Acimar Syrup: Complete Guide to Uses, Dosage, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black tarry stools
- Severe or worsening abdominal pain
- Difficulty swallowing or food sticking in the throat
- Unexplained weight loss or persistent vomiting
- Chest pain, breathlessness, or sweating that could suggest a heart problem
- Swelling of the face, lips, or throat, or difficulty breathing
- Confusion, muscle weakness, or slow heartbeat suggesting electrolyte imbalance
- Reduced urine output or swelling of the legs in kidney disease
If experiencing severe symptoms, call emergency services immediately.
What is acimar syrup used for?
This medicine is an oral antacid and antifoaming syrup containing magaldrate and simethicone. It neutralises stomach acid and helps relieve trapped gas, providing short-term relief from heartburn, indigestion, and bloating. It is usually taken after meals or at bedtime, and it should not be used for more than two weeks without medical advice.
- Generic Name: Magaldrate + Simethicone
- Manufacturer: Medok Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acimar syrup के बारे में (Hindi Summary)
उपयोग: यह दवा मैगल्ड्रेट और सिमेथिकोन का मिश्रण है, जो सिरप के रूप में मुँह से ली जाती है। यह पेट की अतिरिक्त अम्लता को कम करती है और पेट में जमी गैस को बाहर निकालने में मदद करती है। इसका उपयोग सीने में जलन, खट्टी डकार, अपच, पेट में भारीपन और गैस के कारण होने वाली असुविधा में राहत के लिए किया जाता है। यह दवा लक्षणों को कम करती है, लेकिन अल्सर या रिफ्लक्स जैसी बीमारी का इलाज नहीं करती। इसे खाने के बाद या रात में सोने से पहले लिया जा सकता है। दो हफ्तों से ज्यादा इसका इस्तेमाल बिना डॉक्टर की सलाह के न करें। गुर्दे की बीमारी वाले मरीज इसे डॉक्टर की सलाह के बिना न लें।
साइड इफेक्ट्स: इस दवा को सही मात्रा में लेने पर ज्यादातर लोगों को कोई परेशानी नहीं होती। कुछ लोगों को दस्त, कब्ज, जी मिचलाना, पेट में ऐंठन, या मुँह में चॉक जैसा स्वाद महसूस हो सकता है। कभी-कभी डकार या मुँह सूखना भी हो सकता है। गुर्दे की बीमारी वाले लोगों में लंबे समय तक इस्तेमाल से मैग्नीशियम या एल्युमिनियम का स्तर बढ़ सकता है, जिससे कमजोरी, भ्रम, धड़कन धीमी होना या ब्लड प्रेशर गिरना जैसी गंभीर समस्याएँ हो सकती हैं। अगर चेहरे, होंठ या गले में सूजन, साँस लेने में तकलीफ, या त्वचा पर चकत्ते दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को लेबल या डॉक्टर के बताए अनुसार ही लें। सिरप को हर बार अच्छी तरह हिलाएँ और दवा के साथ दिए गए चम्मच या कप से ही मात्रा नापें। दूसरी दवाओं के साथ इसे लेने से पहले कम से कम दो घंटे का अंतर रखें, क्योंकि यह कई दवाओं के असर को कम कर सकती है। दो हफ्तों से ज्यादा बिना डॉक्टर की सलाह के इसका इस्तेमाल न करें। अगर काला मल, खून की उल्टी, निगलने में तकलीफ, या वजन कम होना जैसी शिकायत हो तो तुरंत डॉक्टर से मिलें। गुर्दे की बीमारी, हृदय रोग या इलेक्ट्रोलाइट की समस्या वाले मरीज डॉक्टर से पूछकर ही इसे लें। गर्भवती और स्तनपान कराने वाली महिलाएँ पहले डॉक्टर से सलाह लें। बोतल को ठंडी, सूखी जगह पर रखें और बच्चों की पहुँच से दूर रखें।
💊 acimar syrup Uses & Benefits
[{"condition":"Heartburn and acid indigestion","description":"Provides rapid neutralisation of gastric acid and relieves the burning discomfort behind the breastbone that occurs after meals or on lying down.","evidence":"Well-established"},{"condition":"Gastro-oesophageal reflux symptoms","description":"Used for short-term relief of mild reflux symptoms such as regurgitation, sour taste, and retrosternal burning when lifestyle measures alone are insufficient.","evidence":"Well-established"},{"condition":"Functional dyspepsia with bloating","description":"The simethicone component helps reduce trapped gas and abdominal fullness, while magaldrate reduces acid-related upper abdominal discomfort.","evidence":"Moderate"},{"condition":"Postprandial epigastric distress","description":"Relieves fullness, belching, and discomfort after heavy or spicy meals in people without alarm features.","evidence":"Moderate"},{"condition":"Antacid cover for minor gastric irritation","description":"Sometimes used for short-term relief of mild medication-related or dietary gastric irritation after clinician assessment.","evidence":"Limited"}]
Off-label uses: [{"condition":"Pre-procedure gastric acid neutralisation","description":"Occasionally used by clinicians to reduce gastric acidity before certain procedures, but this is not a standard labelled use of this combination.","evidence":"Limited"},{"condition":"Hiccups associated with gastric distension","description":"Simethicone-containing antacids are sometimes tried for hiccups thought to be related to swallowed air or gastric gas, but evidence is weak.","evidence":"Limited"}]
Primary treatment for: Acid-related dyspepsia and heartburn
Also treats: Gastro-oesophageal reflux disease with mild symptoms, Functional dyspepsia with bloating, Postprandial epigastric discomfort, Gas-related abdominal fullness
📋 Drug Information
| Generic Name(s) | Magaldrate + Simethicone |
| Brand Name | Aciloc-S Suspension Sugar Free |
| Manufacturer | Medok Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antacid + Antiflatulent |
| Route of Administration | Oral. This medicine is a syrup that is swallowed after being measured with the supplied spoon or cup. It should not be injected or applied to the skin |
