Acidom 20mg/20mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular or racing heartbeat, palpitations, or fainting
- Severe allergic reaction with swelling of face, lips, tongue, or throat, or difficulty breathing
- Blood in vomit or black, tarry stools
- Severe abdominal pain or persistent vomiting
- Signs of low magnesium such as muscle cramps, tremors, or seizures
- Yellowing of skin or eyes (jaundice)
- Unusual bruising or bleeding
- Severe, watery diarrhoea that does not improve
If experiencing severe symptoms, call emergency services immediately.
What is acidom 20mg/20mg tablet used for?
This medicine is a combination of Domperidone and Rabeprazole used to treat acid reflux, heartburn, and nausea. It works by reducing stomach acid and helping the stomach empty faster. It is usually taken once daily before breakfast.
- Generic Name: Domperidone + Rabeprazole
- Manufacturer: Sienna Formulations Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acidom 20mg/20mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन और रेबेप्राजोल का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, सीने में जलन, और मतली को कम करने के लिए किया जाता है। यह पेट में एसिड का उत्पादन कम करती है और पेट को जल्दी खाली करने में मदद करती है। इसे आमतौर पर नाश्ते से 30-60 मिनट पहले खाली पेट लिया जाता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुँह सूखना, सिरदर्द, दस्त, पेट दर्द और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन दिल की धड़कन अनियमित होना, गंभीर एलर्जी, या लंबे समय तक उपयोग से मैग्नीशियम और विटामिन बी12 की कमी हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को खाली पेट, भोजन से 30-60 मिनट पहले लें। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। निर्धारित खुराक से अधिक न लें। शराब से बचें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको हृदय, गुर्दे या यकृत की बीमारी है, तो डॉक्टर से सलाह लें। लंबे समय तक उपयोग से पहले डॉक्टर से परामर्श करें।
💊 acidom 20mg/20mg tablet Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces acid reflux and heartburn by decreasing stomach acid production and helping the stomach empty faster.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Relieves symptoms such as upper abdominal discomfort, bloating, and early fullness after meals.","evidence":"Well-established"},{"condition":"Nausea and vomiting associated with acid-related disorders","description":"Domperidone helps control nausea and vomiting while Rabeprazole treats the underlying acid problem.","evidence":"Moderate"},{"condition":"Gastroparesis (delayed stomach emptying)","description":"Domperidone improves stomach emptying, which can reduce nausea, vomiting, and bloating.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Refractory nausea and vomiting in palliative care","description":"Sometimes used off-label when other treatments fail, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Gastroparesis, Nausea and vomiting associated with acid-related disorders
📋 Drug Information
| Generic Name(s) | Domperidone + Rabeprazole |
| Brand Name | Acera-D Capsule SR |
| Manufacturer | Sienna Formulations Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from direct sunlight, moisture, and heat. Do not refrigerate unless specifically instructed. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Domperidone is a peripheral dopamine D2 receptor antagonist that blocks dopamine receptors in the chemoreceptor trigger zone and the stomach, leading to faster gastric emptying and reduced nausea. Rabeprazole is a proton pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase enzyme in the stomach lining, suppressing both basal and stimulated acid secretion.
Mechanism Steps
💡 How to Take acidom 20mg/20mg tablet
Strength: Each tablet contains Domperidone 20 mg and Rabeprazole 20 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, preferably 30 to 60 minutes before breakfast on an empty stomach. However, the exact dose and duration depend on the condition being treated, your age, kidney and liver function, and other medicines you take. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially heart rhythm problems and dizziness. The dose may need to be adjusted by a doctor based on kidney and liver function. Regular monitoring is advised. |
| Renal Impairment | In patients with severe kidney disease, the dose of Domperidone may need to be reduced, and Rabeprazole should be used with caution. Consult your doctor for dose adjustment. |
| Hepatic Impairment | This medicine should be used with caution in patients with liver disease. Dose reduction may be necessary, and liver function should be monitored. In severe liver disease, this medicine is contraindicated. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (Domperidone 20 mg + Rabeprazole 20 mg) per day. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acidom 20mg/20mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Amiodarone | Major | |
| Warfarin | Moderate | |
| Atazanavir | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor | |
| Sucralfate | Minor | |
| Methotrexate | Major | |
| Clarithromycin | Major | |
| Ritonavir | Major |
🚨 Major Interactions
- Ketoconazole, itraconazole, clarithromycin, ritonavir
- Amiodarone, sotalol, quinidine, haloperidol
- Methotrexate
⚡ Moderate Interactions
- Warfarin
- Atazanavir, nelfinavir
- Digoxin
🍷 Alcohol Interaction
Alcohol can worsen stomach irritation and increase the risk of gastrointestinal bleeding. It may also add to drowsiness or dizziness. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to Domperidone, Rabeprazole, or any component of this medicine","Gastrointestinal obstruction, perforation, or active bleeding","Prolactin-releasing pituitary tumour (prolactinoma)","Severe liver disease","Severe kidney disease","Known QT prolongation or family history of long QT syndrome","Concomitant use with strong CYP3A4 inhibitors that prolong QT interval"]
⚠️ Warnings & Precautions
["This medicine may cause a serious heart rhythm problem called QT prolongation. Tell your doctor if you have heart disease or take other medicines that affect heart rhythm.","Do not take more than the recommended dose, as higher doses increase the risk of heart rhythm problems.","Use with caution in elderly patients, who may be more sensitive to side effects.","Long-term use of Rabeprazole may increase the risk of bone fractures, low magnesium, and vitamin B12 deficiency.","This medicine may mask symptoms of stomach cancer. Your doctor may need to rule out cancer before starting treatment.","Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause dizziness.","Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Domperidone passes into breast milk and may cause side effects in the baby. Rabeprazole may also pass into breast milk. This medicine is not recommended during breastfeeding unless your doctor decides the benefits outweigh the risks.
