acetol 400mg tablet cr - Uses, Price, Side Effects & Substitutes
What is acetol 400mg tablet cr used for?
Acetol 200mg Tablet CR (Carbamazepine) is used to treat NEURO CNS. It contains Carbamazepine (400mg), which Stabilizes neuronal membranes by blocking voltage-gated sodium channels, reducin. Always consult your doctor before use. Take as prescribed.
- Generic Name: Carbamazepine
- Manufacturer: Psychotropics India Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ acetol 400mg tablet cr Uses & Benefits
Epilepsy (partial and generalized tonic-clonic seizures), trigeminal neuralgia, bipolar disorder (mania).
Off-label uses: Diabetic neuropathy, postherpetic neuralgia, alcohol withdrawal, ADHD, schizophrenia (adjunct).
๐ Drug Information
| Generic Name(s) | Carbamazepine |
| Brand Name | Acetol 200mg Tablet CR |
| Manufacturer | Psychotropics India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Sodium channel modulators (AED) |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Stabilizes neuronal membranes by blocking voltage-gated sodium channels, reducing repetitive firing of action potentials.
Mechanism Steps
๐ก How to Take acetol 400mg tablet cr
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of acetol 400mg tablet cr
โ Common Side Effects
- Dizziness
- Drowsiness
- Ataxia
- Nausea
- Vomiting
- Blurred vision
- Diplopia
- Fatigue
- Headache
- Dry mouth
๐จ Serious Side Effects
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Aplastic anemia
- Agranulocytosis
- Hepatitis
- Pancreatitis
- Cardiac arrhythmias
- SIADH
- Hypersensitivity reactions
โ ๏ธ Rare Side Effects
- Lupus-like syndrome
- Peripheral neuropathy
- Osteomalacia
- Gynecomastia
- Pulmonary fibrosis
- Renal failure
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased metabolism of warfarin, reducing anticoagulant effect. |
| Oral contraceptives | Major | Reduced efficacy of oral contraceptives; use alternative contraception. |
| Theophylline | Major | Decreased theophylline levels. |
| Phenytoin | Major | Complex interaction; may decrease phenytoin levels. |
| Valproic acid | Major | Decreased valproate levels; increased risk of hepatotoxicity. |
| Lamotrigine | Major | Decreased lamotrigine levels; increased risk of Stevens-Johnson syndrome. |
| Risperidone | Major | Decreased risperidone levels. |
| Aripiprazole | Major | Decreased aripiprazole levels. |
| Haloperidol | Major | Decreased haloperidol levels. |
| Methadone | Major | Decreased methadone levels; may precipitate withdrawal. |
| Cyclosporine | Major | Decreased cyclosporine levels. |
| Doxycycline | Major | Decreased doxycycline levels. |
| Felodipine | Major | Decreased felodipine levels. |
| Itraconazole | Major | Decreased itraconazole levels. |
| Ketoconazole | Major | Decreased ketoconazole levels. |
| Tramadol | Major | Decreased tramadol levels; increased seizure risk. |
| Topiramate | Major | Decreased topiramate levels. |
| Zonisamide | Major | Decreased zonisamide levels. |
๐จ Major Interactions
- Warfarin
- Oral contraceptives
- Theophylline
- Phenytoin
- Valproic acid
- Lamotrigine
- Risperidone
- Aripiprazole
- Haloperidol
- Methadone
- Cyclosporine
- Doxycycline
- Felodipine
- Itraconazole
- Ketoconazole
- Tramadol
- Topiramate
- Zonisamide
โก Moderate Interactions
- Acetaminophen
- Alprazolam
- Bupropion
- Citalopram
- Clonazepam
- Diazepam
- Lorazepam
- Olanzapine
- Quetiapine
- Sertraline
- Venlafaxine
- Warfarin (minor effect)
โน๏ธ Minor Interactions
- Caffeine
- Theophylline (minor)
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase carbamazepine levels; avoid. Food may affect absorption but not significantly.
๐ท Alcohol Interaction
May increase CNS depression and reduce seizure threshold; avoid alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
History of bone marrow depression, hypersensitivity to carbamazepine or tricyclic antidepressants, MAO inhibitor use within 14 days, AV block, porphyria.
๐ Monitoring Parameters
CBC, liver function tests, renal function, serum carbamazepine levels (therapeutic range 4-12 mcg/mL), ECG in elderly or cardiac patients.
๐คฑ Lactation Safety
Excreted in breast milk; monitor infant for drowsiness and poor feeding; generally considered compat
๐ Overdose Management
Supportive care; activated charcoal if recent ingestion; monitor cardiac, respiratory, and CNS status; consider hemodialysis in severe cases.
โฐ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for acetol 400mg tablet cr
View AllAlternative brands with exact same active ingredient (Carbamazepine (400mg)):
-
Fobigone 400mg Tablet SRMarc Laboratories Pvt Ltd โน19.68 22.8% CHEAPER
-
carbesta 400mg tablet crArinna Lifescience Pvt Ltd โน21.13 17.1% CHEAPER
-
epilent 400mg tablet srTalent Healthcare โน23.71 7% CHEAPER
-
carbetol 400mg tablet crTaj Pharma India Ltd โน24.10 5.5% CHEAPER
-
zeptol 400mg tabletSun Pharmaceutical Industries Ltd โน24.77 2.9% CHEAPER
-
zepcar 400mg tablet crAlkem Laboratories Ltd โน24.77 2.9% CHEAPER
-
maze 400mg tablet srAarpik Pharmaceuticals Pvt Ltd โน25.28 0.9% CHEAPER
-
carbasure 400mg tabletGentech Healthcare Pvt Ltd โน26.00 2% COSTLIER
-
carbacontin 400mg tabletModi Mundi Pharma Pvt Ltd โน26.16 2.6% COSTLIER
-
mezaril 400mg tablet srReliance Formulation Pvt Ltd โน26.85 5.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.