| Storage | Store at room temperature, generally between 15°C and 30°C, in a dry place away from direct sunlight. Keep the bottle tightly closed after each use. Do not freeze the syrup. Keep it out of reach of children and away from heat sources. |
| Shelf Life | Not established from the available information for this specific product. Check the expiry date printed on the bottle and do not use the syrup after that date. |
| WHO Guideline | Not established from the available information for this specific product. Antacids and simethicone are widely used for symptomatic relief, but this profile does not claim a specific WHO recommendation for this combination. |
| ICMR Guideline | Not established from the available information for this specific product. Patients in India should follow advice from their treating clinician and national prescribing guidance where available. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by two complementary mechanisms in the stomach and upper intestine. Magaldrate is a chemical complex of aluminium and magnesium hydroxides with sulphate; in the acidic environment of the stomach it reacts with hydrochloric acid to form aluminium and magnesium salts and water, thereby raising gastric pH and reducing the irritant effect of acid on the oesophageal and gastric mucosa. Because it is a balanced salt, it is designed to minimise the constipating effect of aluminium and the laxative effect of magnesium. Simethicone is a polydimethylsiloxane with surface-active properties; it lowers the surface tension of gas bubbles in the gastrointestinal tract, causing small bubbles to coalesce into larger ones that are more easily expelled by belching or passed per rectum. Simethicone is not absorbed systemically to any meaningful extent and does not reduce acid secretion; it acts physically on foam and gas. The combination therefore addresses both acid-related burning and gas-related bloating, which frequently occur together.
Mechanism Steps
💡 How to Take acimar syrup
Strength: Syrup containing magaldrate 40 mg and simethicone 20 mg per stated unit of the product, as supplied by the manufacturer. The exact volume per dose should be measured with the device provided with the bottle.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one to two teaspoonfuls or the volume specified on the label, taken orally as needed for heartburn, indigestion, or bloating, usually after meals and at bedtime. The exact dose and frequency depend on the severity of symptoms, the underlying condition, and the clinician's assessment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the maximum daily dose stated on the label, and do not use this medicine continuously for more than two weeks without medical review. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific product. Antacid and simethicone syrups are sometimes used in children, but the dose depends on age, weight, and the specific product concentration. Consult a pediatrician before giving this medicine to a child. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of aluminium and magnesium salts, especially if kidney function is reduced. The dose should be kept as low as possible for the shortest duration needed, and kidney function should be checked if use is prolonged. Dose must be individualized by a qualified clinician based on renal function and other medicines being taken. |
| Renal Impairment | Patients with kidney impairment should avoid this medicine or use it only under close medical supervision because aluminium and magnesium can accumulate and cause toxicity. If use is unavoidable, the lowest effective dose should be used for the shortest possible time, with monitoring of magnesium, calcium, and kidney function. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment because magaldrate acts locally and simethicone is not absorbed. However, patients with liver disease and fluid or electrolyte disturbances should use this medicine cautiously and only after consulting a clinician. |
| Maximum Daily Dose | Not established from the available information for this specific product. Do not exceed the maximum daily dose printed on the product label or advised by your clinician. Prolonged use above the recommended dose increases the risk of electrolyte and mineral imbalances. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acimar syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Tetracycline | Major | |
| Ciprofloxacin | Major | |
| Levothyroxine | Major | |
| Iron salts | Major | |
| Alendronate | Moderate | |
| Ketoconazole | Moderate | |
| Atazanavir | Moderate | |
| Sodium polystyrene sulfonate | Moderate | |
| Digoxin | Minor | |
| Paracetamol | Minor |
🚨 Major Interactions
- Tetracycline and doxycycline antibiotics
- Fluoroquinolone antibiotics such as ciprofloxacin and levofloxacin
- Levothyroxine
- Iron salts
⚡ Moderate Interactions
- Bisphosphonates such as alendronate
- Ketoconazole and itraconazole
- Atazanavir and other protease inhibitors
- Sodium polystyrene sulfonate
🍷 Alcohol Interaction
