Acyclosure TH 8 Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is aceprime 8t tablet used for?
This medicine is a combination of Aceclofenac (an NSAID) and Thiocolchicoside (a muscle relaxant) used for short-term relief of acute musculoskeletal pain and muscle spasm. It is taken orally, usually twice daily with food, and should not be used for prolonged periods without medical supervision.
- Generic Name: Aceclofenac + Thiocolchicoside
- Manufacturer: Ventus Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aceprime 8t tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटोक्लोफेनाक और थायोकोल्चिकोसाइड का संयोजन है, जिसका उपयोग तीव्र मस्कुलोस्केलेटल दर्द और मांसपेशियों की ऐंठन के इलाज के लिए किया जाता है। यह दर्द और सूजन को कम करने के साथ-साथ मांसपेशियों को आराम देती है। यह आमतौर पर कमर दर्द, गर्दन दर्द, चोट या सर्जरी के बाद के दर्द में उपयोग की जाती है। इसका उपयोग केवल डॉक्टर की सलाह पर ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, दस्त, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत विषाक्तता और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या पेशाब कम आना जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब का सेवन न करें। यदि आपको चक्कर या नींद आती है तो वाहन न चलाएं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या गुर्दे/यकृत की बीमारी है तो डॉक्टर को बताएं। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें।
💊 aceprime 8t tablet Uses & Benefits
[{"condition":"Acute low back pain with muscle spasm","description":"Relieves pain and reduces muscle spasm, improving mobility.","evidence":"Well-established"},{"condition":"Neck pain (cervical spondylosis) with spasm","description":"Reduces pain and relaxes neck muscles, easing movement.","evidence":"Well-established"},{"condition":"Post-traumatic pain and inflammation" class="semantic-link" title="Medicines for swelling">swelling","description":"Alleviates pain and inflammation after injuries like sprains or strains.","evidence":"Well-established"},{"condition":"Post-operative pain and spasm","description":"Used for short-term management of pain and muscle spasm after surgery.","evidence":"Moderate"},{"condition":"Osteoarthritis flare-up","description":"Provides symptomatic relief of pain and stiffness during acute exacerbations.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Tension-type headache","description":"Sometimes prescribed off-label for tension headaches with muscle spasm.","evidence":"Limited"},{"condition":"Fibromyalgia","description":"May be used off-label for short-term relief of muscle pain, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Acute musculoskeletal pain with muscle spasm
Also treats: Low back pain, Neck pain, Post-traumatic pain, Post-operative pain, Osteoarthritis flare
📋 Drug Information
| Generic Name(s) | Aceclofenac + Thiocolchicoside |
| Brand Name | Aldigesic TH 100mg/4mg Tablet |
| Manufacturer | Ventus Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Muscle Relaxant |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, thereby reducing the production of prostaglandins which are mediators of pain and inflammation. Thiocolchicoside is a centrally acting muscle relaxant that acts as a GABA-A receptor agonist, enhancing inhibitory neurotransmission in the spinal cord and brainstem, which reduces muscle spasm. Together, they provide both anti-inflammatory and muscle relaxant effects.
Mechanism Steps
💡 How to Take aceprime 8t tablet
Strength: Tablet containing Aceclofenac 100 mg and Thiocolchicoside 8 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally twice daily, preferably with food. However, the dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function. Do not exceed the prescribed dose. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use with caution and lower doses may be appropriate. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet twice daily (Aceclofenac 200 mg + Thiocolchicoside 16 mg). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aceprime 8t tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| Antihypertensives | Moderate | |
| SSRIs | Moderate | |
| Oral hypoglycemics | Moderate | |
| Cyclosporine | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (ACE inhibitors, ARBs, diuretics)
- SSRIs
- Oral hypoglycemics
- Cyclosporine
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver toxicity. It may also enhance drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Aceclofenac, Thiocolchicoside, or any component of the formulation","History of asthma, urticaria, or allergic reactions to NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe heart failure, kidney impairment, or liver impairment","Third trimester of pregnancy","Children under 18 years (safety not established)","Patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption"]
⚠️ Warnings & Precautions
["Take with food to minimize gastrointestinal irritation.","Avoid alcohol consumption.","Do not drive or operate machinery if you experience dizziness or drowsiness.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma.","Do not use for longer than prescribed without medical advice.","Monitor for signs of bleeding or bruising.","Avoid concurrent use with other NSAIDs."]
🤱 Lactation Safety
Not established from the available information. Aceclofenac and Thiocolchicoside may pass into breast milk. Consult your doctor before use if breastfeeding.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, abdominal pain, gastrointestinal bleeding, drowsiness, and kidney impairment. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and renal function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Always take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine as it can increase the risk of gastrointestinal bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Do not take other NSAIDs or pain relievers without consulting your doctor. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution and lower doses may be appropriate. Regular monitoring of kidney and liver function is recommended.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are planning pregnancy or are pregnant. Consult your doctor for alternative pain management options.
🏥 Post-Surgery Considerations
This medicine may be prescribed for short-term post-operative pain and muscle spasm. Use only as directed by your surgeon. Inform your surgeon if you have any underlying conditions.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. Your dentist may advise stopping it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you have muscle spasm or pain. Gentle stretching and low-impact activities may be beneficial. Consult your doctor or physiotherapist for guidance.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Generally, it does not significantly interfere with desk work.
🛑 When to Stop This Medicine
Stop taking this medicine if your doctor advises, or if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or kidney problems. Do not stop abruptly without consulting your doctor if you have been on long-term therapy.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function is advised. It should not be used for prolonged periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve muscle strength.
Evidence: Well-establishedApplying heat or cold packs can help relieve muscle spasm and pain.
Evidence: ModerateMay provide pain relief for some individuals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There are no known interactions with vaccines. However, consult your doctor before any vaccination while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature, away from direct sunlight and moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30-60 minutes after taking the tablet.
A: It is best taken with food to reduce stomach irritation.
A: Do not take with other NSAIDs without consulting your doctor, as it increases risk of side effects.
A: It is not recommended during pregnancy, especially in the third trimester. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for aceprime 8t tablet
View AllAlternative brands with exact same active ingredient:
-
edoclof-max tabletEdmund Healthcare ₹32.81 86.7% CHEAPER
-
xynac th 100mg/8mg tabletArlak Biotech Pvt Ltd ₹67.50 72.7% CHEAPER
-
Thiochy A 100mg/8mg TabletMelody Healthcare Private Limited ₹92.81 62.5% CHEAPER
-
Thiodal 100mg/8mg TabletSapiens Labs Pvt Ltd ₹105.00 57.6% CHEAPER
-
thioceclo 100mg/8mg tablet srAristo Pharmaceuticals Pvt Ltd ₹128.30 48.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: It is intended for short-term use only. Long-term use increases risk of side effects. - Myth: It is safe to take on an empty stomach.
Fact: It should be taken with food to reduce stomach irritation. - Myth: It can be combined with other painkillers.
Fact: Combining with other NSAIDs increases risk of bleeding and kidney problems.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac + Thiocolchicoside combination tablets from other manufacturers
Brand Alternatives
- Acyclosure TH 8 Tablet