💊 Overdose Management
If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe drowsiness, irregular heartbeat, confusion, or fainting. Treatment is supportive and may include monitoring of heart rhythm and vital signs. There is no specific antidote for Domperidone or Rabeprazole; activated charcoal may be considered if the overdose is recent.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is more than 12 hours before your next scheduled dose. If it is less than 12 hours before your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine on an empty stomach, at least 30 to 60 minutes before a meal, unless your doctor tells you otherwise. Swallow the tablet whole with a glass of water; do not crush or chew it. Do not take more than the prescribed dose, because higher doses of Domperidone can increase the risk of heart rhythm problems. Avoid drinking alcohol while taking this medicine, as it can worsen stomach irritation and increase drowsiness. If you have kidney or liver problems, your doctor may need to adjust the dose or monitor you more closely. Do not use this medicine for longer than your doctor recommends without a review. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before taking this medicine. Keep all follow-up appointments so your doctor can check how well the medicine is working and whether you need to continue it.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of QT prolongation, electrolyte imbalances, and drug interactions. The dose may need to be adjusted, and regular monitoring of heart rhythm, kidney function, and magnesium levels is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss this medicine with your doctor. It may need to be stopped or changed to a safer alternative before conception.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used to prevent nausea and vomiting, but it should be used with caution due to the risk of QT prolongation. Inform your surgeon and anaesthesiologist about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with certain anaesthetics or medications used during dental procedures. It is generally safe to continue, but your dentist may recommend precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid vigorous exercise immediately after meals, as it can worsen reflux. If you experience dizziness or palpitations during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not significantly impact your ability to work, but take precautions if you feel unsteady.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like irregular heartbeat, severe allergic reaction, or persistent diarrhoea, seek medical advice immediately. Your doctor will decide if and when to stop the medicine based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to low magnesium levels, vitamin B12 deficiency, and an increased risk of bone fractures due to Rabeprazole. Domperidone can cause elevated prolactin levels, leading to breast tenderness or discharge. Regular monitoring of magnesium, vitamin B12, and bone health may be needed. Your doctor should review the need for continued use periodically.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and elevating the head of the bed can reduce reflux symptoms.
Evidence: Well-establishedPantoprazole or omeprazole may be used instead of Rabeprazole, depending on tolerance and availability.
Evidence: Well-establishedRanitidine or famotidine may be alternatives for milder acid suppression.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for any vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If you are crossing time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Keep enough supply for your entire trip, and check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Domperidone starts working within 30-60 minutes to relieve nausea and improve stomach emptying. Rabeprazole begins reducing acid within 1 hour, but maximum benefit for acid-related symptoms may take 1-4 days of regular use.
A: It can interact with several medicines, including ketoconazole, amiodarone, warfarin, and methotrexate. Always inform your doctor about all medicines you are taking.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor before taking it if you are pregnant or planning to become pregnant.
A: It is best to avoid alcohol, as it can worsen stomach irritation and increase drowsiness.
🤔 Common Patient Concerns
🔄 Substitutes for acidom 20mg/20mg tablet
View AllAlternative brands with exact same active ingredient:
-
hinrab dsr capsulePerk Pharmaceuticals Ltd ₹33.94 34.2% CHEAPER
-
arab d 20mg/20mg tablet srMediwell Laboratories ₹56.25 9.1% COSTLIER
-
rabin-dxr capsule srInvision Medi Sciences Pvt Ltd ₹62.83 21.9% COSTLIER
-
Rabecer D 20mg/20mg TabletCipla Ltd ₹70.08 35.9% COSTLIER
-
rd 20mg/20mg capsule srClox Pharma Pvt Ltd ₹70.31 36.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken anytime, with or without food.
Fact: It should be taken on an empty stomach, at least 30-60 minutes before a meal, for best effect. - Myth: It is safe to take this medicine for as long as you want.
Fact: Long-term use should be reviewed by a doctor because of potential side effects like low magnesium and bone fractures. - Myth: This medicine is a painkiller.
Fact: It is not a painkiller; it reduces acid and nausea but does not treat pain directly.
🔄 Alternative Options
Generic Alternatives
- Domperidone + Rabeprazole generic tablets