aceten 12.5mg tablet - Captopril (12.5mg) medicine

aceten 12.5mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Wockhardt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is aceten 12.5mg tablet used for?

Aceten (Captopril) is used to treat CARDIAC. It contains Captopril (12.5mg), which Inhibits angiotensin-converting enzyme (ACE), preventing conversion of angiotens. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Captopril
  • Manufacturer: Wockhardt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š aceten 12.5mg tablet Uses & Benefits

Hypertension, heart failure, post-myocardial infarction, diabetic nephropathy.

Off-label uses: Scleroderma renal crisis, hypertensive emergencies (IV form), Raynaud's phenomenon.

๐Ÿ“‹ Drug Information

Generic Name(s)Captopril
Brand NameAceten
ManufacturerWockhardt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin-converting enzyme (ACE) inhibitors
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract; oral bioavailability about 75%.
DistributionDistributed throughout the body; crosses placenta but not blood-brain barrier.
Protein Binding25-30% bound to plasma proteins.
MetabolismPartially metabolized in the liver to inactive metabolites.
Half-LifeApproximately 2 hours (prolonged in renal impairment).
ExcretionPrimarily excreted in urine (95% as unchanged drug and metabolites).
Bioavailability75%
Onset of Action15-30 minutes
Peak Plasma Time1-1.5 hours
Duration of Action6-12 hours

How It Works

Inhibits angiotensin-converting enzyme (ACE), preventing conversion of angiotensin I to angiotensin II, reducing vasoconstriction and aldosterone secretion.

Mechanism Steps

1Captopril binds to the active site of ACE.
2Inhibits conversion of angiotensin I to angiotensin II.
3Reduces angiotensin II levels, leading to vasodilation.

๐Ÿ’ก How to Take aceten 12.5mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aceten 12.5mg tablet

โœ… Common Side Effects

  • Cough
  • Dizziness
  • Hypotension
  • Hyperkalemia
  • Rash
  • Taste disturbance

๐Ÿšจ Serious Side Effects

  • Angioedema
  • Neutropenia/agranulocytosis
  • Renal failure
  • Hepatotoxicity
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Pancreatitis
  • Pulmonary edema
  • Aplastic anemia
  • Hemolytic anemia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Potassium-sparing diuretics Major Increased risk of hyperkalemia
Lithium Major Increased lithium levels and toxicity
NSAIDs Major Reduced antihypertensive effect and increased risk of renal impairment
Antihypertensives Moderate Additive hypotensive effect
Diuretics Moderate Enhanced hypotensive effect; risk of hypovolemia
Antidiabetic agents Moderate Increased hypoglycemic effect
Digoxin Moderate Possible increased digoxin levels
Antacids Minor Reduced captopril absorption
Food Minor Reduced absorption

๐Ÿšจ Major Interactions

  • Potassium-sparing diuretics
  • Potassium supplements
  • Lithium
  • NSAIDs

โšก Moderate Interactions

  • Antihypertensives
  • Diuretics
  • Antidiabetic agents
  • Digoxin

โ„น๏ธ Minor Interactions

  • Antacids
  • Food

๐Ÿฝ๏ธ Food Interactions

Food may reduce absorption; take on an empty stomach.

๐Ÿท Alcohol Interaction

Alcohol may enhance hypotensive effect; avoid excessive use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to captopril or other ACE inhibitors, history of angioedema, bilateral renal artery stenosis, pregnancy.

๐Ÿ“Š Monitoring Parameters

Blood pressure, renal function, serum potassium, white blood cell count, urine protein.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in low amounts; use with caution.

๐Ÿ’Š Overdose Management

Supportive treatment; gastric lavage, activated charcoal, and correction of hypotension with IV fluids and vasopressors.

โฐ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for aceten 12.5mg tablet

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Alternative brands with exact same active ingredient (Captopril (12.5mg)):

Medical Note: Always consult your doctor before switching medications.

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