Alcohol can irritate the stomach lining, increase acid secretion, and worsen heartburn and gastritis, which works against the purpose of this medicine. Alcohol does not have a direct chemical interaction with magaldrate or simethicone, but drinking heavily while relying on this medicine can mask serious stomach problems and delay proper diagnosis. It is best to avoid alcohol or keep intake minimal while you are being treated for acid-related symptoms.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to magaldrate, simethicone, or any component of the syrup","Severe renal impairment or chronic kidney disease without medical supervision","Suspected or confirmed gastrointestinal obstruction or perforation","Severe abdominal pain of unknown cause","Uncontrolled hypermagnesaemia or hypercalcaemia","Use in children below the age recommended by the manufacturer or clinician"]
⚠️ Warnings & Precautions
["Do not use this medicine for more than two weeks without medical advice.","Separate this medicine from other oral medicines by at least two hours because it can reduce their absorption.","Use with caution in elderly patients and in those with kidney disease, heart failure, or electrolyte disorders.","Avoid combining with large amounts of calcium supplements or other antacids to reduce the risk of milk-alkali syndrome.","Stop the medicine and seek medical help if you develop black stools, vomiting of blood, difficulty swallowing, or unexplained weight loss.","Shake the bottle well before each dose and use the measuring device supplied with the product.","Keep out of reach of children and do not use after the expiry date."]
🤱 Lactation Safety
Not established from the available information for this specific product. Aluminium and magnesium salts are poorly absorbed, so systemic exposure to the breastfed infant is expected to be low, and simethicone is not absorbed. Breastfeeding women should still check with a clinician before using this medicine, especially if the infant has kidney problems or if prolonged use is planned.
💊 Overdose Management
Overdose with this medicine can cause gastrointestinal upset, diarrhoea, and, with large amounts, electrolyte and acid-base disturbances such as metabolic alkalosis, hypermagnesaemia, or hypercalcaemia. Treatment is supportive and depends on symptoms and laboratory findings. If a large amount has been taken, contact a poison control centre or go to the nearest emergency department. Do not induce vomiting unless instructed by a healthcare professional. Bring the bottle or packaging so that the exact ingredients and strength can be identified. Patients with kidney disease may need closer monitoring of magnesium, calcium, and kidney function.
⏰ Missed Dose
This medicine is usually taken when symptoms occur, so a strict missed-dose schedule may not apply. If you are on a regular schedule and miss a dose, take it as soon as you remember unless it is almost time for the next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, ask your pharmacist or doctor.
Additional Safety Advice
Take this medicine exactly as directed on the label or by your clinician, and shake the bottle well before each dose because it is a suspension. Measure doses with the supplied spoon or cup rather than a household spoon so that the amount is accurate. Separate this medicine from other oral medicines by at least two hours, because antacids can bind or alter the absorption of many drugs, including antibiotics, thyroid medicines, iron, and some heart medicines. Do not use this medicine for more than two weeks without medical advice, and do not use it to treat unexplained weight loss, difficulty swallowing, persistent vomiting, black stools, or blood in vomit. People with kidney disease, heart failure, or a history of electrolyte problems should ask a doctor before using it. Pregnant or breastfeeding women should check with a clinician first. Keep the bottle tightly closed, out of reach of children, and do not use it after the expiry date. If you are taking any prescription medicine, tell your pharmacist before starting this product so that interactions can be checked.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to have reduced kidney function and to take multiple medicines, which increases the risk of interactions and mineral accumulation. This medicine should be used at the lowest effective dose for the shortest time, and kidney function should be checked if use is prolonged. Elderly patients should also be monitored for confusion, weakness, or slow heartbeat, which can indicate electrolyte problems.
🤰 Pregnancy Planning (TTC)
If you are trying to conceive or are pregnant, talk to your doctor before using this medicine. Short-term use of aluminium and magnesium antacids is often considered acceptable in pregnancy, but simethicone data are limited, and prolonged or high-dose use should be avoided. Your clinician can recommend the safest option for your symptoms.
🏥 Post-Surgery Considerations
After surgery, especially abdominal surgery, do not take this medicine without asking your surgeon or doctor. Antacids can interfere with other medicines, affect electrolyte balance, and may be inappropriate if there is a risk of obstruction or impaired kidney function. Follow your surgical team's instructions on when it is safe to resume antacids.
