor if symptoms persist beyond 7 days.","Inform your doctor about all other medications you are taking."]
🤱 Lactation Safety
Aceclofenac and Paracetamol are excreted in breast milk in small amounts. Consult your doctor before use. Paracetamol is generally considered safe during breastfeeding, but Aceclofenac should be used with caution.
💊 Overdose Management
Overdose can cause severe liver damage, especially from Paracetamol. Symptoms may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine for Paracetamol toxicity, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine with food or milk to reduce stomach irritation. Do not exceed the prescribed dose or duration. Avoid alcohol completely while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding. Do not take other pain relievers or NSAIDs without consulting your doctor. Stay well hydrated. If you have kidney or liver disease, your doctor may need to adjust the dose or monitor you closely. Do not use this medicine for more than 7 days without medical advice. Keep out of reach of children. Store at room temperature away from moisture and sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are planning pregnancy. NSAIDs may affect ovulation and are not recommended during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain relief, but consult your surgeon before taking it, especially if you are on blood thinners or have kidney problems.
🦷 Dental Procedures
This medicine can be used for dental pain, but inform your dentist about all medicines you are taking. It may increase bleeding risk during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may increase pain while taking this medicine. Gentle stretching and low-impact exercises are generally safe. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Generally, it does not significantly impact daily activities if taken as prescribed.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or kidney problems. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, and liver damage. Regular monitoring of kidney and liver function is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor for alternative treatments if long-term pain management is needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help reduce pain and inflammation.
Evidence: ModerateMay provide pain relief for some conditions.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat or moisture. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines. Keep a list of your medications with you.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.
A: No, alcohol should be avoided while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding.
A: This medicine is generally used for short-term relief. Do not use it for more than 7 days without consulting your doctor.
A: Consult your doctor before taking this medicine during pregnancy. It is not recommended in the third trimester.
🤔 Common Patient Concerns
🔄 Substitutes for aclocare-plus oral suspension
View AllAlternative brands with exact same active ingredient:
-
wellgesic p oral suspensionAltrawell Biotech Pvt Ltd ₹39.38 12.5% CHEAPER
-
manfenac p oral suspensionManlac Pharma ₹45.94 2.1% COSTLIER
-
indard-mr tabletPharma Drugs & Chemicals ₹55.00 22.2% COSTLIER
-
avace p oral suspensionAdenscot Healthcare ₹65.00 44.4% COSTLIER
-
acnac-mr tabletAtishya Biotech ₹70.31 56.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure arthritis.
Fact: This medicine only relieves pain and inflammation; it does not cure arthritis. - Myth: It is safe to take this medicine for a long time without monitoring.
Fact: Long-term use requires monitoring of kidney and liver function and may increase risk of gastrointestinal bleeding. - Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach irritation.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 100 mg + Paracetamol 250 mg tablet
Brand Alternatives
- Aceclo-P
- Aceclofenac-Paracetamol
- Hifenac-P
- Zerodol-P
- Acenac-P