Acifrox 250 Tablet DT - Uses, Price, Side Effects
What is acifrox 250 tablet dt used for?
Acifrox 250 Tablet DT is an antibiotic used to treat bacterial infections of the respiratory tract, ear, nose, throat, skin, and urinary tract. It contains Cefuroxime, a cephalosporin that works by stopping the growth of bacteria. Take it as prescribed, usually twice daily with or without food.
- Generic Name: Cefuroxime
- Manufacturer: Axico Healthcare
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ acifrox 250 tablet dt Uses & Benefits
Upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, gonorrhea, Lyme disease.
Off-label uses: Prophylaxis for surgical infections, treatment of bone and joint infections.
๐ Drug Information
| Generic Name(s) | Cefuroxime |
| Brand Name | Altacef 500 Tablet |
| Manufacturer | Axico Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 2nd generation |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase and autolysin activity.
Mechanism Steps
๐ก How to Take acifrox 250 tablet dt
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of acifrox 250 tablet dt
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Injection site reactions (if IV)
๐จ Serious Side Effects
- Severe allergic reactions (anaphylaxis)
- Clostridioides difficile diarrhea
- Seizures (high doses)
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Interstitial nephritis
- Hepatitis
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Probenecid | Moderate | Reduced excretion of cefuroxime |
| Loop diuretics | Moderate | Increased nephrotoxicity risk |
๐จ Major Interactions
- Warfarin
- Probenecid
- Live typhoid vaccine
- BCG vaccine
โก Moderate Interactions
- Loop diuretics
- Aminoglycosides
- Oral contraceptives
- BCG (intravesical)
โน๏ธ Minor Interactions
- Antacids
- H2 antagonists
- Proton pump inhibitors
๐ฝ๏ธ Food Interactions
Food increases absorption; take with food.
๐ท Alcohol Interaction
No known interaction; but may increase risk of disulfiram-like reaction (rare).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cefuroxime or other cephalosporins; previous immediate hypersensitivity reaction to penicillins.
๐ Monitoring Parameters
Renal function, signs of hypersensitivity, superinfection, bleeding (if on warfarin).
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; generally considered compatible with breastfeeding.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for acifrox 250 tablet dt
View AllAlternative brands with exact same active ingredient (Cefuroxime (250mg)):
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wezcef 250mg tabletWezen Chemicals Pvt Ltd โน20.00 88% CHEAPER
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Rokz 250mg TabletEclipser Pharmaceuticals โน22.00 86.8% CHEAPER
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xime 250mg syrupPCI Pharmaceuticals โน23.87 85.7% CHEAPER
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Roxef 250mg InjectionReco Drugs โน25.00 85% CHEAPER
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wyceft 250mg tabletVostok & Wilcure Remedies โน26.00 84.4% CHEAPER
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Cefa 250mg TabletWest-Coast Pharmaceutical Works Ltd โน27.40 83.6% CHEAPER
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jectocef 250mg injectionTrident Pharma โน28.40 83% CHEAPER
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cefro 250mg tabletMefro Pharmaceuticals Pvt Ltd โน30.50 81.7% CHEAPER
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axcef 250mg injectionMidas Biotek Pvt Ltd โน32.81 80.3% CHEAPER
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cefactin 250mg tabletGlenmark Pharmaceuticals Ltd โน32.81 80.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.