🦷 Dental Procedures
This medicine does not usually interfere with dental procedures. However, if you are having sedation or surgery, tell your dentist or anaesthetist about all medicines you take, including this syrup. If you have difficulty swallowing or need to lie flat for a long procedure, discuss your reflux symptoms with your dentist beforehand.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Light to moderate exercise is generally safe while taking this medicine. Avoid vigorous exercise immediately after a heavy meal because it can worsen reflux and bloating. If you feel dizzy, weak, or unwell, stop exercising and seek medical advice. People with heart or kidney disease should follow their clinician's exercise recommendations.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to work or drive. It does not usually cause drowsiness. However, if you feel dizzy, weak, or unwell from any cause, avoid driving or operating heavy machinery until you feel better. Taking the syrup at work is simple if you carry the bottle and measuring cup, but keep it away from heat and direct sunlight.
🛑 When to Stop This Medicine
Stop this medicine and seek medical advice if your symptoms do not improve within two weeks, if they worsen, or if you develop alarm features such as difficulty swallowing, black stools, vomiting of blood, or unexplained weight loss. Do not stop any other prescribed medicine without talking to your doctor. If you have kidney disease, your doctor may advise stopping this medicine altogether or using it only occasionally.
📅 Long-Term Use Effects
Long-term or excessive use of this medicine can lead to accumulation of aluminium and magnesium, especially in people with kidney disease, and can cause hypermagnesaemia, aluminium toxicity, metabolic alkalosis, or milk-alkali syndrome. It can also mask serious conditions such as peptic ulcer, oesophageal disease, or stomach cancer, delaying diagnosis. Prolonged use may interfere with the absorption of nutrients and other medicines. If symptoms persist beyond two weeks, a clinician should reassess the cause and consider whether a different treatment is needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Smaller meals, avoiding trigger foods, weight management, and elevating the head of the bed can reduce reflux symptoms.
Evidence: Well-establishedUsed for frequent or persistent reflux and ulcer disease after medical assessment.
Evidence: Well-establishedAlternative acid suppression for milder or intermittent symptoms.
Evidence: Well-establishedCan help reduce functional dyspepsia symptoms in some patients.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no known interaction between this medicine and routine vaccines. If you are unwell with fever or severe symptoms, it is usually better to postpone vaccination until you have recovered, as advised by your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not freeze the syrup
✅ DO
Keep the bottle tightly closed after each use
❌ DON'T
Do not leave the cap loose or open
✅ DO
Keep away from direct sunlight and heat
❌ DON'T
Do not store near a stove or in a hot car
✅ DO
Keep out of reach of children
❌ DON'T
Do not transfer the syrup to an unlabelled container
✈️ Traveling with This Medicine
Carry this medicine in its original labelled bottle with the measuring cup, and keep a copy of the prescription or a note from your doctor if you are travelling internationally. Store it in hand luggage rather than checked baggage so that it is not exposed to extreme temperatures. If you are crossing time zones and take the medicine on a regular schedule, continue doses at the same intervals as prescribed rather than doubling up. Check customs rules for liquid medicines in your destination country, and carry only the amount you need for the trip. If the syrup leaks or the bottle is damaged, replace it rather than transferring the medicine to another container.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Relief of heartburn usually begins within a few minutes because the antacid neutralises stomach acid directly. The effect on bloating and gas may take a little longer.
A: You can, but you should separate this medicine from other oral medicines by at least two hours because it can reduce their absorption. Always tell your pharmacist about all medicines you take.
A: It is intended for short-term relief. Prolonged use without medical review can cause mineral and electrolyte imbalances, especially in people with kidney disease, and can mask serious conditions.
A: Antacids are often used in pregnancy for short-term relief, but you should check with your doctor or pharmacist first, especially if you need it for more than a few days.
A: If you are on a regular schedule, take the missed dose when you remember unless it is almost time for the next dose. Do not double the dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine cures the root cause of acidity.
Fact: This medicine provides symptomatic relief by neutralising acid and reducing gas; it does not cure underlying conditions such as ulcer disease or reflux disease. - Myth: More syrup gives faster and better relief.
Fact: Taking more than the recommended dose does not improve relief and increases the risk of electrolyte and mineral imbalances. - Myth: It is safe to take every day for months.
Fact: Prolonged daily use without medical review can cause magnesium or aluminium accumulation, especially in kidney disease, and can mask serious conditions. - Myth: It can be taken at the same time as all other medicines.
Fact: Antacids can reduce the absorption of many medicines, so doses should be separated by at least two hours.
🔄 Alternative Options
Generic Alternatives
- Magaldrate and simethicone oral suspension
- Magaldrate oral suspension
- Simethicone oral emulsion